Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(11), P. 2440 - 2446
Published: Jan. 1, 2023
A
novel
approach
for
the
production
of
halogen
cations
through
reaction
halogens
with
silver
ions
is
described
in
this
paper.
On
basis,
regioselective
synthesis
3-haloquinolines
and
3-halospirocyclohexadienones
realized
solvent
regulation.
The
gram-scale
compatibility
complex
substrates
demonstrate
synthetic
potential
protocol,
which
will
be
an
appealing
strategy
organic
synthesis.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(10), P. 6759 - 6769
Published: April 29, 2024
Electrochemical
C–H
mono/multi-bromination
regulation
of
N-sulfonylanilines
on
the
cost-effective
CF
electrode
is
described.
This
reaction
proceeds
smoothly
under
mild
conditions
with
a
broad
substrate
scope,
affording
diverse
mono/multi-brominated
anilines
in
moderate
to
good
yields.
Mechanism
study
reveals
that
this
transformation
involves
anodic
oxidation,
aromatic
electrophilic
substitution,
and
deprotonation.
Preliminary
electroactive
molecule
screening
results
its
prospective
application
MBs
for
electrochemical
biosensors.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 25, 2024
Herein,
we
describe
the
investigation
of
electrochemical
bromination
electron-rich
arenes
in
a
200%
cell.
For
this
application,
at
first,
influence
an
excess
supporting
electrolyte
(Bu
The
bromination
of
α-oxo
ketene
dithioacetals
using
KBr/H2O2,
catalyzed
by
Curvularia
inaequalis
vanadium
chloroperoxidase
(CiVCPO),
has
been
successfully
demonstrated.
A
comparative
study
enzymatic
processes
"on
water"
versus
"in
water",
2
wt%
the
surfactant
TPGS-750-M
revealed
that
in-water
protocol
not
only
provides
higher
yields
but
also
accommodates
a
broader
substrate
scope.
This
method
in
an
aqueous
micellar
medium
enabled
preparation
brominated
fair
to
excellent
(23
examples).
In
system,
concentration
was
increased
up
50
mM,
and
amounts
brominating
agents
KBr
H2O2
were
reduced
approximately
2.0
equivalents
without
compromising
efficiency.
Notably,
this
process
allows
for
gram-scale
high
yields.
Key
advantages
include
its
benign
eco-friendly
nature,
use
water
as
green
solvent,
potential
large-scale
production
dithioacetals.
Organic & Biomolecular Chemistry,
Journal Year:
2023,
Volume and Issue:
21(11), P. 2440 - 2446
Published: Jan. 1, 2023
A
novel
approach
for
the
production
of
halogen
cations
through
reaction
halogens
with
silver
ions
is
described
in
this
paper.
On
basis,
regioselective
synthesis
3-haloquinolines
and
3-halospirocyclohexadienones
realized
solvent
regulation.
The
gram-scale
compatibility
complex
substrates
demonstrate
synthetic
potential
protocol,
which
will
be
an
appealing
strategy
organic
synthesis.
