Enantioselective Fluorescence Recognition of Free α-Amino Acids by Ion-Type Ammonium Salt-Based Sensors DOI
L. Q. Bai, Chunyang Li, Dandan Wei

et al.

Journal of Fluorescence, Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 29, 2023

Language: Английский

Light-mediated catalytic enantioselective difluoroalkylation of β-ketoesters via phase-transfer catalysis DOI Creative Commons

Callum E. Adams,

Craig P. Johnston

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(13), P. 3639 - 3647

Published: Jan. 1, 2024

Asymmetric phase-transfer catalysis has been used to control the moderately enantioselective addition of difluoroalkyl radicals enolates β-ketoesters.

Language: Английский

Citations

2
Enantioselective Alkynylation of Pyrazole-4,5-diones with Terminal Alkynes Catalyzed by Copper/PyBisulidine DOI

Yu Chai,

Peng Chen,

Ruoran Wu

et al.

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(19), P. 13645 - 13654

Published: Sept. 8, 2023

A copper/PyBisulidine-catalyzed enantioselective alkynylation of electrophilic pyrazole-4,5-dione with terminal alkynes has been developed. Chiral tertiary propargylic alcohols bearing the pyrazolone motif were prepared yields (up to 99%) and enantioselectivities 99% ee). The prominent feature this protocol includes its mild reaction conditions good stereoselectivities. nonlinear effect study showed that catalytically active specie was a monomeric catalyst excess copper activated through π-system.

Language: Английский

Citations

4
A New 2-Aminospiropyrazolylammonium Cation with Possible Uses in the Topical Areas of Ionic Liquids DOI Creative Commons
L. A. Kаyukova, Анна В. Вологжанина

Molecules, Journal Year: 2024, Volume and Issue: 29(10), P. 2326 - 2326

Published: May 15, 2024

Based on the fact that 2-aminospiropyrazolinium compounds and structurally related azoniaspiro belong, in a broad sense, to class of ionic liquids, we have reviewed them studied their practical applications. To search for possible uses new compounds, it is necessary undertake comparison with based available information. The structures well-studied but little-studied rigid frameworks, limited conformational freedom, salt nature. These properties give ability organize nearby molecular space enable structure-forming synthesis zeolites, as well act phase-transfer catalysts selective biological effects. Additionally, these characteristics electrolytes serve materials anion exchange membranes fuel cells water electrolyzers. Thus, catalysts, structure-directing agents, electrolytes, power sources would encourage study similar which relation vitro antitubercular, antidiabetic, antimicrobial activities.

Language: Английский

Citations

1
Enantioselective α-Trifluoromethylthiolation of Carbonyl Compounds with AgSCF3 and Trichloroisocyanuric Acid DOI
Yakun Wang, Yingying Wang,

Wenwen Guo

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(11), P. 8011 - 8022

Published: May 28, 2024

We successfully developed an enantioselective trifluoromethylthiolation of structurally diverse carbonyl compounds. Trichloroisocyanuric acid and AgSCF

Language: Английский

Citations

1
Catalytic Enantioselective Propargylation of Pyrazolones by Amide-Based Phase-Transfer Catalysts DOI
Yakun Wang, Yingying Wang,

Xiaoyu Du

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(35), P. 7318 - 7323

Published: Aug. 26, 2024

In this paper, we developed a highly enantioselective alkylation of 4-substituted pyrazolones catalyzed by phase-transfer catalysis. Cheap halohydrocarbons were employed as electrophilic alkylationg agents, and propargyl, allyl, benzyl products with all-carbon quaternary stereocenters afforded excellent enantioselectivities good yields. We found that the unique structures catalyst (hydrogen bond donors C-9 hydroxyl group amide group, triphenyl at NH-position) important for enantioselectivity. Furthermore, chiral propargyl could be easily connected to azide molecules click cycloaddition, which offers opportunities obtain structurally diverse pyrazolones.

Language: Английский

Citations

1
Enantioselective trifluoromethylthiolation of 4-substituted pyrazolones catalyzed by amide-based phase transfer catalysts DOI
Yakun Wang,

Shuaifei Wang,

Yingying Wang

et al.

Molecular Catalysis, Journal Year: 2023, Volume and Issue: 547, P. 113323 - 113323

Published: June 21, 2023

Language: Английский

Citations

3
Enantioselective Fluorescence Recognition of Free α-Amino Acids by Ion-Type Ammonium Salt-Based Sensors DOI
L. Q. Bai, Chunyang Li, Dandan Wei

et al.

Journal of Fluorescence, Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 29, 2023

Language: Английский

Citations

1