Nanoscale Advances,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 1, 2024
Creating
micromotors
(MMs)
that
will
have
the
highest
possible
velocities
has
become
one
of
main
focuses
in
field
autonomous
microdevices
research.
The
importance
velocity
stems
from
various
applications,
ranging
faster
drug
delivery
to
eradication
bacterial
biofilms
using
only
mechanical
movement.
To
investigate
how
different
shapes
affect
Zn/SU-8
acid
solution,
we
fabricated
with
geometries
(Zn/SU-8/Cylindrical,
Zn/SU-8/Rectangular
cuboid,
Zn/SU-8/Triangular
prism,
Zn/SU-8/Pentagonal
prism
and
Zn/SU-8/Pentagrammic
MMs).
This
is
first
comparative
study
where
shape
been
isolated
as
critical
factor
influencing
micromotor
under
same
catalytic
surface
conditions.
Our
results
demonstrate
cuboid
MMs
exhibit
significantly
higher
average
compared
other
studied
MMs.
shape-optimized
micromotors,
characterized
by
their
simple
synthesis
process
low
cost,
offer
significant
potential
enhance
efficiency
navigation
both
environmental
medical
applications
through
precise
movement
control.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(18), P. 9190 - 9253
Published: Jan. 1, 2024
Autonomous
micro/nanorobots
capable
of
performing
programmed
missions
are
at
the
forefront
next-generation
micromachinery.
These
small
robotic
systems
predominantly
constructed
using
functional
components
sourced
from
micro-
and
nanoscale
materials;
therefore,
combining
them
with
various
advanced
materials
represents
a
pivotal
direction
toward
achieving
higher
level
intelligence
multifunctionality.
This
review
provides
comprehensive
overview
for
innovative
micro/nanorobotics,
focusing
on
five
families
that
have
witnessed
most
rapid
advancements
over
last
decade:
two-dimensional
materials,
metal-organic
frameworks,
semiconductors,
polymers,
biological
cells.
Their
unique
physicochemical,
mechanical,
optical,
properties
been
integrated
into
to
achieve
greater
maneuverability,
programmability,
intelligence,
multifunctionality
in
collective
behaviors.
The
design
fabrication
methods
hybrid
discussed
based
material
categories.
In
addition,
their
promising
potential
powering
motion
and/or
(multi-)functionality
is
described
fundamental
principles
underlying
explained.
Finally,
extensive
use
variety
applications,
including
environmental
remediation,
(bio)sensing,
therapeutics,
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 13, 2025
Abstract
Multidrug‐resistant
(MDR)
bacteria
and
their
associated
biofilms
are
major
causative
factors
in
eye
infections,
often
resulting
blindness
presenting
considerable
global
health
challenges.
Presently,
mechano–bactericidal
systems,
which
combine
distinct
topological
geometries
with
mechanical
forces
to
physically
induce
bacterial
apoptosis,
show
promising
potential.
However,
the
physical
interaction
process
between
current
systems
is
generally
based
on
passive
diffusion
or
Brownian
motion
lacks
force
required
for
biofilm
penetration;
thus,
featuring
low
antibacterial
efficacy.
Here,
a
biomimetic
nanomotor
(VMSNT)
synthesized
by
functionalizing
COOH‐PEG‐phenylboronic
acid
(PBA)
virus‐like
mesoporous
silica,
subsequent
partial
coating
of
Au
caps.
Enhanced
self‐thermophoresis
capabilities
shapes,
VMSNT
significantly
improves
effects
penetration.
In
addition,
scanning
electron
microscope
(SEM)
confocal
laser
(CLSM)
analyses
demonstrate
that
can
precisely
target
within
infection
microenvironment,
facilitated
PBA's
ability
recognize
bind
peptidoglycan
surfaces.
Remarkably,
also
effective
eliminating
MDR
reducing
inflammation
mice
models
methicillin‐resistant
Staphylococcus
aureus
(MRSA)
‐infected
keratitis
endophthalmitis,
minimal
adverse
effects.
Overall,
such
presents
approach
addressing
challenges
ocular
infections.
