Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(42)
Published: May 28, 2024
Abstract
Excited‐state
intramolecular
proton
transfer
(ESIPT)
molecules,
which
feature
large
Stokes
shifts
to
avoid
self‐absorption,
play
an
essential
role
in
photoluminescent
bioimaging
probes.
Herein,
we
report
the
development
of
ESIPT
molecule
3‐(3‐hydroxypyridin‐2‐yl)isoquinolin‐4‐ol
(
PiQ
).
not
only
undergoes
a
distinct
process
unlike
symmetrical
2,2′‐bipyridyl‐3,3′‐diol
but
also
exhibits
aggregation‐induced
emission
(AIE)
characteristics.
self‐assembles
into
aggregates
with
average
size
241.0±51.9
nm
aqueous
solutions,
leading
significantly
enhanced
photoluminescence.
On
basis
and
AIE
characteristics
,
latter
is
functionalized
hydrogen
peroxide‐responsive
4‐pinacoratoborylbenzyl
group
B
)
carboxylesterase‐responsive
acetyl
A
produce
probe
B−PiQ−A
.
The
potential
for
applications
chemical
sensing
underscored
by
its
efficient
detection
both
endogenous
exogenous
peroxide
living
cells.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(42)
Published: May 28, 2024
Abstract
Excited‐state
intramolecular
proton
transfer
(ESIPT)
molecules,
which
feature
large
Stokes
shifts
to
avoid
self‐absorption,
play
an
essential
role
in
photoluminescent
bioimaging
probes.
Herein,
we
report
the
development
of
ESIPT
molecule
3‐(3‐hydroxypyridin‐2‐yl)isoquinolin‐4‐ol
(
PiQ
).
not
only
undergoes
a
distinct
process
unlike
symmetrical
2,2′‐bipyridyl‐3,3′‐diol
but
also
exhibits
aggregation‐induced
emission
(AIE)
characteristics.
self‐assembles
into
aggregates
with
average
size
241.0±51.9
nm
aqueous
solutions,
leading
significantly
enhanced
photoluminescence.
On
basis
and
AIE
characteristics
,
latter
is
functionalized
hydrogen
peroxide‐responsive
4‐pinacoratoborylbenzyl
group
B
)
carboxylesterase‐responsive
acetyl
A
produce
probe
B−PiQ−A
.
The
potential
for
applications
chemical
sensing
underscored
by
its
efficient
detection
both
endogenous
exogenous
peroxide
living
cells.
