International Journal of Environmental & Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 20
Published: Dec. 5, 2024
A
novel
thiazole-based
heterocyclic
Schiff
base
(TSB)
was
designed
and
synthesised.
The
synthesised
structurally
characterised
by
using
fluorescence,
FT-IR
1H
NMR.
After
structural
characterisation,
the
sensing
properties
of
TSB
were
investigated
towards
different
metal
ions
such
as
Cr3+,
Hg2+,
Cu2+,
Cd2+,
Co2+,
Ni2+,
Zn2+,
Ag+,
Mg2+,
Ca2+,
Li+,
Na+,
K+.
significant
fluorescence
enhancement
observed
in
emission
at
584
nm
upon
interaction
with
Cu2+
compared
to
other
due
formation
TSB-Cu2+
complex.
2:1
binding
mode
between
confirmed
Job`s
plot
spectroscopy.
limit
detection
(LOD)
calculated
be
0.0051
ppm
(0.081
µM).
chemosensor
effectively
detected
various
environmental
samples,
demonstrating
high
recovery
rates
ranging
from
88.0
±
0.35%
107.0
0.47%.
antibacterial
activity
its
complex
also
evaluated
against
bacterial
strain.
results
showed
that
exhibited
good
activity,
highest
zone
inhibition
reaching
13.54
0.35
nm.
In
contrast,
consistently
demonstrated
improved
recorded
15.38
0.72
Applied Organometallic Chemistry,
Journal Year:
2025,
Volume and Issue:
39(5)
Published: April 9, 2025
ABSTRACT
The
detection
of
Fe(III)
ions
and
monitoring
pH
conditions
are
vital
for
safety,
efficiency,
sustainability
in
scientific
research,
environmental
management,
industrial
applications.
In
this
study,
two
1,2‐biphenyl‐substituted
benzimidazole‐1,2,3‐triazole
hybrids,
Pact
Oact,
were
designed,
developed,
characterized
by
various
spectroscopic
techniques
including
single‐crystal
XRD
analysis.
demonstrated
high
sensitivity
selectivity
towards
under
physiological
pH,
confirmed
through
visual
tests,
UV–visible,
fluorescence
spectroscopy,
with
limits
(LOD)
0.3
(emission)
0.07
nM
(absorption).
A
1:1
ligand‐to‐metal
binding
ratio
was
established
Job's
plot
supported
NMR,
mass,
VSM,
FT‐IR
analyses.
RGB
tool
(LOD:
3.4
mM)
a
paper
kit
test
its
portable
reversible
nature,
validated
EDTA
suggesting
potential
molecular
logic
gate
Environmental
highlighted
real
water
sample
analysis,
while
DFT
calculations
identified
favorable
metal
sites.
Additionally,
exhibited
highly
acidic
conditions,
containing
nitro
group,
showed
superior
vitro
anticancer
activity
against
HeLa
cells
compared
to
Pact,
higher
score
(−9.10
kcal/mol
vs.
−8.63
kcal/mol)
docking
studies
the
breast
cancer
estrogen
receptor
mutant
L536S
(PDB
ID:
6sbo).
Antioxidant
assays
further
Oact's
enhanced
radical
scavenging
potential.
Sensors & Diagnostics,
Journal Year:
2023,
Volume and Issue:
3(1), P. 64 - 78
Published: Nov. 15, 2023
5-Nitro-2-furaldehyde
based
Schiff
base
chemosensors,
N4R1–N4R3
with
varying
strengths
of
electron-withdrawing
groups
were
developed
for
the
discriminatory
sensing
arsenite
and
arsenate
ions
in
semi-aqueous
media.
Sensors & Diagnostics,
Journal Year:
2024,
Volume and Issue:
3(3), P. 431 - 439
Published: Jan. 1, 2024
Fluorescent
MQDs
were
synthesized
through
a
hydrothermal
process,
and
corresponding
test
paper
was
developed
for
the
visual
detection
of
an
anthrax
biomarker.
ChemistrySelect,
Journal Year:
2024,
Volume and Issue:
9(14)
Published: April 11, 2024
Abstract
A
mesogenic
glycine
based
Schiff
base
compound
of
the
type,
(E)‐methyl
2‐((2‐hydroxy‐4‐(tetradecyloxy)benzylidene)amino)acetate
(HL)
has
been
successfully
synthesized
and
characterized
using
analytical
spectroscopic
techniques.
The
was
evaluated
for
chemosensor
activity
towards
different
metal
ions
fluorescence
spectroscopy.
experiment
reveals
highly
efficient
selective
“turn‐on”
“turn‐off”
responses
intensity
zinc(II)
copper(II),
respectively,
in
presence
other
ions.
binding
constant
stoichiometry
ratio
were
determined
Benesi‐Hildebrand
equation
giving
1
:
stoichiometry.
limits
detection
both
estimated
from
titration
experiments.
reversibility
nature
probe
also
studied
EDTA
as
chelating
ligand.
compound,
HL
exhibits
two
INHIBIT
logic
gates
with
chemical
inputs
(i)
Zn
2+
(IN1)
Cu
(IN2)
(ii)
(IN2).
An
IMPLICATION
gate
obtained
when
serve
inputs.
found
to
exhibit
potent
antibacterial
interaction
BSA.
Molecular
docking
studies
carried
out
order
ascertain
degree
proteins.
New Journal of Chemistry,
Journal Year:
2023,
Volume and Issue:
47(45), P. 20785 - 20792
Published: Jan. 1, 2023
The
C
2
-symmetric
pseudopeptides
have
been
developed
as
a
state-of-the-art
soft
matter
for
recognition
and
supramolecular
self-assembly.
copper-guided
tuning
of
nano-assembly
is
promising
material
nano-architectonics
applications.
