Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 5, 2024
Abstract
Industrial
production
of
H
2
O
requires
lots
energy
and
causes
environmental
pollution.
Moreover,
in
subsequent
applications,
much
economic
loss
could
be
produced
during
the
transportation
process
its
dilution
process.
Therefore,
it
is
highly
desirable
for
situ
application
.
In
recent
years,
catalytic
synthesis
,
e.
g.,
direct
synthesis,
electrocatalytic
photocatalytic
has
attracted
more
attention
because
continuous
low‐concentration
by
can
directly
used
oxidation
organic
compounds,
effectively
avoiding
shortcomings
current
industrial
route.
Here,
we
briefly
reviewed
latest
processes
via
various
routes.
On
this
basis,
summarized
discussed
typical
conversion
reactions,
including
ammoximation
ketones,
alcohols,
C−H
bonds,
olefins.
Some
coupling
reactions
have
shown
excellent
performance
with
high
selectivity,
cost
been
significantly
reduced.
Finally,
utilization
were
analyzed,
some
strategies
promoting
efficiency
proposed.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(38)
Published: May 3, 2024
Chiral
secondary
alcohols,
serving
as
essential
structural
motifs,
hold
significant
potential
for
diverse
applications.
The
exploration
of
effective
synthetic
strategies
toward
these
compounds
is
both
attractive
and
challenging.
Herein,
we
present
an
asymmetric
oxa-Michael
reaction
involving
aliphatic
alcohols
nucleophiles
β-fluoroalkyl
vinylsulfones
catalyzed
by
bifunctional
phosphonium
salt
(BPS),
achieving
high
yields
excellent
enantioselectivities
(up
to
98
%
yield
ee).
Additionally,
a
sequential
process
including
debenzylation,
facilitated
BPS/Lewis
acid
cooperation,
was
revealed
synthesizing
chiral
alcohol
in
(81-88
%)
with
consistent
stereoselectivities.
Furthermore,
mechanistic
explorations
subsequent
results
unveiled
that
the
enantioselectivity
originates
from
hydrogen-bonding
ion-pair
interactions
between
BPS
catalyst
substrates.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 21, 2024
Abstract
Compounds
bearing
the
sulfoxide
moiety
display
an
important
class
of
molecules
in
pharmaceutical
industry.
Many
efforts
have
been
made
towards
development
novel,
sustainable,
easy‐to‐execute
and
industrially
friendly
processes.
A
novel
iodonium‐salt‐mediated
oxidation
protocol
for
conversion
sulfides
into
corresponding
sulfoxides
is
reported,
employing
DMSO
as
oxidant.
Several
decorated
with
various
functional
groups
were
tested,
leading
to
products
good
excellent
yields
remarkable
chemoselectivity.
The
was
successfully
applied
synthesis
active
ingredients
(APIs)
Sulforaphane
Modafinil.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(19), P. 5429 - 5436
Published: Jan. 1, 2024
A
metal-free,
visible-light-catalyzed
oxidative
cleavage
of
the
CC
bond
an
alkene
by
thiobenzoic
acid
in
water
under
O
2
atmosphere
has
been
developed.
ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(35), P. 37155 - 37162
Published: Aug. 22, 2024
This
study
introduces
a
novel
proline-catalyzed
oxidation
system
employing
hydrogen
peroxide
to
synthesize
quinones
from
diverse
range
of
substrates,
including
hydroquinones,
phenols,
resorcinols,
aldehydes,
and
polycyclic
aromatics.
approach
is
well-aligned
with
green
chemistry
principles,
offering
more
environmentally
benign
than
earlier
studies.
Notably,
this
uses
cost-effective
reagents,
proline
as
readily
available
organocatalyst,
reduced
equivalents
H
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(18), P. 9833 - 9839
Published: Jan. 1, 2024
Herein,
we
introduce
a
visible-light
promoted
green,
metal-free
method
for
the
regioselective
nucleophilic
ring
opening
of
epoxides
by
exploiting
arylazo
sulfones
as
PhotoAcid
Generators
(PAGs).
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(43), P. 31657 - 31662
Published: Jan. 1, 2024
The
anhydride–diacid
equilibrium
is
crucial
for
the
catalytic
cycle
of
maleic
anhydride
derivatives
in
N
-oxidation
pyridine
with
H
2
O
.
This
system
can
replace
stoichiometric
peracids,
such
as
m
-CPBA,
oxidants.
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 5, 2024
Abstract
Industrial
production
of
H
2
O
requires
lots
energy
and
causes
environmental
pollution.
Moreover,
in
subsequent
applications,
much
economic
loss
could
be
produced
during
the
transportation
process
its
dilution
process.
Therefore,
it
is
highly
desirable
for
situ
application
.
In
recent
years,
catalytic
synthesis
,
e.
g.,
direct
synthesis,
electrocatalytic
photocatalytic
has
attracted
more
attention
because
continuous
low‐concentration
by
can
directly
used
oxidation
organic
compounds,
effectively
avoiding
shortcomings
current
industrial
route.
Here,
we
briefly
reviewed
latest
processes
via
various
routes.
On
this
basis,
summarized
discussed
typical
conversion
reactions,
including
ammoximation
ketones,
alcohols,
C−H
bonds,
olefins.
Some
coupling
reactions
have
shown
excellent
performance
with
high
selectivity,
cost
been
significantly
reduced.
Finally,
utilization
were
analyzed,
some
strategies
promoting
efficiency
proposed.
