Iridium-catalyzed reduction of o-hydroxyl phenyl enaminones for the synthesis propiophenones and their application in 3-methyl chromone synthesis DOI

Zhi Tu,

Jie‐Ping Wan, Wei Li

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A method of reducing

Language: Английский

Water-Controlled Geminal Hydroxyphosphinoylation and Diphosphinoylation of Enaminones with H-Phosphine Oxides DOI

Qiang Huang,

Xin Jin, Huabin Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

A water-controlled geminal phosphinoylation of enaminones with H-phosphine oxides has been established through AlCl3-mediated C-N bond cleavage in this work, which provides a novel strategy for accessing various hydroxy and diphosphinoyl products 3a 4a high yields. The transformation features excellent functional group tolerance, operational simplicity, atom economy, is amenable complex molecule skeletons. Preliminary mechanism studies suggest the conversion from to involve elimination hydroxyl group, water temperature plays critical role influencing reaction pathway product selectivity. This research significant value functionalization enaminones.

Language: Английский

Citations

0
PIFA-mediated room temperature dehydrogenative annulation for the synthesis of 2-alkenyl oxazoles DOI
Kang Chen, Jie‐Ping Wan,

Liyun Zhou

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1308, P. 138142 - 138142

Published: March 24, 2024

Language: Английский

Citations

3
Copper(II)‐Catalyzed [2+2+2] Annulation of Enaminones with Maleimides Using a Traceless Directing Group Strategy DOI
Leiqing Fu, Hongxiang Huang, Yingying Jiang

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(19), P. 4139 - 4144

Published: July 2, 2024

Abstract A copper‐catalyzed annulation of enaminones with maleimides was developed to synthesize various pyrrolo[3,4‐e]isoindoles. In this strategy, 2‐aminopyridine served as a traceless directing group, and target products were obtained in 54–72% yields. Moreover, plausible mechanism for reaction proposed based on several control experiments, deuterium exchange previous reports.

Language: Английский

Citations

3
Direct synthesis of Enone-Hydrazones under solvent free and additives free conditions DOI
Kun He,

Weikun Zeng,

Xianglin Yu

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A series of enone-hydrazones were synthesized through the reaction enaminones with hydrazones under solvent-free, additive-free, and metal-catalyst-free conditions.

Language: Английский

Citations

1
Copper(II)-Catalyzed [2+2+2] Annulation of Enaminones with Maleimides by a Traceless Directing Group Strategy DOI Open Access
Leiqing Fu, Hongxiang Huang, Yingying Jiang

et al.

Authorea (Authorea), Journal Year: 2024, Volume and Issue: unknown

Published: June 8, 2024

An efficient copper-catalyzed annulation of enaminones with maleimides has been developed. This reaction provides a practical approach towards the synthesis various pyrrolo[3,4-e]isoindoles in moderate to good yields. Notable features method include use 2-aminopyridine group as traceless directing group, wide scope substrates functional compatibility and applicability gram scale.

Language: Английский

Citations

0
Iridium-catalyzed reduction of o-hydroxyl phenyl enaminones for the synthesis propiophenones and their application in 3-methyl chromone synthesis DOI

Zhi Tu,

Jie‐Ping Wan, Wei Li

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A method of reducing

Language: Английский

Citations

0