Sequential regioselective arylation of pyrazolones with diaryliodonium salts DOI
Wenbo Liao,

Hairui Du,

M. H. Chen

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 22(4), P. 708 - 713

Published: Dec. 21, 2023

The introduction of aromatic substituents into organic compounds significantly alters their physical and chemical characteristics. Yet, achieving precise control over the site-selectivity arylation continues to pose a considerable challenge. We present here controllable method for site-selective mono-, di-, triarylation pyrazolone with diaryliodonium salts. showcases robustness, flexibility, excellent compatibility broad range functional groups. It enables both site number aryl additions. Specifically, three four substitutable positions in can be selectively arylated, effectively producing products under controlled conditions. Additionally, supports one-pot sequential arylation, leading an array diverse substituents. Control experiments revealed specific conditions each reaction step.

Language: Английский

C(sp3)–H cyclizations of 2-(2-vinyl)phenoxy-tert-anilines DOI Creative Commons
Petra Dunkel, Dóra Bogdán,

Ruth Deme

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(24), P. 16784 - 16800

Published: Jan. 1, 2024

Cyclizations of 2-(2-vinyl)phenoxy- tert -anilines under thermal conditions yield oxazonine or octahydro-dipyrroloquinoline products. The transformations can be considered as further extensions [1, n ]-H transfer and cyclization tertiary anilines.

Language: Английский

Citations

1
Sequential regioselective arylation of pyrazolones with diaryliodonium salts DOI
Wenbo Liao,

Hairui Du,

M. H. Chen

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 22(4), P. 708 - 713

Published: Dec. 21, 2023

The introduction of aromatic substituents into organic compounds significantly alters their physical and chemical characteristics. Yet, achieving precise control over the site-selectivity arylation continues to pose a considerable challenge. We present here controllable method for site-selective mono-, di-, triarylation pyrazolone with diaryliodonium salts. showcases robustness, flexibility, excellent compatibility broad range functional groups. It enables both site number aryl additions. Specifically, three four substitutable positions in can be selectively arylated, effectively producing products under controlled conditions. Additionally, supports one-pot sequential arylation, leading an array diverse substituents. Control experiments revealed specific conditions each reaction step.

Language: Английский

Citations

1