Bioengineering,
Journal Year:
2023,
Volume and Issue:
10(12), P. 1373 - 1373
Published: Nov. 29, 2023
In
the
early
years
of
tissue
engineering,
scientists
focused
on
generation
healthy-like
tissues
and
organs
to
replace
diseased
areas
with
aim
filling
gap
between
organ
demands
actual
donations.
Over
time,
realization
has
set
in
that
there
is
an
additional
large
unmet
need
for
suitable
disease
models
study
their
progression
test
refine
different
treatment
approaches.
Increasingly,
researchers
have
turned
engineering
address
this
controllable
translational
models.
We
review
existing
potential
uses
tissue-engineered
cardiovascular
research
suggest
guidelines
generating
adequate
models,
aimed
both
at
studying
mechanisms
supporting
development
dedicated
drug-delivery
therapies.
This
involves
discussion
requirements
drugs,
nanoparticles,
drug-eluting
devices.
addition
realistic
cellular
composition,
mechanical
structural
properties
are
needed
simulate
pathological
reality
addressed.
Advanced Healthcare Materials,
Journal Year:
2024,
Volume and Issue:
14(4)
Published: Dec. 29, 2024
4D
bioprinting
is
a
critical
advancement
in
tissue
engineering
and
regenerative
medicine
(TERM),
enabling
the
creation
of
structures
that
dynamically
respond
to
environmental
stimuli
over
time.
This
review
investigates
various
fabrication
techniques
responsive
materials
are
central
these
fields.
It
underscores
integration
multi-material
biocomposite
approaches
bioprinting,
which
crucial
for
fabricating
complex
functional
constructs
with
heterogeneous
properties.
Using
enhances
mimicry
natural
characteristics,
offering
tailored
responses
improved
biological
systems.
Furthermore,
this
study
highlights
synergy
between
demonstrates
technology's
potential
developing
tissues
organs.
In
medicine,
bioprinting's
applications
extend
creating
smart
implants
advanced
drug
delivery
systems
adapt
body's
changes,
promoting
healing
regeneration.
Finally,
challenges
future
directions
also
explored
emphasize
its
transformative
impact
on
biomedical
healthcare.
Bioengineering,
Journal Year:
2023,
Volume and Issue:
10(12), P. 1373 - 1373
Published: Nov. 29, 2023
In
the
early
years
of
tissue
engineering,
scientists
focused
on
generation
healthy-like
tissues
and
organs
to
replace
diseased
areas
with
aim
filling
gap
between
organ
demands
actual
donations.
Over
time,
realization
has
set
in
that
there
is
an
additional
large
unmet
need
for
suitable
disease
models
study
their
progression
test
refine
different
treatment
approaches.
Increasingly,
researchers
have
turned
engineering
address
this
controllable
translational
models.
We
review
existing
potential
uses
tissue-engineered
cardiovascular
research
suggest
guidelines
generating
adequate
models,
aimed
both
at
studying
mechanisms
supporting
development
dedicated
drug-delivery
therapies.
This
involves
discussion
requirements
drugs,
nanoparticles,
drug-eluting
devices.
addition
realistic
cellular
composition,
mechanical
structural
properties
are
needed
simulate
pathological
reality
addressed.
