Bisindolylmethane
(BIM)
and
its
derivatives
are
widely
used
in
the
pharmaceutical
industry
due
to
their
significant
biological
activities.
However,
most
reported
synthetic
methods
focused
on
synthesis
of
symmetric
BIMs,
while
unsymmetrical
BIMs
remains
a
challenge.
Herein,
an
unprecedented
two-step
one-pot
method
afford
unsymmetrically
substituted
3,3'-BIM
frameworks,
using
methylene
chloride
(DCM)
as
C1-synthon
is
reported.
In
this
protocol,
formation
two
C-C
bonds
can
be
achieved
Catalysis Science & Technology,
Journal Year:
2024,
Volume and Issue:
14(7), P. 1958 - 1966
Published: Jan. 1, 2024
Herein,
atomically
dispersed
Ru
sites
are
encapsulated
within
UiO-66–NH
2
frameworks
to
serve
as
a
highly
active,
selective,
and
stable
catalyst
for
amine
synthesis
via
N
-alkylation
reactions
of
o
-phenylenediamine
with
monohydric
alcohols.
ACS Catalysis,
Journal Year:
2025,
Volume and Issue:
15(3), P. 1973 - 2001
Published: Jan. 20, 2025
Chiral
quaternary
ammonium
ion-pair
organocatalysis
has
been
widely
used
in
the
facile
synthesis
of
chiral
molecules
with
challenging
stereocenters.
Especially,
numerous
asymmetric
nucleophilic
addition
reactions
have
facilitated
this
strategy.
This
review
systematically
summarizes
additions
promoted
by
salts
past
decade.
The
content
is
organized
according
to
types
electrophiles
involved
these
catalytic
transformations.
Our
own
perspectives
on
future
development
within
highly
active
research
field
are
also
provided.
Catalysts,
Journal Year:
2025,
Volume and Issue:
15(3), P. 238 - 238
Published: March 1, 2025
After
attending
both
the
“Decade
to
Educate
in
Sustainable
Development
and
Agenda
30
of
UNESCO”
“ACS
GCI
Pharmaceutical
Roundtable”,
which
focused
on
sustainable
chemistry,
this
article,
a
green
chemistry
contribution
Kamal
Qureshi
protocol
is
offered;
thus,
DIM®
several
its
analogs
(3,3′-diindolylmethanes)
were
suitably
produced
under
protocol.
In
first
stage,
substrate
indol-3-yl
carbinol
was
evaluated
using
mechanochemistry
(the
best
mode)
comparison
other
activating
methods
(near-infrared
microwave
electromagnetic
irradiation
ultrasound),
wishing
highlight
employment
TAFF®,
an
excellent
well-characterized
natural
catalyst
(bentonitic
clay),
acetone,
solvent,
addition
analysis
procedures
real-time.
second
mechanochemical
methodology
extended
produce
set
fifteen
DIMs,
last
use
metric
exhibited
greenness
approach,
with
it
being
important
that,
our
knowledge,
after
search
literature,
time
that
process
has
been
demonstrate
greenness.
ACS Applied Nano Materials,
Journal Year:
2024,
Volume and Issue:
7(8), P. 8914 - 8925
Published: April 10, 2024
The
nickel
phosphides
have
garnered
increasing
attention
as
an
excellent
catalytic
site
in
the
fields
of
electrocatalysis
and
hydrotreating,
but
their
application
organic
synthesis
remains
infrequent.
In
this
study,
ammonium
phosphate
chloride
were
employed
doping
sources
for
first
time
to
synthesize
Ni-based
ZIF-8
precursor
via
host–guest
method.
Subsequently,
was
pyrolyzed
obtain
Ni2P
nanoparticles
(NPs)
supported
on
N,
P
co-doped
carbon.
composite
materials
exhibit
elevated
metal
loading
effective
dispersion
due
synergistic
combination
phosphorus
nickel.
Specifically,
compared
with
Ni-NC,
optimal
Ni2P-NCP-1
exhibits
enhanced
activity
α-alkylation
arylacetonitriles
alcohols
using
KOH
base.
It
shows
a
wide
broad
substrate
scope
at
140
°C
12
h
n-octane
hydrogen
borrowing
strategy.
Through
characterizations
mechanistic
studies,
it
has
been
discovered
that
introduction
source
not
only
provides
more
basic
sites
carbon
matrix
also
leads
formation
NPs,
which
facilitates
efficiency
by
modifying
electronic
structure
Ni.
Compared
metallic
Ni
species,
effect
between
acid-basic
significantly
influences
dehydrogenation
generate
Ni–H
species.
This
study
successfully
achieves
simultaneous
phosphating
both
support,
demonstrates
N2P-NCP-1
catalyst
significant
potential
heterogeneous
transformation
field.
