Nitrogen-Based Organofluorine Functional Molecules: Synthesis and Applications

Chemical Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

Fluorine and nitrogen form a successful partnership in organic synthesis, medicinal chemistry, material sciences. Although fluorine-nitrogen chemistry has long rich history, this field received increasing interest made remarkable progress over the past two decades, driven by recent advancements transition metal organocatalysis photochemistry. This review, emphasizing contributions from 2015 to 2023, aims update state of art synthesis applications nitrogen-based organofluorine functional molecules chemistry. In dedicated sections, we first focus on fluorine-containing reagents organized according type groups attached nitrogen, including N-F, N-RF, N-SRF, N-ORF. review also covers nitrogen-linked building blocks, catalysts, pharmaceuticals, agrochemicals, underlining these components' broad applicability growing importance modern

Language: Английский

Recent Advances in Carbon-Centered Radical-Initiated Olefin Transformation Chemistry

Catalysts, Journal Year: 2025, Volume and Issue: 15(5), P. 461 - 461

Published: May 8, 2025

In recent years, carbon-centered radical-initiated olefin transformation reactions, including alkene Heck-type alkylation, hydroalkylation, and difunctionalization have attracted increasing attention been extensively developed. This review summarizes the advances in chemistry, such as radical-mediated reactions. area of research is divided into several sections based on types reactions divergent formation processes radicals. Drawing our group’s investigations, we show that efficient strategies gained significant traction synthetic chemistry due to their ability rapidly install functional groups enhance molecular complexity.

Language: Английский

Visible light-induced PPh₃/MI-promoted δ-C(sp³)–H chlorination and cyclization with N-chloro-arylsulfonamides via EDA complexes

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 3, 2024

PPh 3 , MI and N -chloro-arylsulfonamides could generate amidyl radicals via EDA complexes under visible light irradiation, these provide δ-chloro-arylsulfonamide -arylsulfonylpyrrolidine motifs in moderate yields 1,5-HAT process.

Language: Английский