Asymmetric 1,4-Reduction of Pyrano[2,3-b]indoles with Hantzsch Ester by Chiral Phosphoric Acid DOI

Junyan Zhao,

Man Wang,

Ran Song

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(36), P. 7520 - 7524

Published: Sept. 4, 2024

A highly regioselective and enantioselective transfer hydrogenation of pyrano[2,3-

Language: Английский

The Diversity and Evolution of Chiral Brønsted Acid Structures DOI Creative Commons
Jasemine Handjaya,

Niraja Patankar,

Jolene P. Reid

et al.

Chemistry - A European Journal, Journal Year: 2024, Volume and Issue: 30(46)

Published: May 6, 2024

The chemical space of chiral Brønsted acid catalysts is defined by quantity and complexity, reflecting the diverse synthetic challenges confronted innovative molecular designs introduced. Here, we detail how this successful outcome a powerful demonstration benefits utilizing both local structure searches comprehensive understanding catalyst performance for effective efficient exploration properties. In concept article provide an evolutionary overview field summarizing approaches to optimization, resulting structures, functions.

Language: Английский

Citations

1
General and Versatile Synthesis of Highly Recyclable Chiral Phosphoric Acid Organocatalysts DOI Creative Commons
Aitor Maestro, Sándor B. Ötvös, Gerald Auer

et al.

Published: July 29, 2024

The development of recyclable catalysts has gained more attention in recent years order to minimize the environmental effect and overall cost catalytic processes. Some most broadly used chiral organocatalysts are BINOL-derived phosphoric acids, making it necessary develop efficient recycling strategies. While literature reports require up 13 synthetic steps access here we report a general concise 9-step approach anthracene decorated heterogeneous acids (PS-Anth), which have shown high performance either batch or continuous flow without observing catalyst degradation.

Language: Английский

Citations

1
Catalytic enantioselective synthesis of 2-pyrazolines via one-pot condensation/6π-electrocyclization: 3,5-bis(pentafluorosulfanyl)-phenylthioureas as powerful hydrogen bond donors DOI Creative Commons

Moises A. Romero Reyes,

Subhradeep Dutta,

Minami Odagi

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(37), P. 15456 - 15462

Published: Jan. 1, 2024

A new conjugate-base-stabilized carboxylic acid containing a 3,5-bis(SF 5 )phenylthiourea functionality catalyses challenging one-pot condensations/6π-electrocyclizations of hydrazines and α,β-unsaturated ketones.

Language: Английский

Citations

1
General and versatile synthesis of highly recyclable chiral phosphoric acid organocatalysts DOI
Aitor Maestro, Sándor B. Ötvös, Gerald Auer

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(20), P. 5901 - 5907

Published: Jan. 1, 2024

The development of recyclable catalysts has gained more attention in recent years order to minimize the environmental effect and overall cost catalytic processes. Some most broadly used chiral organocatalysts are BINOL-derived phosphoric acids, making it necessary develop efficient recycling strategies. While literature reports require up 13 synthetic steps access here we report a general concise 9-step approach anthracene decorated heterogeneous acids (PS-Anth), which have shown high performance either batch or continuous flow without observing catalyst degradation.

Language: Английский

Citations

1
Asymmetric 1,4-Reduction of Pyrano[2,3-b]indoles with Hantzsch Ester by Chiral Phosphoric Acid DOI

Junyan Zhao,

Man Wang,

Ran Song

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(36), P. 7520 - 7524

Published: Sept. 4, 2024

A highly regioselective and enantioselective transfer hydrogenation of pyrano[2,3-

Language: Английский

Citations

1