The European Physical Journal E,
Journal Year:
2025,
Volume and Issue:
48(2)
Published: Feb. 1, 2025
In
the
past
years,
amount
of
research
on
active
matter
has
grown
extremely
rapidly,
a
fact
that
is
reflected
in
particular
by
existence
more
than
1000
reviews
this
topic.
Moreover,
field
become
very
diverse,
ranging
from
theoretical
studies
statistical
mechanics
particles
to
applied
work
medical
applications
microrobots
and
biological
systems
artificial
swimmers.
This
makes
it
difficult
get
an
overview
over
as
whole.
Here,
we
provide
such
form
metareview
article
surveys
existing
review
articles
books
matter.
Thereby,
provides
useful
starting
point
for
finding
literature
about
specific
Small,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 12, 2024
Abstract
Tailoring
the
microstructure
of
magnetic
microparticles
is
vital
importance
for
their
applications.
Spiky
particles,
such
as
those
made
from
sunflower
pollens,
have
shown
promise
in
single
cell
treatment
and
biofilm
removal.
Synthetic
methods
that
can
replicate
or
extend
functionality
spiky
particles
would
be
advantageous
widespread
utilization.
In
this
work,
a
wet‐chemical
method
introduced
are
templated
microrod‐stabilized
Pickering
emulsions.
The
morphology
generated
by
upright
attachment
silica
microrods
at
oil‐water
interface
oil
droplets.
with
control
over
length
spikes
obtained
dispersing
hydrophobic
nanoparticles
phase
photopolymerizing
monomer.
dramatically
enhances
colloidal
stability
these
high
ionic
strength
solutions
physiologic
media
human
saliva
saline‐based
suspension.
To
demonstrate
utility,
applied
magnetically
controlled
removal
oral
biofilms
retrieval
bacteria
diagnostic
sampling.
This
expands
toolbox
engineering
microparticle
could
promote
fabrication
functional
microrobots.
Candida
albicans
is
an
opportunistic
fungal
pathogen
of
humans.
It
causes
a
variety
infections
ranging
from
superficial
mucocutaneous
conditions
to
severe
systemic
diseases
that
result
in
substantial
morbidity
and
mortality.
This
frequently
forms
biofilms
resistant
antifungal
drugs
the
host
immune
system,
leading
treatment
failures.
Recent
research
has
demonstrated
potential
nanorobots
penetrate
biological
barriers
disrupt
biofilms.
In
this
perspective
paper,
we
provide
brief
overview
recent
breakthroughs
for
candidiasis
discuss
current
challenges
prospects.
Pharmaceutics,
Journal Year:
2024,
Volume and Issue:
16(9), P. 1188 - 1188
Published: Sept. 8, 2024
Skin
and
soft-tissue
infections
require
significant
consideration
because
of
their
prolonged
treatment
duration
propensity
to
rapidly
progress,
resulting
in
severe
complications.
The
primary
challenge
stems
from
the
involvement
drug-resistant
microorganisms
that
can
form
impermeable
biofilms,
as
well
possibility
infection
extending
deep
into
tissues,
thereby
complicating
drug
delivery.
Dissolving
microneedle
patches
are
an
innovative
transdermal
drug-delivery
system
effectively
enhances
penetration
through
stratum
corneum
barrier,
increasing
concentration
at
site
infection.
They
offer
highly
efficient,
safe,
patient-friendly
alternatives
conventional
topical
formulations.
This
comprehensive
review
focuses
on
recent
advances
emerging
trends
dissolving-microneedle
technology
for
antimicrobial
skin-infection
therapy.
Conventional
antibiotic
microneedles
compared
with
those
based
agents,
such
quorum-sensing
inhibitors,
peptides,
antimicrobial-matrix
materials.
also
highlights
potential
incorporating
chemodynamic,
nanoenzyme
antimicrobial,
photodynamic,
photothermal
antibacterial
therapies.
explores
advantages
various
therapies
emphasizes
combined
application
improve
efficacy
microneedles.
