RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(40), P. 27984 - 27996
Published: Jan. 1, 2023
A
green,
mild
and
eco-friendly
approach
for
the
three
component
one-pot
regioselective
synthesis
of
1,2,3-triazoles
from
thiiranes
has
been
introduced
in
presence
NiFe
Frontiers in Materials,
Journal Year:
2024,
Volume and Issue:
11
Published: July 31, 2024
In
this
study,
Co
3
O
4
nanoparticles
were
used
as
nanocatalyst
for
two
different
series
of
nitrogen-containing
heterocyclic
compounds,
including
pyrrole
(Pyo)
derivatives
and
pyrano
[2,
3-c]pyrazole
(Pya[2,
3-c]Pyz)
derivatives.
the
synthesis
derivatives,
using
15
mol%
10
catalyst
Pyo
Pya[2,
3-c]Pyz
respectively,
an
efficiency
between
83%
96%,
observed.
addition,
novel
Pya[2,3-c]Pyz
synthesized
their
structures
confirmed.
general,
advantages
cobalt
compared
to
previous
reports
include
new
lower
temperature
in
shorter
time
high
efficiency.
The
biological
properties
products,
such
antibacterial,
antifungal,
antioxidant
properties,
tested
investigated.
antibacterial
antifungal
tests,
IZD,
MIC,
MBC,
MFC
measured
reported.
activity,
IC
50
was
calculated
High
reusability,
green
environmentally
friendly,
products
with
higher
important
benefits
a
catalyst.
3-c]
Pyz
12.2
13.71
μg/mL,
16.18–17.75
respectively.
antimicrobial
testes,
MIC
2
4,096
2–2048
results
showed
that
property
more
than
but
effect
Pya[2,3-c]
proved
activity
does
not
depend
on
substitutions
is
close
each
other.
Therefore,
based
this,
proposed
mechanism
stability
DPPH
by
suggested.
Finally,
stable
resonance
its
justified.
has
rings
connected
together
pyrazole,
only
one
ring
(pyrrole).
So
can
be
attributed
having
bioactive
rings.
