Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 9, 2024
Abstract
Starting
from
N
‐acyl
sulfonimidamides,
mechanochemically
generated
rhodium
nitrenoids
undergo
intramolecular
N−O
couplings
to
provide
unprecedented
1,3,2,4‐oxathiadiazole
3‐oxides
in
good
excellent
yields.
The
cyclization
proceeds
efficiently
with
a
catalyst
loading
of
only
0.5
mol
%
the
presence
phenyliodine(III)
diacetate
(PIDA)
as
oxidant.
Neither
an
inert
atmosphere
nor
additional
heating
is
required
this
solvent‐free
procedure.
Under
heat
or
blue
light,
newly
formed
five‐membered
heterocycles
function
nitrene
precursors
reacting
sulfoxides
exemplified
by
imidation
dimethyl
sulfoxide.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(14)
Published: Jan. 5, 2024
Abstract
Mechanochemical
reactions
offer
methodological
and
environmental
advantages
for
chemical
synthesis,
constantly
attracting
attention
within
the
scientific
community.
Besides
unmistakable
sustainability
advantages,
conditions
under
which
mechanochemical
occur,
namely
solventless
conditions,
sometimes
facilitate
isolation
of
otherwise
labile
or
inaccessible
products.
Despite
these
limited
knowledge
exists
regarding
mechanisms
types
intermediates
involved.
Nevertheless,
in
an
expanding
number
cases,
ex
situ
monitoring
techniques
have
allowed
observation,
characterization,
reaction
transformations.
In
this
Minireview,
we
present
a
series
examples
reactive
been
detected
spanning
organic,
organometallic,
inorganic,
materials
chemistry.
Many
were
stabilized
by
non‐covalent
interactions,
played
pivotal
role
guiding
We
believe
that
uncovering
understanding
such
instances,
growing
mechanochemistry
community
could
find
novel
opportunities
catalysis
discover
new
while
achieving
simplification
design.
ChemSusChem,
Journal Year:
2024,
Volume and Issue:
17(8)
Published: Jan. 10, 2024
Abstract
As
of
December
2023,
the
use
common
solvent
N
,
‐dimethyl
formamide
(DMF)
will
be
restricted
in
European
Union
because
its
reproductive
health
hazard.
Industrial
facilities
must
comply
with
stricter
exposure
limits,
and
researchers
are
recommended
to
find
alternative
solvents.
Here
we
explain
restrictions
on
DMF,
which
disciplines
affected,
how
substitute
DMF
keep
research
development
commercially
relevant.
RSC Mechanochemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Subtle
differences
in
how
pyridine
is
introduced
can
direct
mechanochemical
reactivity
by
enabling
bond
activation
and
favoring
one
reaction
pathway
over
another.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(14)
Published: Jan. 5, 2024
Abstract
Mechanochemical
reactions
offer
methodological
and
environmental
advantages
for
chemical
synthesis,
constantly
attracting
attention
within
the
scientific
community.
Besides
unmistakable
sustainability
advantages,
conditions
under
which
mechanochemical
occur,
namely
solventless
conditions,
sometimes
facilitate
isolation
of
otherwise
labile
or
inaccessible
products.
Despite
these
limited
knowledge
exists
regarding
mechanisms
types
intermediates
involved.
Nevertheless,
in
an
expanding
number
cases,
ex
situ
monitoring
techniques
have
allowed
observation,
characterization,
reaction
transformations.
In
this
Minireview,
we
present
a
series
examples
reactive
been
detected
spanning
organic,
organometallic,
inorganic,
materials
chemistry.
Many
were
stabilized
by
non‐covalent
interactions,
played
pivotal
role
guiding
We
believe
that
uncovering
understanding
such
instances,
growing
mechanochemistry
community
could
find
novel
opportunities
catalysis
discover
new
while
achieving
simplification
design.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: May 27, 2024
Nitroxides
find
application
in
various
areas
of
chemistry,
and
a
more
in-depth
understanding
factors
controlling
their
reactivity
with
metal
complexes
is
warranted
to
promote
further
developments.
Here,
we
report
on
the
effect
centre
Lewis
acidity
both
distribution
O-
N-centered
spin
density
2,2,6,6-tetramethylpiperidine-N-oxyl
(TEMPO)
turning
TEMPO
from
N-radical
mode
scavenger
metal-TEMPO
systems.
We
use
Et(Cl)Zn/TEMPO
model
reaction
system
tuneable
solid
state
solution.
Among
products,
unique
acid-base
adduct
Cl
ACS Catalysis,
Journal Year:
2024,
Volume and Issue:
unknown, P. 13747 - 13758
Published: Aug. 30, 2024
With
the
growing
emphasis
on
cost-
and
atom-economical
chemical
synthesis,
mechanochemistry
has
attracted
considerable
attention
for
providing
environmentally
friendly
alternatives
to
traditional
solvent-based
organic
transformations.
Herein,
we
demonstrate
use
of
facilitate
alkene
dihalogenation
via
iron-mediated
radical
ligand
transfer
(RLT)
catalysis,
producing
diverse
vicinal
dichloro,
dibromo,
bromochloro
molecules.
The
method
is
characterized
by
its
simplicity,
rapid
reaction
time,
high
chemo-
regioselectivity,
broad
functional
group
tolerance,
accommodating
both
activated
unactivated
alkenes
alkynes.
Mechanistic
insights
suggest
nature
these
processes,
underscoring
effectiveness
mechanochemically
driven
RLT
catalysis
modular
functionalization
unsaturated
hydrocarbons.
