Gold-nanoparticle associated Deep Eutectic Solution mediates early bio detection of Ovarian Cancer
International Journal of Nanoelectronics and Materials (IJNeaM),
Journal Year:
2025,
Volume and Issue:
18(1), P. 36 - 46
Published: Jan. 10, 2025
Gold
nanoparticles
(AuNPs)
have
indeed
been
extensively
researched
in
biological
and
photothermal
therapy
applications
recent
years.
This
study
aims
to
enhance
the
sensitivity
of
biosensors
for
early
detection
ovarian
cancer
biomarkers
by
investigating
efficacy
DES-mediated
surface
functionalization
AuNPs.
Additionally,
impact
DES
on
stability
dispersion
AuNPs
SiO2
support
is
assessed
optimize
sensor
performance.
A
simple
synthesis
method
efficient
amine
silicon
dioxide
(SiO2)
incorporate
tiny
antibody
biosensors.
Physical
characterization
[Scanning
Electron
Microscope
(SEM),
Ultraviolet-Visible
Spectrophotometer
(UV-Vis),
Fourier
Transform
Infrared
Spectroscopy
(FTIR),
3D
Profiler]
electrical
(Keithley)
done
determine
modified
IDE
surface.
SEM
analysis
indicated
resultant
truncated
spherical
shapes.
There
just
a
peak
recorded
UV-Vis
at
504-540
nm
with
due
formation
monodispersed
When
conjugation
samples
measured,
curves
are
identical
form,
highest
after
has
remained
230
but
SPR
absorption
becomes
narrower
moves
toward
greater
wavelengths,
indicating
between
molecules.
Furthermore,
when
conjugated
AuNPs,
3-Aminopropyltriethoxysilane
(APTES),
antibody,
protein,
peaks
gradually
increased
became
narrower,
where
O-H
3280
cm-1,
C-H
2809
cm-1
2933
CH2
1448
CH3
1268
C-OH
1048
1110
C-N+
844
as
analyzed
FTIR.
Moreover,
it
can
be
observed
that
profilometer
revealed
few
red-colored
areas,
which
portion
protrudes
from
Based
findings,
possible
infer
this
immunosensor
does
prospective
used
clinical
investigations
precise
or
other
biomarkers.
The
capacitance,
transmittance,
resistivity
profiles
biosensor
clearly
distinguished
immobilization
affinity
binding.
presence
synthetic
approach
possibility
supporting
different
metal
potential
platform
applications.
Language: Английский
Selenium, Silver, and Gold Nanoparticles: Emerging Strategies for Hepatic Oxidative Stress and Inflammation Reduction
Karthik K Karunakar,
No information about this author
Binoy Varghese Cheriyan,
No information about this author
D. Suresh Babu
No information about this author
et al.
Nano TransMed,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100085 - 100085
Published: May 1, 2025
Language: Английский
Carriers for hydrophobic drug molecules: lipid-coated hollow mesoporous silica particles, and the influence of shape and size on encapsulation efficiency
Sumiya Iqbal,
No information about this author
T. Schneider,
No information about this author
Trương Thanh Tùng
No information about this author
et al.
Nanoscale,
Journal Year:
2024,
Volume and Issue:
16(23), P. 11274 - 11289
Published: Jan. 1, 2024
Hydrophobic
drugs,
while
designed
to
interact
with
specific
receptors
or
enzymes
located
in
lipid-rich
cell
membranes,
often
face
challenges
of
limited
bioavailability
and
insufficient
circulation
time
due
their
insolubility
aqueous
environments.
One
plausible
pathway
increase
blood
is
load
these
drugs
into
biocompatible
hydrophilic
carriers
enhance
uptake.
In
this
study,
mesoporous
silica
(mSiO2)
nanocarriers
various
morphologies
(including
cubes,
capsules,
spheres)
were
synthesized.
These
then
surface-functionalized
alkyl
chain
hydrocarbons,
specifically
octadecyl-trimethoxysilane,
(OCH3)3Si(CH2)17CH3,
render
them
hydrophobic.
The
resulting
(((OCH3)3Si(CH2)17CH3)@mSiO2)
showed
up
80%
uptake
for
hydrophobic
drugs.
However,
a
significant
drawback
was
observed
as
most
the
prone
uncontrollable
release
within
6
h.
This
challenge
premature
drug
successfully
mitigated
by
effectively
sealing
drug-loaded
pH-sensitive
lipid
overlayer.
lipid-coated
prolonged
containment
sustained
72
h,
compared
h
uncoated
nanocarriers,
thereby
facilitating
longer
times.
Moreover,
shape
size
found
influence
both
entrapment
capacity
behavior
cubic
forms
exhibiting
superior
loading
higher
surface
area
porosity.
Additionally,
it
that
molecular
weight
chemical
structure
molecules
played
crucial
role
determining
profiles.
Furthermore,
different
on
cytotoxicity
immune
cells
elucidated.
findings
underscore
importance
nanocarrier
morphology
properties
capacities
controlled
profiles,
designing
delivery
systems
tailored
Language: Английский
Advances in nephroprotection: the therapeutic role of selenium, silver, and gold nanoparticles in renal health
Karthik K Karunakar,
No information about this author
Elizabeth Rani Edwin,
No information about this author
Meenaloshini Gopalakrishnan
No information about this author
et al.
International Urology and Nephrology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 23, 2024
Language: Английский
Solvent-based dual detection of Hg2+ and Cr3+ ions by polyvinylpyrrolidone stabilized silver nanoparticles as colorimetric sensor
A. Koushalya,
No information about this author
K. Anitha
No information about this author
Optical Materials,
Journal Year:
2024,
Volume and Issue:
unknown, P. 116330 - 116330
Published: Oct. 1, 2024
Language: Английский
A functional eutectogel based on ultrahigh–molecular weight polymers: Physical entanglements in deep eutectic solvent
Journal of Colloid and Interface Science,
Journal Year:
2024,
Volume and Issue:
683, P. 610 - 619
Published: Dec. 18, 2024
Language: Английский
Morphology engineering of inorganic nanocrystals with deep eutectic solvents (DESs): Current developments and future prospects
Coordination Chemistry Reviews,
Journal Year:
2024,
Volume and Issue:
527, P. 216406 - 216406
Published: Dec. 25, 2024
Language: Английский
Strategic electrochemical oxidation of vinblastin sulfate (an anticancer drug) via PVP-functionalized strontium oxide nanoparticles
Sana-ul-Nisa Lanjar,
No information about this author
Amber R. Solangi,
No information about this author
Nahjul Batool
No information about this author
et al.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(43), P. 31387 - 31397
Published: Jan. 1, 2024
Graphical
layout
for
the
synthesis
of
PVP-SrO
NPs.
Language: Английский