Finally,
this
analyzes
druggability
different
discusses
possible
future
developments.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 18, 2024
Abstract
Electrodynamic
therapy
(EDT)
is
a
promising
alternative
approach
for
antibacterial
therapy,
as
reactive
oxygen
species
(ROS)
are
produced
efficiently
in
response
to
an
electric
field
without
relying
on
endogenous
H
2
O
and
.
However,
the
inherent
toxicity
of
metallic
catalysts
numerous
bacterial
toxins
during
therapeutic
process
still
hinder
its
development.
Herein,
biomimetic
metal–organic
(MOF@EV)
nanosponges
composed
ginger‐derived
extracellular
vesicles
(EVs),
electrodynamic
frameworks
(MOFs)
developed
eradication
infections
absorption
toxins.
The
prolonged
circulation
time
MOF@EV
vivo
facilitates
their
accumulation
at
infection
sites.
More
interestingly,
can
behave
effectively
prevent
host
cells
from
binding
toxins,
thereby
reducing
damage
cells.
Subsequently,
discovered
work
electro‐sensitizers,
which
confirmed
through
both
theoretical
calculation
experimental
verification.
As
result,
ROS
continuously
under
achieve
effective
EDT‐mediated
eradication.
Meanwhile,
treatment
visualized
mice
infected
with
luciferase‐expressing
Staphylococcus
aureus
(
S.
),
excellent
biofilm
capacity
detoxification
efficiency
demonstrated
subcutaneous
abscess
model.
This
provides
strategy
infections.
Nano-/microrobots
have
been
demonstrated
as
an
efficient
solution
for
environmental
remediation.
Their
strength
lies
in
their
propulsion
abilities
that
allow
active
“on-the-fly”
operation,
such
pollutant
detection,
capture,
transport,
degradation,
and
disruption.
Another
advantage
is
versatility,
which
allows
the
engineering
of
highly
functional
solutions
a
specific
application.
However,
latter
can
bring
complexity
to
applications;
versatility
dimensionality,
morphology,
materials,
surface
decorations,
other
modifications
has
crucial
effect
on
resulting
abilities,
compatibility
with
environment,
overall
functionality.
Synergy
between
decorations
its
projection
functionality
object
nanoarchitectonics.
Here,
we
scrutinize
nano-/microrobots
eyes
nanoarchitectonics:
list
general
concepts
help
assess
synergy
limitations
individual
procedures
fabrication
processes
operation
at
macroscale.
The
nanoarchitectonics
approached
from
microscopic
level,
focusing
dimensionality
through
nanoscopic
evaluating
influence
decoration
nanoparticles
quantum
dots,
moving
molecular
single-atomic
level
very
fine
tuning
presented
review
aims
lay
provide
overview
advanced
nano-/microrobot
remediation
beyond.
Advanced Engineering Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 21, 2025
To
overcome
the
propulsion
difficulties
in
low
Reynolds
number
environment,
natural
species
have
developed
their
exclusive
swimming
strategies
after
1000
years
of
evolution.
Inspired
by
those
fascinating
creatures,
diverse
artificial
microrobots
are
proposed
to
achieve
distinctive
biomimetic
motions.
However,
lack
cognition
for
mechanism
hinders
exploration
multimode
biomimicking
microrobots,
especially
at
high‐speed
locomotion.
Herein,
behaviors
micro
sonobot
featured
with
multiple‐layer
tubular
constructions
and
trapped
microbubbles
serving
as
powerful
microengines
reported.
The
observed
speed
achieves
tens
millimeters
per
second.
Different
from
previously
reported
bubble‐loaded
it
is
that
primary
Bjerknes
forces
originating
nonhomogeneous
acoustic
field
make
a
great
contribution
orientation.
Along
streaming
secondary
forces,
including
individual
locomotion
group
aggregation
emerged
theoretically
analyzed.
motion
sonobots
offers
marvelous
potentials
building
multifunctional
micro/nanosystems
nanosurgery,
lab‐on‐a‐chip
biosystems,
chemical
biological
engineering,
environmental
detoxification,
etc.
