Asian Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
12(9)
Published: July 27, 2023
Abstract
A
novel
and
unique
activation
method
for
esters
possessing
a
non‐activated
cyclopropyl
moiety
as
potential
activating
group
is
developed
acyl
fluoride
generation
using
hypervalent
iodine(III)
reagent
Selectfluor.
The
resulting
fluoride,
which
versatile
synthetic
intermediate,
was
smoothly
transformed
into
the
various
carbonyl
compounds,
in
particular,
amides.
This
protocol
can
be
applied
to
chemoselective
of
diester
compounds.
Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(5), P. 2794 - 2799
Published: Jan. 25, 2023
A
photoexcited-nitroarene-mediated
anaerobic
C-H
hydroxylation
of
aliphatic
systems
is
reported.
The
success
this
reaction
due
to
the
bifunctional
nature
photoexcited
nitroarene,
which
serves
as
bond
activator
and
oxygen
atom
source.
Compared
previous
methods,
approach
cost-
atom-economical
commercial
availability
sole
mediator
reaction.
Because
conditions
transformation,
a
noteworthy
expansion
in
substrate
scope
can
be
obtained
compared
prior
reports.
Mechanistic
studies
support
that
nitroarenes
engage
successive
hydrogen
transfer
radical
recombination
events
with
hydrocarbons,
leading
N-arylhydroxylamine
ether
intermediates.
Spontaneous
fragmentation
these
intermediates
leads
key
products.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(9), P. 2638 - 2664
Published: Jan. 1, 2024
This
review
describes
the
recent
advances
in
different
reaction
types
and
catalytic
systems
for
construction
of
C–NAr
S–NAr
bonds
by
nitroaromatic
reductive
cross-coupling.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(19), P. 2771 - 2774
Published: Jan. 1, 2023
A
direct
dehydrogenative
amidation
reaction
of
aldehydes
and
amines
under
a
visible
light
mediated
ligand-to-metal
charge
transfer
(LMCT)
process
was
described.
In
this
protocol,
aldehyde
substrates
were
activated
by
photoinduced
hydrogen
atom
abstraction
(HAA),
generating
acyl
chloride
intermediates
followed
nucleophilic
addition
amines.
The
synthetic
method
furnishes
good
functional
group
tolerance
broad
substrate
scope
toward
both
aliphatic
aromatic
components.
Organic Chemistry Frontiers,
Journal Year:
2023,
Volume and Issue:
10(17), P. 4394 - 4399
Published: Jan. 1, 2023
Herein,
we
report
an
effective
C–H
bond
activation-alkylation
strategy
for
2-iodobenzoyl
protected
cyclic
amines
at
the
N
-α-position
through
a
visible-light
mediated
1,5-hydrogen
atom
transfer
(HAT)
process.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(24), P. 4592 - 4597
Published: June 12, 2023
A
fully
catalytic
nickel-photoredox
process
for
the
direct
amidation
of
aldehydes
with
nitroarenes
was
developed.
In
this
system,
and
were
catalytically
activated
by
photocatalytic
cycle
without
addition
an
additional
reductant
or
oxidants,
which
facilitated
Ni-mediated
cross-coupling
C-N
bond
under
mild
conditions.
preliminary
mechanistic
study
indicates
a
reaction
pathway
in
nitrobenzene
is
directly
reduced
to
aniline
as
nitrogen
source.
Green Chemistry,
Journal Year:
2023,
Volume and Issue:
25(14), P. 5735 - 5740
Published: Jan. 1, 2023
An
unprecedented
straightforward
reductive
amidation
of
chloroalkanes
with
nitroarenes
was
readily
accomplished
by
merging
iron
catalysis
visible-light
photoredox
catalysis.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(67), P. 8806 - 8823
Published: Jan. 1, 2024
Distinct
reactivity
and
chemoselectives
of
photoexcited
nitroarenes
under
visible
light
irradiation
such
as
reductive
C–N
coupling,
anaerobic
oxidation,
annulation,
scaffold
diversification
via
nitrene
insertion,
etc.
,
are
highlighted.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(7), P. 2095 - 2101
Published: Jan. 1, 2024
A
mild
and
efficient
visible-light
promoted
FeCl
3
-catalyzed
reductive
transamidation
of
N
-acyl
benzotriazoles
with
nitro
compounds
by
PhSiH
was
developed.
Organic Letters,
Journal Year:
2022,
Volume and Issue:
24(36), P. 6642 - 6646
Published: Sept. 6, 2022
We
report
a
C–N
cross-coupling
reaction
of
weakly
nucleophilic
N-arylsulfonamides
and
aryl
bromides
to
access
N,N-diarylsulfonamides
using
Ni(cod)(DQ)
as
catalyst
without
additional
ligands.
The
process
is
compatible
with
electron-deficient
electron-rich
heteroaryl
(34
examples,
21–98%)
can
be
applied
the
derivatization
an
N-arylsulfonamide
pharmaceutical
compound.
