Oxygen-, Nitrogen-, and Sulfur-Containing Heterocycles: Recent Advances in De Novo Synthesis and Prospect
Organic Process Research & Development,
Journal Year:
2024,
Volume and Issue:
28(8), P. 2988 - 3025
Published: July 13, 2024
Language: Английский
Photochemical Synthesis and Ring‐Opening of Aziridines and Epoxides: State‐of‐the‐Art
ChemPhotoChem,
Journal Year:
2024,
Volume and Issue:
8(9)
Published: May 13, 2024
Abstract
The
development
of
greener
methods
for
the
preparation
three‐membered
rings
has
increased
in
last
decade,
not
only
due
to
their
biological
activity
but
also
ring
strain
those
heterocycles
that
make
them
useful
precursors
more
complex
molecules.
In
this
work,
visible‐light‐promoted
synthesis
and
ring‐opening
aziridines
epoxides,
reported
five
years,
were
reviewed.
Both
homogeneous
heterogeneous
catalysts
discussed
and,
addition,
plausible
mechanism
pathways
highlighted.
Language: Английский
Visible Light‐Induced Copper‐Catalyzed Alkylation/exo‐Cyclization of 1,7‐Dienes with Sulfonium Salts to Access Sulfur‐Containing Polycyclic Compounds
Xin‐Qian Liu,
No information about this author
Jian‐Hong Fan,
No information about this author
Kewen Tang
No information about this author
et al.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 9, 2024
Abstract
A
direct
visible‐light‐promoted
radical‐triggered
tandem
cyclization
of
1,7‐diene
systems
with
cyclic
sulfonium
salts
by
using
copper(I)‐based
complexes
as
photoredox
catalyst
is
developed.
With
this
approach,
a
variety
sulfur‐containing
polycyclic
derivatives
are
prepared
through
alkylation/
6‐exo‐trig
cyclization/
5‐exo‐trig
under
mild
conditions.
In
addition,
the
photoinduced
copper‐catalyzed
ring‐opening
provides
alkyl
radical
intermediates,
which
prefers
addition
to
C−C
double
bond
that
connected
aromatic
ring
rather
than
electron‐deficient
vinyl
in
1,7‐dienes.
Moreover,
oxidation
desired
products
strategy
for
preparation
remote
nitrogen‐fused
substituted
sulfoxide
or
sulfone‐containing
derivatives.
Language: Английский
Photo- and Electro-chemical Strategies for Indazole Synthesis
Tetrahedron Chem,
Journal Year:
2024,
Volume and Issue:
unknown, P. 100116 - 100116
Published: Dec. 1, 2024
The
indazole
core
is
prevalently
found
in
the
structures
of
bioactive
molecules,
demonstrating
promising
potential
medicinal
chemistry
and
drug
discovery,
which
therefore
has
attracted
sustained
attention
from
synthetic
community.
Over
recent
decades,
significant
progress
been
achieved
both
organic
photocatalysis
electrosynthesis,
offering
novel
approaches
for
efficient
sustainable
synthesis
various
functionalized
indazoles.
This
mini-review
highlights
emerging
methodological
advancements
photo-/electro-chemical
two
common
forms
indazole,
namely
1H-
2H-indazoles,
are
classified
by
specific
intramolecular
bond
formation
patterns:
(1)
C-C
formation,
(2)
C-N
(3)
N-N
formation.
reaction
conditions,
representative
scopes,
mechanistic
understandings
these
protocols
emphasized,
to
elucidate
advantages
limitations
current
strategies,
with
an
aim
inspire
future
innovations
that
may
address
challenges
modern
synthesis.Graphical
abstractTo
create
your
abstract,
type
over
instructions
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box
below.
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or
abstract
dimensions
should
not
be
changed
altered.
Language: Английский
Copper and Photocatalytic Synergistic Strategies for Radical Cyclization Reactions
Yunpeng Lu,
No information about this author
Nan‐Nan Dai,
No information about this author
M. Li
No information about this author
et al.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(19), P. 4000 - 4016
Published: July 30, 2024
Abstract
The
rapid
development
of
photo‐synergistic
transition
metal
catalytic
systems
has
provided
a
green
paradigm
to
complement
thermal
methods.
However,
the
most
commonly
used
iridium
or
ruthenium
complexes
involve
expensive
in
nature,
contrast
abundant
copper
elements
earth's
crust,
which
are
highly
valued
for
their
unique
electronic
structure
and
light‐absorbing
properties.
Recently,
application
photocatalytic
synergistic
strategies
radical
cyclization
reactions
progressed
considerably,
leading
renaissance
synthesis
functional
natural
products,
drugs
analogues,
but
summary
work
addressing
this
aspect
not
been
reported.
In
review,
we
briefly
analyze
effect
ligand
choice
on
some
inorganic
salts
even
light
sources.
We
then
summarize
classify
them
into
three
categories,
C,
N
O
radicals,
according
class
central
atom
each
work,
category
will
be
elaborated
turn
from
coordination
via
Cu
catalysts,
direct
other
mode.
For
individual
more
complex
reactions,
mechanisms
explored
discussed.
Language: Английский
Visible‐Light Enabled Synthesis of 1‐Aryl‐3‐Sulfonylmethyl‐1,2,4‐Triazoles by Arylazo Sulfones
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 5, 2024
Abstract
We
present
a
novel
and
highly
efficient
method
for
synthesizing
polyfunctionalized
1,2,4‐triazoles.
This
approach
leverages
visible
light
arylazo
sulfones
in
combination
with
N
‐vinyl
amides,
the
environmentally
friendly
solvent
ethyl
acetate.
Remarkably,
reaction
proceeds
without
need
(photo)catalysts,
ensuring
near‐perfect
atom
economy
producing
only
water
as
by‐product.
exhibits
excellent
functional
group
tolerance
can
be
scaled
both
batch
continuous‐flow
processes.
Language: Английский