Green light-mediated dual eosin Y/PdII-catalyzed C(sp2)–H arylation of N–H unprotected 2-arylquinazolinones DOI
Shuvam Mondal, Ranjan Jana

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(27), P. 5540 - 5545

Published: Jan. 1, 2024

An eosin Y/Pd II dual catalytic highly regio- and chemoselective C(sp 2 )–H monoarylation of N–H unprotected 2-phenyl quinazolinones with diazonium salts under visible light irradiation is disclosed.

Language: Английский

Transition Metal‐Catalyzed Direct Functionalization of Carbazoles DOI
Vikash Kumar,

S. Sudharsan,

Lusina Mantry

et al.

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Abstract Carbazoles are an important class of nitrogen‐containing heterocycles found in diverse natural products, bioactive molecules, and functional materials. Their broader applications have driven extensive research into their synthesis functionalization. Among various approaches, transition metal‐catalyzed C−H activation has emerged as a powerful tool for direct functionalization, offering regioselectivity, efficiency, sustainability. This review comprehensively summarizes advancements functionalization carbazoles. Various catalytic systems employing palladium, ruthenium, rhodium, nickel, cobalt, copper, iron enabled alkylation, alkenylation, acylation, arylation, alkynylation, heteroatom incorporation These methodologies late‐stage diversification opened avenues accessing structurally complex carbazole derivatives with tailored properties. The aims to provide comprehensive guide researchers exploring via activation, highlighting key mechanistic insights, scope, emerging trends this field.

Language: Английский

Citations

0
Nickel-Catalyzed Cross-Coupling of Aryl Diazonium Salts with Aryl Bromides DOI
Guofu Zhang,

Yu Fu,

Jicong Xiang

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(31), P. 6687 - 6691

Published: July 26, 2024

Herein, we present a one-pot method for the direct cross-coupling of aryl diazonium salts and bromides in an economical way that avoids use sensitive organometallic reagents. The reaction is accomplished with assistance nickel catalysts, ligands, magnesium turnings, lithium chloride, triethylamine, avoiding pre-activated

Language: Английский

Citations

1
Palladium‐Catalyzed Direct Alkynylation of Carbazoles with Alkynyl Bromides DOI

Jyothis Dharaniyedath,

Vikash Kumar, Parthasarathy Gandeepan

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(40)

Published: June 18, 2024

Abstract Carbazole derivatives are vital in medicinal and materials chemistry, yet accessing diverse substitutions remains challenging. Here, we introduce a regioselective approach for C1 C8 alkynylation of carbazoles via palladium‐catalyzed C−H activation. This method provides direct route to mono‐ di‐alkynylated derivatives, addressing the scarcity alkynylated carbazole‐based materials. Our study broadens synthetic toolbox carbazole functionalization, offering potential applications optoelectronics, bio‐imaging, beyond, while contributing developing sustainable activation methodologies.

Language: Английский

Citations

1
Green light-mediated dual eosin Y/PdII-catalyzed C(sp2)–H arylation of N–H unprotected 2-arylquinazolinones DOI
Shuvam Mondal, Ranjan Jana

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(27), P. 5540 - 5545

Published: Jan. 1, 2024

An eosin Y/Pd II dual catalytic highly regio- and chemoselective C(sp 2 )–H monoarylation of N–H unprotected 2-phenyl quinazolinones with diazonium salts under visible light irradiation is disclosed.

Language: Английский

Citations

1