Exploiting the nanotechnological approaches for traditional Chinese medicine in childhood rhinitis: A review of future perspectives DOI Creative Commons
Yao Zhang,

Haicheng Dong,

Yu Zhu

et al.

Nanotechnology Reviews, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Childhood rhinitis is an inflammatory condition affecting the nasal mucosa of children worldwide. The physical, social, and cognitive performance affected by chronic symptoms childhood rhinitis. Effective treatment essential to avoid long-term effects on children’s lifestyles well-being. Traditional Chinese medicine (TCM) has been used treat prevent several illnesses, it plays a crucial role in healthcare rehabilitation. TCM traditionally holistically However, drawbacks TCMs, such as their poor water solubility, low bioavailability, single-use, targeting ability, severely restrict use. In recent years, nanotechnology for various drugs improve therapeutic effectiveness reduce associated adverse effects. Nanomaterials formulations are synthesized be compatible with herbal extracts sustain active component qualities. Nanocarrier-based drug delivery improves circulation time, targeted distribution, resolving administration issues. This review assesses innovative combination developments rhinitis, providing insights into novel approaches. also provides significant potential this multidisciplinary approach transform techniques offers road map future research initiatives promising sector.

Language: Английский

Curcumin-loaded polymeric nanomaterials as a novel therapeutic strategy for Alzheimer's disease: A comprehensive review DOI
Jinjin Pei, Chella Perumal Palanisamy, Prabhu Manickam Natarajan

et al.

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 99, P. 102393 - 102393

Published: June 24, 2024

Language: Английский

Citations

10
Enhancing the Efficacy of Active Pharmaceutical Ingredients in Medicinal Plants through Nanoformulations: A Promising Field DOI Creative Commons

Yuhao Chen,

Yuying Tang, Yuanbo Li

et al.

Nanomaterials, Journal Year: 2024, Volume and Issue: 14(19), P. 1598 - 1598

Published: Oct. 3, 2024

This article explores the emerging field of nanomedicine as a drug delivery system, aimed at enhancing therapeutic efficacy active pharmaceutical ingredients in medicinal plants. The traditional methods applying plants present several limitations, such low bioavailability, poor solubility, challenges accurately controlling dosage, and inadequate targeting. Nanoformulations represent an innovative approach preparation that employs nanotechnology to produce nanoscale particles or carriers, which are designed overcome these limitations. offer distinct advantages, significantly solubility bioavailability drugs, particularly for poorly soluble components These formulations effectively enhance thereby facilitating better absorption utilization by human body, turn improves efficacy. Furthermore, enables targeted delivery, ensuring precise administration lesion site minimizing side effects on healthy tissues. Additionally, nanoformulations can regulate release rates, extend duration action, stability treatment effects. However, certain limitations potential risks; their safety require further investigation, regarding toxicity with long-term use. Nevertheless, nanomaterials demonstrate substantial augmenting plants, offering novel approaches methodologies development application.

Language: Английский

Citations

6
Application and Development of Nanotechnology in Traditional Chinese Acupuncture in Recent 20 Years: A Comprehensive Review DOI
Lisha Liu, Xinzi Hu,

Yilin Su

et al.

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Acupuncture, rooted in Traditional Chinese Medicine (TCM), serves as a complementary and alternative therapeutic modality that involves the insertion of needles into specific body points to stimulate treat variety conditions. Over time, acupuncture has garnered global acceptance, progressively addressing an increasing spectrum medical disorders. The integration nanotechnology holds considerable potential improve drug delivery efficacy broaden scope acupuncture's applications, providing novel opportunities for investigating underlying principles meridians acupoints. A bibliometric analysis application over past two decades (2004-2024) highlights emerging research trends focal field. This article provides overview history, biological mechanisms, preparation methods, clinical status nanoacupuncture, with focus on analyzing applications nanoacupuncture technology. Nanotechnology enables visualization imaging acupoints, facilitating deeper understanding physiological mechanisms behind effects. Modified incorporating can serve dual purposes: functioning sensors real-time monitoring various parameters, thereby supporting disease diagnosis enhancing through specialized interventions. Furthermore, nanotechnology-enhanced act platforms targeted working tandem responsive nanoparticles treatment. Despite its promising applicability, faces inherent limitations challenges must be addressed.

Language: Английский

Citations

0
Advances on Delivery System of Active Ingredients of Dried Toad Skin and Toad Venom DOI Creative Commons
Dan Zhang,

Bingtao Zhai,

Jing Sun

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 7273 - 7305

Published: July 1, 2024

Abstract: Dried toad skin (TS) and venom (TV) are the dried of Bufo bufo gargarizans Cantor melanostictus Schneider , which remove internal organs white secretions retroauricular glands. Since 2005, cinobufacini preparations have been approved by State Food Drug Administration for use as adjuvant therapies in treatment various advanced cancers. Meanwhile, bufalenolides has identified main component TS/TV, exhibiting antitumor activity, inducing apoptosis cancer cells inhibiting cell proliferation or metastasis through a variety signaling pathways. However, clinical agents frequently face limitations such inherent toxicity at high concentrations insufficient tumor targeting. Additionally, development utilization these active ingredients hindered poor water solubility, low bioavailability, rapid clearance from bloodstream. To address challenges, design targeted drug delivery system (TDDS) aims to enhance improve targeting within body, increase efficacy, reduce adverse reactions. This article reviews TDDS their components, including passive, active, stimuli-responsive TDDS, provide reference advancing use. Keywords: skin, venom, system, passive targeted,

Language: Английский

Citations

2
Exploiting the nanotechnological approaches for traditional Chinese medicine in childhood rhinitis: A review of future perspectives DOI Creative Commons
Yao Zhang,

Haicheng Dong,

Yu Zhu

et al.

Nanotechnology Reviews, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract Childhood rhinitis is an inflammatory condition affecting the nasal mucosa of children worldwide. The physical, social, and cognitive performance affected by chronic symptoms childhood rhinitis. Effective treatment essential to avoid long-term effects on children’s lifestyles well-being. Traditional Chinese medicine (TCM) has been used treat prevent several illnesses, it plays a crucial role in healthcare rehabilitation. TCM traditionally holistically However, drawbacks TCMs, such as their poor water solubility, low bioavailability, single-use, targeting ability, severely restrict use. In recent years, nanotechnology for various drugs improve therapeutic effectiveness reduce associated adverse effects. Nanomaterials formulations are synthesized be compatible with herbal extracts sustain active component qualities. Nanocarrier-based drug delivery improves circulation time, targeted distribution, resolving administration issues. This review assesses innovative combination developments rhinitis, providing insights into novel approaches. also provides significant potential this multidisciplinary approach transform techniques offers road map future research initiatives promising sector.

Language: Английский

Citations

0