Nanoformulations in Pharmaceutical and Biomedical Applications: Green Perspectives

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(11), P. 5842 - 5842

Published: May 27, 2024

This study provides a brief discussion of the major nanopharmaceuticals formulations as well impact nanotechnology on future pharmaceuticals. Effective and eco-friendly strategies biofabrication are also highlighted. Modern approaches to designing pharmaceutical nanoformulations (e.g., 3D printing, Phyto-Nanotechnology, Biomimetics/Bioinspiration, etc.) outlined. paper discusses need use natural resources for “green” design new with therapeutic efficiency. Nanopharmaceuticals research is still in its early stages, preparation nanomaterials must be carefully considered. Therefore, safety long-term effects not overlooked. The testing represents an essential point their further applications. Vegetal scaffolds obtained by decellularizing plant leaves represent valuable, bioinspired model nanopharmaceutical that avoids using animals. Nanoformulations critical various fields, especially pharmacy, medicine, agriculture, material science, due unique properties advantages over conventional allows improved solubility, bioavailability, targeted drug delivery, controlled release, reduced toxicity. have transitioned from experimental stages being vital component clinical practice, significantly improving outcomes medical fields cancer treatment, infectious diseases, neurological disorders, personalized advanced diagnostics. Here key points highlighting importance. significant challenges, opportunities, directions mentioned final section.

Language: Английский

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Coordination bonded stimuli-responsive drug delivery system of chemical actives with metal in pharmaceutical applications

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 510, P. 215851 - 215851

Published: April 8, 2024

Language: Английский

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Metal‐Organic Frameworks (MOFs): Classification, Synthesis, Modification, and Biomedical Applications

Small, Journal Year: 2024, Volume and Issue: 20(47)

Published: Aug. 16, 2024

Abstract Metal‐organic frameworks (MOFs) are a new variety of solid crystalline porous functional materials. As an extension inorganic materials, it has made important progress in preparation and application. MOFs widely used various fields such as gas adsorption storage, drug delivery, sensing, biological imaging due to their high specific surface area, porosity, adjustable pore size, abundant active sites, modification by introducing groups. In this paper, the types classified, synthesis methods mechanisms materials summarized. Finally, application prospects challenges metal‐organic framework biomedical field discussed, hoping promote multidisciplinary fields.

Language: Английский

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A comprehensive study on RSM optimization of the influencing variables on loading/releasing of ciprofloxacin onto/from magnetic iron nanoparticles

Solid State Sciences, Journal Year: 2024, Volume and Issue: 154, P. 107584 - 107584

Published: May 28, 2024

Language: Английский

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Research progress of copper-based metal–organic frameworks for cancer diagnosis and therapy

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 514, P. 215943 - 215943

Published: May 14, 2024

Language: Английский

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Chromium-functionalized metal-organic frameworks as highly sensitive, dual-mode sensors for real time and rapid detection of dopamine

Talanta, Journal Year: 2025, Volume and Issue: 289, P. 127771 - 127771

Published: Feb. 23, 2025

Language: Английский

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Iron‐MOFs for Biomedical Applications

Advanced Healthcare Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 10, 2024

Over the past two decades, iron-based metal-organic frameworks (Fe-MOFs) have attracted significant research interest in biomedicine due to their low toxicity, tunable degradability, substantial drug loading capacity, versatile structures, and multimodal functionalities. Despite great potential, transition of Fe-MOFs-based composites from laboratory clinical products remains challenging. This review evaluates key properties that distinguish Fe-MOFs other MOFs highlights recent advances synthesis routes, surface engineering, shaping technologies. In particular, it focuses on applications biosensing, antimicrobial, anticancer therapies. addition, emphasizes need develop scalable, environmentally friendly, cost-effective production methods for additional meet specific requirements various biomedical applications. ability combine therapies, hurdles still remain, including a deeper understanding therapeutic mechanisms potential risks resistance overdose. Systematically addressing these challenges could significantly enhance prospects potentially facilitate integration into mainstream practice.

Language: Английский

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Application of nanoscale metal-organic coordination polymers in cancer therapy

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 154342 - 154342

Published: July 27, 2024

Language: Английский

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Functionalized ZIF-8 as a versatile platform for drug delivery and cancer therapy: strategies, challenges and prospects

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review discusses the functionalization strategies of ZIF-8 and challenges future developments in ZIF-8-based platforms for drug delivery cancer therapy.

Language: Английский

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Metal-organic frameworks-engineered reactive-oxygen catalytic materials: Enzyme-mimicking coordinations, structure evolutions, and biotherapeutic applications

Materials Today, Journal Year: 2024, Volume and Issue: 78, P. 142 - 180

Published: July 20, 2024

Language: Английский

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