Contents list DOI Creative Commons

Lab on a Chip, Journal Year: 2023, Volume and Issue: 23(18), P. 3899 - 3905

Published: Jan. 1, 2023

Permissions Request permissions Contents list Lab Chip, 2023, 23, 3899 DOI: 10.1039/D3LC90082G This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this in other publications without requesting further the RSC, provided that correct acknowledgement given. Read more about how to correctly acknowledge RSC content.

Language: Английский

High-throughput microfluidic systems accelerated by artificial intelligence for biomedical applications DOI Open Access
Jianhua Zhou, Jianpei Dong, Hongwei Hou

et al.

Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(5), P. 1307 - 1326

Published: Jan. 1, 2024

This review outlines the current advances of high-throughput microfluidic systems accelerated by AI. Furthermore, challenges and opportunities in this field are critically discussed as well.

Language: Английский

Citations

20
Droplet microfluidics: unveiling the hidden complexity of the human microbiome DOI

Yibin Xu,

Zhiyi Wang, Caiming Li

et al.

Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The human microbiome is vital for health. Droplet microfluidics offers a versatile toolbox research, enabling single-cell sequencing, cultivation, and functional analyses to deepen our understanding drive innovations.

Language: Английский

Citations

1
Organ-on-a-chip platforms integrated with biosensors for precise monitoring of the cells and cellular microenvironment DOI
Weiyou Yang,

Tengyun Li,

Shufei Liao

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 172, P. 117569 - 117569

Published: Jan. 30, 2024

Language: Английский

Citations

8
Production of bacteriocins by AI: As food preservative DOI
Mudasir Rashid, Amzad Basha Kolar,

S. I. Beema Jainab

et al.

Methods in microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Molecular insights fast-tracked: AI in biosynthetic pathway research DOI
Lijuan Liao,

Mengjun Xie,

Xiaoshan Zheng

et al.

Natural Product Reports, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review explores how AI addresses challenges in biosynthetic pathway research, accelerating the development of bioactive natural products for pharmacology, agriculture, and biotechnology.

Language: Английский

Citations

0
Artificial Intelligence-Assisted Multiparameter Size Discrimination of Silver Nanoparticles through Electrochemical Collision DOI
Ying Xu, Weijian Jiang, Yi‐Yan Bai

et al.

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(16), P. 6195 - 6201

Published: April 12, 2024

Single particle collision is an important tool for size analysis at the individual level; however, due to complex dynamic behaviors of nanoparticles on surface electrode, accuracy discrimination limited. A silver (Ag) nanoparticle (NP) was chosen as research target, and behavior Ag NPs simplified by enhancing adsorption between NP Au ultramicroelectrode (UME) in alkaline media. Immediately after, accurate thermodynamic information single accurately extracted from events, including current intensity, transferred charge, duration time. On basis that there were differences parameters different-sized NPs, multiparameter proposed, which improved compared single-parameter discrimination. More intriguingly, combined with artificial intelligence, a adept processing multidimensional data, first Finally, intelligence-assisted successfully used intelligently distinguish mixed optimal more than 95%. To sum up, method showed excellent ability quickly achieve most level provide effective guidance application nanoparticles.

Language: Английский

Citations

2
Advances in Droplet-Based Microfluidic High-Throughput Screening Based on Ultraviolet, Visible and Fluorescent Spectroscopy DOI Open Access

Shunyang Hu,

Bangxu Wang,

Qing Luo

et al.

Published: Dec. 26, 2023

Genetic engineering and directed evolution are effective methods to address the low yield poor industrialization level of microbial target products. The current research focus is on how efficiently rapidly screen beneficial mutants from constructed large-scale mutation libraries. Traditional screening such as plate well severely limited in their development application due efficiency high costs. In past decade, microfluidic technology has become an important high-throughput its fast speed, cost, automation, throughput, it developed rapidly. Droplet-based been widely used various fields strain/enzyme activity screening, pathogen detection, single-cell analysis, drug discovery, chemical synthesis, applied industries materials, food, chemicals, textiles, biomedicine. particular, field enzyme research, droplet-based shown excellent performance discovering enzymes with new functions, improved catalytic or stability, acid-base tolerance, etc. Currently, achieved glycosidase, lipase, peroxidase, protease, amylase, oxidase, transaminase, detection products riboflavin, coumarin, 3-dehydroquinate, lactic acid, ethanol. This article reviews microfluidics a strategies based UV, visible, fluorescence spectroscopy, including labeled optical signal label-free electrochemical mass spectrometry, Raman nuclear magnetic resonance, Furthermore, progress trends modification strain also introduced.

Language: Английский

Citations

2
Advances in Droplet-Based Microfluidic High-Throughput Screening of Engineered Strains and Enzymes Based on Ultraviolet, Visible, and Fluorescent Spectroscopy DOI Creative Commons

Shunyang Hu,

Bangxu Wang,

Qing Luo

et al.

Fermentation, Journal Year: 2023, Volume and Issue: 10(1), P. 33 - 33

Published: Dec. 30, 2023

Genetic engineering and directed evolution are effective methods for addressing the low yield poor industrialization level of microbial target products. The current research focus is on how to efficiently rapidly screen beneficial mutants from constructed large-scale mutation libraries. Traditional screening such as plate well-plate severely limited in their development application due efficiency high costs. In past decade, microfluidic technology has become an important high-throughput its fast speed, cost, automation, throughput, it developed rapidly. Droplet-based been widely used various fields, strain/enzyme activity screening, pathogen detection, single-cell analysis, drug discovery, chemical synthesis, applied industries those involving materials, food, chemicals, textiles, biomedicine. particular, field enzyme research, droplet-based shown excellent performance discovering enzymes with new functions well improved catalytic or stability, acid-base tolerance, etc. Currently, achieved glycosidase, lipase, peroxidase, protease, amylase, oxidase, transaminase detection products riboflavin, coumarin, 3-dehydroquinate, lactic acid, ethanol. This article reviews microfluidics a strategies based UV, visible, fluorescence spectroscopy, including labeled optical signal label-free electrochemical mass spectrometry, Raman nuclear magnetic resonance, Furthermore, progress trends modification strain also introduced.

Language: Английский

Citations

2
Microfluidic chips as drug screening platforms DOI

I. G. Kim,

Jinho Kwon,

Junyeol Rhyou

et al.

JMST Advances, Journal Year: 2024, Volume and Issue: 6(2), P. 155 - 160

Published: June 1, 2024

Language: Английский

Citations

0
Application of Microfluidics in Drug Development DOI
Maryam Parhizkar, Fanjin Wang,

Tsitouridou Anna

et al.

AAPS introductions in the pharmaceutical sciences, Journal Year: 2024, Volume and Issue: unknown, P. 293 - 312

Published: Jan. 1, 2024

Language: Английский

Citations

0