Self-assembled nanoprobes for cancer phototheranostics DOI
Sondavid Nandanwar,

Van Kieu Thuy Nguyen,

Dai Lam Tran

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216643 - 216643

Published: April 18, 2025

Language: Английский

Photodynamic Therapy (PDT) in Drug Delivery: Nano-innovations enhancing treatment outcomes DOI Creative Commons

Ahmed N. Al-Jamal,

Ali Fawzi Al-Hussainy,

Bahira Abdulrazzaq Mohammed

et al.

Health Sciences Review, Journal Year: 2025, Volume and Issue: unknown, P. 100218 - 100218

Published: Jan. 1, 2025

Language: Английский

Citations

1
Polypeptide Nanoparticles Obstruct Glucose Supply for NIR-II Fluorescence-Guided Tumor Starvation and Enhanced Mild Photothermal Therapy DOI
Yating Wang, Yixuan Xu,

Dejia Chen

et al.

Published: Jan. 1, 2025

Photothermal therapy (PTT) utilizes localized hyperthermia above 50°C generated by nanomaterials upon exposure to near-infrared (NIR) laser light for effective cancer cell eradication. Yet, in high-temperature PTT, tumor cells develop heat stress tolerance due elevated shock protein (HSP) levels, diminishing therapeutic efficacy. Moreover, excessive can trigger inflammatory conditions and promote metastasis. Targeting the glycolytic pathway highly metabolically active offers a promising strategy inducing starvation therapy, capitalizing on their vigorous energy demands amidst rapid proliferation. Here, Initially, we synthesized luminous NIR-II dye, FNF, followed its encapsulation alongside myricetin (My) within amphiphilic polypeptide carriers through self-assembly method. The resulting nanoparticles exhibited excellent imaging capabilities boasted notable photothermal conversion efficiency of 55.58%. Furthermore, Myricetin effectively impeded glucose transport facilitated transporter 1 (GLUT1), curtailing supply cells. This interference disrupted mitochondrial production, leading decreased adenosine triphosphate (ATP) synthesis subsequent downregulation HSP70 expression. By leveraging this approach, which targets HSP expression via GLUT1 inhibition, enhance efficacy PTT while achieving synergistic effect mild starvation.

Language: Английский

Citations

0
Rational design of AIEgens through π-bridge engineering for dual-modal photodynamic and photothermal therapy DOI

Yanwen Liu,

Shaohua Gou, Hongchao Wang

et al.

Bioorganic & Medicinal Chemistry, Journal Year: 2025, Volume and Issue: 119, P. 118081 - 118081

Published: Jan. 23, 2025

Language: Английский

Citations

0
Near-infrared theranostics for brain diseases: Design, engineering, and emerging applications DOI
Jiefei Wang, Yi‐Sheng Liu,

Cai Qi

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 534, P. 216591 - 216591

Published: March 9, 2025

Language: Английский

Citations

0
Polypeptide nanoparticles obstruct glucose supply for NIR-II fluorescence-guided tumor starvation and enhanced mild photothermal therapy DOI
Yating Wang, Yixuan Xu,

Dejia Chen

et al.

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Self-assembled nanoprobes for cancer phototheranostics DOI
Sondavid Nandanwar,

Van Kieu Thuy Nguyen,

Dai Lam Tran

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216643 - 216643

Published: April 18, 2025

Language: Английский

Citations

0