A review on zirconium-based metal–organic frameworks: synthetic approaches and biomedical applications
Materials Advances,
Journal Year:
2023,
Volume and Issue:
5(1), P. 51 - 67
Published: Nov. 21, 2023
Zr-MOFs,
known
for
stability,
low
cytotoxicity
and
high
drug-loading
capacity;
have
been
thoroughly
investigated
biomedical
uses.
This
article
reviews
the
various
synthetic
methods
recent
applications
of
important
Zr-based
MOFs.
Language: Английский
Advancements in porous framework materials for chemiresistive hydrogen sensing: Exploring MOFs and COFs
Dalton Transactions,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Semiconductor
metal
oxides
detect
H
2
even
at
the
ppm
level
but
need
high
temperatures
and
oxygen.
MOFs/COFs
higher
concentrations,
work
lower
temperatures,
perform
very
well
under
inert
conditions.
Language: Английский
Preparation and Characterization of Muscone Oil-Based Cyclodextrin Metal–Organic Frameworks: Molecular Dynamics Simulations and Stability Evaluation
Pharmaceutics,
Journal Year:
2025,
Volume and Issue:
17(4), P. 497 - 497
Published: April 9, 2025
Objective:
Muscone
(MUS),
a
primary
active
component
of
musk,
is
known
for
its
significant
pharmacological
properties.
However,
clinical
application
limited
due
to
poor
water
solubility
and
moderate
stability.
This
study
aims
address
these
limitations
by
encapsulating
MUS
within
biodegradable
γ-cyclodextrin
metal–organic
frameworks
(γ-CD-MOFs)
using
solvent-free
method
enable
oral
delivery
improving
stability,
pending
in
vivo
validation.
Methods:
was
encapsulated
into
γ-CD-MOFs
method,
achieving
an
optimal
loading
rate
10.6
±
0.7%.
Comprehensive
characterization
performed
scanning
electron
microscopy
(SEM),
X-ray
diffraction
(XRD),
Fourier-transform
infrared
spectroscopy
(FTIR),
thermogravimetric
analysis
(TGA).
Biocompatibility
assessed
RAW264.7
cells,
molecular
dynamics
simulations
were
conducted
the
interactions
between
γ-CD-MOFs.
Results:
Characterization
techniques
confirmed
successful
encapsulation
studies
revealed
no
cytotoxicity,
indicating
that
system
safe
drug
delivery.
Molecular
showed
preferentially
occupies
large
spherical
cages
γ-CD-MOFs,
driven
non-covalent
interactions.
Solubility
tests
vitro
release
demonstrated
improved
after
Stability
assessments
indicated
significantly
enhanced
thermal
photostability
MUS,
with
high
residual
amounts
remaining
under
various
storage
conditions.
Conclusions:
demonstrates
potential
solidify
enhance
solubility,
improve
providing
foundation
future
use
pharmaceutical
applications.
Language: Английский
CoCorrole‐Functionalized PCN‐222 for Carbon Monoxide Selective Adsorption
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 22, 2024
The
high
risk
of
CO
poisoning
justifies
the
need
for
indoor
air
quality
control
and
warning
systems
based
on
detection
low
concentrations
(ppm-ppb)
CO.
Cobalt
corrole
complexes
selectively
bind
vs.
O
Language: Английский
CuI Coordination Polymer‐Catalyzed Azide–Alkyne Cycloaddition Click Reaction at Room Temperature
European Journal of Inorganic Chemistry,
Journal Year:
2023,
Volume and Issue:
27(2)
Published: Nov. 2, 2023
Abstract
Framework
based
compounds
for
eco‐friendly
catalysis
is
of
utmost
industrial
interest.
Cu
I
‐catalyzed
“click”
reactions
are
a
class
highly
efficient
and
widely
used
chemical
in
organic
synthesis
potential
applications
biotechnology,
medicine,
polymer,
material
sciences.
The
importance
click
chemistry
also
acknowledge
by
2022
Noble
Prize
chemistry.
One
the
most
well‐known
copper‐catalyzed
azide‐alkyne
cycloaddition
(CuAAC),
which
type
Huisgen
1,3‐dipolar
reaction.
Herein,
three
stable
copper(I)‐coordination
polymers
(CPs),
[Cu(4‐ABPT)Cl],
CP‐1
;
[Cu(4‐ABPT)Br],
CP‐2
[Cu
2
(4‐ABPT)
0.5
],
CP‐3
(4‐ABPT=3,5‐di(pyridine‐4‐yl)‐4H‐1,2,4‐triazol‐4‐amine)
have
been
chosen
CuAAC
reaction,
due
to
presence
both
Lewis
acidic
(copper
ion),
basic
(pyridyl
amine)
sites.
counter
anion
plays
crucial
role
their
structural
motif
as
well
catalytic
efficiency.
These
easily
synthesizable
scalable
catalysts
exhibit
trend
>
selective
conversion
phenylacetylene,
benzyl
bromide,
sodium
azide
into
1,4‐cycloaddition
product
within
h
at
ambient
temperature
solvent
free
reaction
conditions.
using
catalyst
exhibits
near
quantitative
room
we
demonstrated
bulk‐scale
CPs
under
mild
Language: Английский