Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(1)
Published: Jan. 1, 2025
Language: Английский
Citations
3Recent trends in nanozyme research and their potential therapeutic applications
Current Research in Biotechnology, Journal Year: 2024, Volume and Issue: 7, P. 100205 - 100205
Published: Jan. 1, 2024
Nanozymes are a class of nanoparticles that can mimic enzyme activity and be used for various applications in modern clinical therapy. It has recently been observed nanozymes have multi-enzyme mimicking activities, highly stable, versatile easily modified. Moreover, they high catalytic efficiency, recovery rates, improved substrate specificity suitable mass production. The mechanisms mainly include catalase, peroxidase, oxidase, hydrolase superoxide dismutase-like which enable to as potential therapeutics against plethora infectious lifestyle disorders. cancer, inflammatory diseases, neurodegenerative neurological disorders, bacterial, fungal viral infections, wounds diseases associated with Reactive Oxygen Species. purpose writing this review is provide comprehensive compilation novel research work taken place the last few years regarding use We compiled kinds elaborated on their anti-tumorigenic, antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, neuroprotective roles. Their modes action enzymatic targets also discussed. types synthesis summarized, along interactions nanozymes. Furthermore, strategies enhance compatibility between analyzed. Major focus laid therapeutic challenges future perspectives using therapy debated later sections.
Language: Английский
Citations
18Specific and enzyme-free monitoring of propiconazole pesticide residues in vegetables with a portable nanozyme-based paper sensor
Food Chemistry, Journal Year: 2024, Volume and Issue: 464, P. 141686 - 141686
Published: Oct. 17, 2024
Language: Английский
Citations
6Revolutionizing nanozyme technology with metal-organic frameworks: Classification, catalytic mechanisms, regulation and applications in biotechnology
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 156850 - 156850
Published: Oct. 1, 2024
Language: Английский
Citations
3Advances in Oxygenation Nanozyme for Overcoming Diabetic Ulcer
Biomaterials Science, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Diabetic ulcers, affecting 15-25% of diabetes patients worldwide, are characterized by localized hypoxia that impedes healing. This review explores the emerging field in situ oxygen-generating nanozymes as a promising approach to diabetic ulcer treatment. Nanozymes, synthetic nanoparticles mimicking natural enzyme activities, have shown potential generating oxygen situ, scavenging reactive species, and modulating wound microenvironment. Materials such manganese dioxide, cerium platinum nanoparticles, molybdenum-based quantum dots demonstrated efficacy preclinical studies, often exhibiting multiple enzyme-like activities. These accelerated closure, enhanced angiogenesis, improved tissue regeneration animal models. However, challenges remain, including optimizing nanozyme-hydrogel interactions, addressing toxicity metal-based nanomaterials, determining optimal concentrations for various conditions. Future research directions include developing biocompatible nanozymes, enhancing delivery systems, exploring combination therapies. underscores nanozyme-based therapies revolutionize treatment ulcers potentially other hypoxia-related
Language: Английский
Citations
0A MOF-818-based nanozyme-linked aptasensor for microcystin-LR detection in edible algae powder
Talanta, Journal Year: 2025, Volume and Issue: 295, P. 128257 - 128257
Published: May 2, 2025
Language: Английский
Citations
0Opto-electrochemical transducers for molecular sensing utilizing nanozyme-based sensing technologies
Microchemical Journal, Journal Year: 2024, Volume and Issue: 205, P. 111360 - 111360
Published: Aug. 4, 2024
Language: Английский
Citations
2Nanozymes: Classification and Analytical Applications – A Review
Journal of Fluorescence, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 13, 2024
Language: Английский
Citations
2Colorimetric Immunoassays with Boronic Acid-Decorated, Peroxidase-Like Metal-Organic Frameworks as the Carriers of Antibodies and Enzymes
Molecules, Journal Year: 2024, Volume and Issue: 29(13), P. 3000 - 3000
Published: June 24, 2024
The sensitivity of immunoassays is generally limited by the low signal reporter/recognition element ratio. Nanomaterials serving as carriers can enhance loading number reporters, thus improving detection sensitivity. However, general immobilization strategies, including direct physical adsorption and covalent coupling, may cause random orientation conformational change in proteins, partially or completely suppressing enzymatic activity molecular recognition ability. In this work, we proposed a strategy to load elements antibodies enzyme labels using boronic acid-modified metal-organic frameworks (MOFs) nanocarriers for amplification. conjugation was based on boronate ester interactions between carbohydrate moieties enzymes acid MOFs. Both MOFs could catalyze oxidation 3,3′,5,5′-tetramethylbenzidine (TMB) H2O2, therefore achieving dual To indicate feasibility strategy, colorimetric prostate specific antigen (PSA) were performed with Cu-MOFs peroxidase mimics TMB antibody (horseradish peroxidase, HRP). According absorbance intensity oxidized (oxTMB), PSA at concentration range 1~250 pg/mL be readily determined. addition, work presented site-specific oriented modification nanolabels which should valuable design novel biosensors high selectivity.
Language: Английский
Citations
0Enhanced oxidoreductase activity of diatom frustule supported Fe3O4 for sensitive colorimetric detection of Cr(VI)
Journal of Photochemistry and Photobiology A Chemistry, Journal Year: 2024, Volume and Issue: 457, P. 115895 - 115895
Published: July 20, 2024
Language: Английский
Citations
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