Advances in organometallic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 227 - 286
Published: Jan. 1, 2024
Language: Английский
Advances in organometallic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 227 - 286
Published: Jan. 1, 2024
Language: Английский
Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(11), P. 3234 - 3241
Published: Jan. 1, 2024
Herein, we present a cascade O–H double insertion reaction between I (III) /S (VI) -ylides, carboxylic acids, and alcohols under metal-free conditions, enabling the modular synthesis of unsymmetrical α,α- O , -substituted ketones.
Language: Английский
Citations
8New Journal of Chemistry, Journal Year: 2024, Volume and Issue: 48(36), P. 15989 - 15999
Published: Jan. 1, 2024
The [4+1] annulation of sulfoxonium ylides with allyl ether, catalyzed by Rh( iii ), efficiently produces alkyl-substituted indanone a broad substrate scope and excellent yield.
Language: Английский
Citations
4Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
The rare [1,2]-sigmatropic rearrangement of sulfoxonium-iodonium hybrid ylides is described, which enables the efficient sulfoxidation/sulfonylation-alkylation I(III)/S(VI) with 1,3-dicarbonyls. By slight modification reaction conditions, controllable alkylation-hydroxylation and dialkylation were achieved. This strategy affords a diverse array α,α-difunctionalized ketones in moderate to good yields, demonstrating broad substrate scope. These findings provide an important advancement sulfoxonium highlight divergent reactivity ylides.
Language: Английский
Citations
0Organic Letters, Journal Year: 2024, Volume and Issue: 26(29), P. 6263 - 6268
Published: July 12, 2024
A metal-free cascade of α-acyloxylation/carboxamidation I(III)/S(VI)-ylides, carboxylic acids, and isonitriles via a Passerini-like multicomponent reaction is reported. Unexpectedly, [3 + 1+1] cyclization involving I(III)/S(VI)-ylides two molecules ethyl isocyanoacetate was observed. The strategy allows for the synthesis unsymmetrical α,α-disubstituted ketones functionalized pyrroles with up to 99% yield wide substrate compatibility. Notably, procedure has been extended late-stage modification drugs natural products, offering an elegant complement classic Passerini reaction.
Language: Английский
Citations
2Advances in organometallic chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 227 - 286
Published: Jan. 1, 2024
Language: Английский
Citations
0