Ammonium Sensing Patch with Ultrawide Linear Range and Eliminated Interference for Universal Body Fluids Analysis DOI Creative Commons

Mingli Huang,

Xiaohao Ma, Zongze Wu

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 17(1)

Published: Dec. 23, 2024

Abstract Ammonium level in body fluids serves as one of the critical biomarkers for healthcare, especially those relative to liver diseases. The continuous and real-time monitoring both invasive non-invasive manners is highly desired, while ammonium concentrations vary largely different fluids. Besides, sensing reliability based on ion-selective biosensors can be significantly interfered by potassium ions. To tackle these challenges, a flexible biocompatible patch wireless was reported with an ultrawide linear range universal including blood, tears, saliva, sweat urine. as-prepared sensors deliver reliable sensitivity 58.7 mV decade −1 1–100 mM desirable selectivity coefficient 0.11 interference ions, attributed cross-calibration within array. sensor’s biocompatibility validated cell growth sensor surface (> 80%), hemolysis rates (< 5%), negligible cellular inflammatory responses weight changes mice implanted sensors. Such open up new possibility compatible biomarker analysis via versatile approaches.

Language: Английский

A Fully Printable and Integrated System with Long-Term Stability for Versatile and Multimodal Perspiration Tracking DOI

Kemeng Zhou,

Ruochen Ding, Wenhao Ye

et al.

Nano Letters, Journal Year: 2024, Volume and Issue: 24(47), P. 15092 - 15100

Published: Oct. 25, 2024

Real-time and continuous monitoring of physiological status via noninvasive sweat sensing shows promise for personalized healthcare fitness management. However, the largely varied perspiration rates in different body statuses introduce challenges effective collection accurate sensing. Herein, a fully printable strategy was developed to realize integrated patches wireless biomarker levels with desirable stability versatility. The calcium sensors modified ion-selective membranes displayed an ultrawide linear range 0.1-100 mM long-term minimized drift down 0.083 mV/h around 40 h. Moreover, microfluidic channels versatile configurations were capable minimum rate 0.5 μL/min large storage volume up 200 μL. as-proposed platforms provide high compatibility sensor integration achieve tracking comprehensive health monitoring.

Language: Английский

Citations

2
Evolutionary Approximation of Ternary Neurons for On-sensor Printed Neural Networks DOI
Vojtěch Mrázek, Argyris Kokkinis, P. Papanikolaou

et al.

Published: Oct. 27, 2024

Printed electronics offer ultra-low manufacturing costs and the potential for on-demand fabrication of flexible hardware. However, significant intrinsic constraints stemming from their large feature sizes low integration density pose design challenges that hinder practicality. In this work, we conduct a holistic exploration printed neural network accelerators, starting analog-to-digital interface - major area power sink sensor processing applications extending to networks ternary neurons implementation. We propose bespoke using approximate popcount popcount-compare units, developed through multi-phase evolutionary optimization approach interfaced with sensors via customizable analog-to-binary converters. Our evaluation results show presented designs outperform state art, achieving at least 6x improvement in 19x power. To our knowledge, they represent first open-source digital classifiers capable operating existing energy harvesters.

Language: Английский

Citations

0
Feasibility and performance of TiCN-based patch antennas for microwave antenna applications DOI
Mohamad Ashry Jusoh,

N. I. E. Pamin,

Nur Iffah Zulaikha Azman

et al.

Journal of Materials Science Materials in Electronics, Journal Year: 2024, Volume and Issue: 35(22)

Published: Aug. 1, 2024

Language: Английский

Citations

0
Epidermal Secretion-purified Biosensing Patch with Hydrogel Sebum Filtering Membrane and Unidirectional Flow Microfluidic Channels DOI
Haijun Yu, Ziyu Zhang, Yuqing Shi

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 313, P. 122810 - 122810

Published: Sept. 3, 2024

Language: Английский

Citations

0
Ammonium Sensing Patch with Ultrawide Linear Range and Eliminated Interference for Universal Body Fluids Analysis DOI Creative Commons

Mingli Huang,

Xiaohao Ma, Zongze Wu

et al.

Nano-Micro Letters, Journal Year: 2024, Volume and Issue: 17(1)

Published: Dec. 23, 2024

Abstract Ammonium level in body fluids serves as one of the critical biomarkers for healthcare, especially those relative to liver diseases. The continuous and real-time monitoring both invasive non-invasive manners is highly desired, while ammonium concentrations vary largely different fluids. Besides, sensing reliability based on ion-selective biosensors can be significantly interfered by potassium ions. To tackle these challenges, a flexible biocompatible patch wireless was reported with an ultrawide linear range universal including blood, tears, saliva, sweat urine. as-prepared sensors deliver reliable sensitivity 58.7 mV decade −1 1–100 mM desirable selectivity coefficient 0.11 interference ions, attributed cross-calibration within array. sensor’s biocompatibility validated cell growth sensor surface (> 80%), hemolysis rates (< 5%), negligible cellular inflammatory responses weight changes mice implanted sensors. Such open up new possibility compatible biomarker analysis via versatile approaches.

Language: Английский

Citations

0