Electrophotoredox cerium-catalyzed decarboxylative radical cyclization cascade for the synthesis of alkylated benzimidazo-fused isoquinolinones DOI
Meng Wang,

Dehui Wang,

Kun Xu

et al.

Catalysis Science & Technology, Journal Year: 2024, Volume and Issue: 14(4), P. 1037 - 1042

Published: Jan. 1, 2024

We report an electrophotoredox cerium-catalyzed LMCT strategy to incorporate carboxylic acids into radical cyclization cascades. This protocol provides a solution address the challenges in alkylated benzimidazo-fused isoquinolinone synthesis.

Language: Английский

Paired Electrolysis-Enabled Arylation of Quinoxalin-2(1H)-ones DOI

Jia-Cheng Hou,

Jun Jiang,

Yan-Cui Wen

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(9), P. 6117 - 6125

Published: April 24, 2024

The first paired electrolysis-enabled arylation of quinoxalin-2(1H)-ones was achieved using cyanoarenes as the reagents. A variety 3-arylquinoxalin-2(1H)-ones with various important functional groups were obtained in moderate to good yields under metal- and chemical oxidant-free conditions. With a pair reductive oxidative processes occurring among substrates reaction intermediates, power consumption can be dramatically reduced.

Language: Английский

Citations

22
Paired Electrolysis Enabled Trifluoromethylheteroaromatization of Alkenes and Alkyne with Trifluoromethyl Thianthrenium Triflate (TT-CF3+OTf–) as a Bifunctional Reagent DOI
Xiang Fang,

Dehui Wang,

Kun Xu

et al.

Organic Letters, Journal Year: 2023, Volume and Issue: 26(1), P. 411 - 415

Published: Dec. 26, 2023

We report a strategic exploitation of trifluoromethyl thianthrenium triflate (TT-CF3+OTf–) as both electromediator and CF3 radical precursors for paired electrolysis. Enabled by this strategy, the three-component trifluoromethylheteroaromatization alkenes alkynes was realized. The superiority TT-CF3+OTf– to other electrophilic reagents is attributed cathodic generation thianthrene (TT) mediator, which shifts heterogeneous oxidation interest homogeneous one.

Language: Английский

Citations

26
Electroreductively driven C–H functionalization of arenes DOI
Pengfei Xie,

Anzai Shi,

Youai Qiu

et al.

Chem Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 101359 - 101359

Published: April 1, 2025

Language: Английский

Citations

0
Electrophotoredox cerium-catalyzed decarboxylative radical cyclization cascade for the synthesis of alkylated benzimidazo-fused isoquinolinones DOI
Meng Wang,

Dehui Wang,

Kun Xu

et al.

Catalysis Science & Technology, Journal Year: 2024, Volume and Issue: 14(4), P. 1037 - 1042

Published: Jan. 1, 2024

We report an electrophotoredox cerium-catalyzed LMCT strategy to incorporate carboxylic acids into radical cyclization cascades. This protocol provides a solution address the challenges in alkylated benzimidazo-fused isoquinolinone synthesis.

Language: Английский

Citations

3