An Automated Electrochemistry Platform for Studying pH-dependent Molecular Electrocatalysis DOI Creative Commons
Michael A. Pence,

Gavin Hazen,

Joaquín Rodríguez‐López

et al.

Published: June 25, 2024

Comprehensive studies of molecular electrocatalysis require tedious titration-type experiments that slow down manual experimentation. We present elab as an automated electrochemical platform designed for electrochemistry uses opensource software to modularly interconnect various commercial instruments, enabling users chain together multiple instruments complex operations. benchmarked the solution handling performance our through gravimetric calibration, acid-base titrations, and voltammetric diffusion coefficient measurements. then used explore TEMPO-catalyzed electrooxidation alcohols, demonstrating platforms capabilities pH-dependent electrocatalysis. performed combined titrations cyclic voltammetry on six different alcohol substrates, collecting 684 voltammograms with 171 conditions over course 16 hours, high throughput in unsupervised experiment. The versatility, transferability, ease implementation promises rapid discovery characterization processes, including mediated energy conversion, fuel valorization, bioelectrochemical sensing, among many applications.

Language: Английский

ORGANA: A robotic assistant for automated chemistry experimentation and characterization DOI
Kourosh Darvish, Marta Skreta, Yuchi Zhao

et al.

Matter, Journal Year: 2024, Volume and Issue: unknown, P. 101897 - 101897

Published: Nov. 1, 2024

Language: Английский

Citations

14

Closed-Loop Navigation of a Kinetic Zone Diagram for Redox-Mediated Electrocatalysis Using Bayesian Optimization, a Digital Twin, and Automated Electrochemistry DOI
Michael A. Pence,

Gavin Hazen,

Joaquín Rodríguez‐López

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Molecular electrocatalysis campaigns often require tuning multiple experimental parameters to obtain kinetically insightful electrochemical measurements, a prohibitively time-consuming task when performing comprehensive studies across catalysts and substrates. In this work, we present an autonomous workflow that combines Bayesian optimization automated electrochemistry perform fully unsupervised cyclic voltammetry (CV) of molecular electrocatalysis. We developed CV descriptors leveraged the conceptual framework EC' (where denotes step followed by catalytic chemical step) kinetic zone diagram enable efficient optimization. The descriptor's effect on performance was evaluated using digital twin our platform, quantifying accuracy obtained values against known ground truth. demonstrated platform experimentally TEMPO-catalyzed ethanol isopropanol electro-oxidation, demonstrating rapid identification conditions in 10 or less iterations through closed-loop workflow. Overall, work highlights application platforms accelerate mechanistic beyond.

Language: Английский

Citations

1

An automated electrochemistry platform for studying pH-dependent molecular electrocatalysis DOI Creative Commons
Michael A. Pence,

Gavin Hazen,

Joaquín Rodríguez‐López

et al.

Digital Discovery, Journal Year: 2024, Volume and Issue: 3(9), P. 1812 - 1821

Published: Jan. 1, 2024

An automated electrochemistry platform designed for molecular electrocatalysis studies.

Language: Английский

Citations

4

PANDA: a self-driving lab for studying electrodeposited polymer films DOI Creative Commons
Harley Quinn,

Gregory A. Robben,

Zhaoyi Zheng

et al.

Materials Horizons, Journal Year: 2024, Volume and Issue: 11(21), P. 5331 - 5340

Published: Jan. 1, 2024

We report the PANDA, a self-driving lab that handles fluids, electrodeposits polymers, and then functionally characterizes result using optics or electrochemistry. As an example application, we perform closed-loop study of electrochromic films.

Language: Английский

Citations

3

The Emergence of Automation in Electrochemistry DOI Creative Commons
Michael A. Pence,

Gavin Hazen,

Joaquín Rodríguez‐López

et al.

Current Opinion in Electrochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 101679 - 101679

Published: March 1, 2025

Language: Английский

Citations

0

Automation in Electrifying Flow Organic Synthesis DOI Creative Commons
Tomas Hardwick, Nisar Ahmed

Tetrahedron Chem, Journal Year: 2024, Volume and Issue: unknown, P. 100105 - 100105

Published: Oct. 1, 2024

Language: Английский

Citations

1

An Automated Electrochemistry Platform for Studying pH-dependent Molecular Electrocatalysis DOI Creative Commons
Michael A. Pence,

Gavin Hazen,

Joaquín Rodríguez‐López

et al.

Published: June 25, 2024

Comprehensive studies of molecular electrocatalysis require tedious titration-type experiments that slow down manual experimentation. We present elab as an automated electrochemical platform designed for electrochemistry uses opensource software to modularly interconnect various commercial instruments, enabling users chain together multiple instruments complex operations. benchmarked the solution handling performance our through gravimetric calibration, acid-base titrations, and voltammetric diffusion coefficient measurements. then used explore TEMPO-catalyzed electrooxidation alcohols, demonstrating platforms capabilities pH-dependent electrocatalysis. performed combined titrations cyclic voltammetry on six different alcohol substrates, collecting 684 voltammograms with 171 conditions over course 16 hours, high throughput in unsupervised experiment. The versatility, transferability, ease implementation promises rapid discovery characterization processes, including mediated energy conversion, fuel valorization, bioelectrochemical sensing, among many applications.

Language: Английский

Citations

1