Stable CAAC‐triazenes: A New Nitrogen Ligand System with Donor and Conformational Flexibility, and with Application in Olefin Activation Catalysis
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(38)
Published: April 30, 2024
N-heterocyclic
imines
such
as
pyridylidene
amines
impart
high
catalytic
activity
when
coordinated
to
a
transition
metal,
largely
imposed
by
their
electronic
flexibility.
Here,
this
donor
flexibility
has
been
applied
for
the
first
time
CAAC-based
systems
through
synthesis
of
CAAC-triazenes.
These
new
ligands
offer
larger
π-conjugation
that
extends
from
carbene
three
nitrogens
rather
than
just
one,
observed
in
imines.
We
demonstrate
straightforward
CAAC-triazenes
containing
different
substituents
on
terminal
triazene
nitrogen.
compounds
are
remarkably
stable
up
120
°C
without
loss
N
Language: Английский
Functionalization of Siloxanes with Arynes Generated from <i>o</i>-Triazenylarylboronic Acids
Motoki Ito,
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Ryuhei Oda,
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Akari Shoji
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et al.
Chemical and Pharmaceutical Bulletin,
Journal Year:
2024,
Volume and Issue:
72(5), P. 487 - 497
Published: May 20, 2024
Herein,
we
report
the
functionalization
of
polyhedral
oligosilsesquioxanes
(POSS)
and
related
siloxanes
with
arynes.
Using
o-triazenylarylboronic
acids
as
aryne
precursors
silica
gel
activator,
transformation
siloxane
bearing
various
arynophilic
moieties
on
side
chains
was
achieved
high
yields
without
touching
core.
This
method
applied
to
conjugation
POSS
pharmaceutical
cores
using
an
derived
from
synthetic
intermediate
cabozantinib.
Furthermore,
orthogonal
dual
realized
by
combining
reaction
Huisgen
cyclization.
Language: Английский