Journal of Membrane Science, Journal Year: 2024, Volume and Issue: unknown, P. 123680 - 123680
Published: Dec. 1, 2024
Language: Английский
Cell Reports Physical Science, Journal Year: 2024, Volume and Issue: 5(7), P. 102053 - 102053
Published: June 17, 2024
Facing the problems encountered in contemporary hard and soft tissue repair, need for better solutions has never been so pressing. Traditional repair methods often fall short, leading to disappointing therapeutic outcomes complications. To address associated with engineering, polyurethane stands out because of its remarkable adaptability healing potential. This review embarks on a journey through essential properties diverse classifications polyurethane, unveiling modification strategies that amplify efficacy. Beyond process mending gaps, capability as sophisticated drug delivery system is explored offer glimpse into versatile applications. Most notably, cutting-edge advancements clinical trials bridging voids both are discussed. The present explores future bio-interface providing wave inventive poised redefine landscape regenerative medicine.
Language: Английский
Citations
5
Biomaterials Science, Journal Year: 2024, Volume and Issue: 12(17), P. 4471 - 4482
Published: Jan. 1, 2024
Hydrophilic antifouling coatings based on zwitterionic polymers have been widely applied for the surface modification of bone implants to combat biofilm formation and reduce likelihood implant-related infections. However, their long-term effectiveness is significantly limited by lack effective precise antibacterial activity. Here, a pH-responsive smart coating (PSB/GS coating) was designed robustly fabricated onto titanium-base using facile two-step method. First, dopamine (DA) poly(sulfobetaine methacrylate-
Language: Английский
Citations
4
Macromolecular Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown
Published: April 18, 2025
Abstract Polycarbonate thermoplastic polyurethanes (TPUs) have gained popularity for their excellent mechanical properties and relatively good environmental tolerance. However, traditional petroleum‐based TPUs are heavily dependent on non‐renewable resources difficult to balance anti‐water permeability with flexibility, severely limiting application in hostile situations. In this article, the newly designed synthesized CO 2 ‐derived oligomeric polycarbonate diol (PPCDL, a carbonate content >90%) polydimethylsiloxane (PDMS) as core materials. The influences of PDMS structures, well thermal, optical, mechanical, thoroughly investigated. results shown that strategy is successful improving performance both super high toughness simultaneously. introduction significantly improves (up 100.8 MJ m −3 ) elongation (at break>800%) materials while maintaining moderate tensile strength (15–28 MPa). More importantly, hydrophobic nature further enhances (water vapor transfer rate low 0.10 g −2 day −1 ). This work proposes novel developing eco‐friendly overall performances toughness, tunable strength, resilience, demonstrating potential wide applications requiring durability moisture resistance.
Language: Английский
Citations
0
Advanced Materials, Journal Year: 2025, Volume and Issue: unknown
Published: April 25, 2025
Abstract Shape memory polymers (SMPs) are deformable materials capable of recovering from a programmed temporary shape to permanent under specific stimuli. However, recovery SMPs is often accompanied by the evolution stiff soft state, leading significant decrease in strength/modulus and thereby impacting their practical applications. Although some attempts made pursue with self‐stiffening capability after recovery, modulus increase ratio much limited. Inspired recrystallization process CaCO 3 during crab molting, novel universal strategy developed construct water‐free using single thermal stimulus through harnessing polymer melting‐recrystallization. The achieved melting primary crystals, followed via at same temperature, which rate can be wide range. Additionally, conceptual applications these as artificial stents self‐enhancing supporting function successfully demonstrated. This work believed provide new insights for developing advanced devices.
Language: Английский
Citations
0
Bioactive Materials, Journal Year: 2024, Volume and Issue: 42, P. 366 - 378
Published: Sept. 9, 2024
Language: Английский
Citations
2
Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 12(1), P. 187 - 201
Published: Nov. 21, 2023
Schematic representation of the drug conjugated polyethyleneimine and its application in inhibiting bacterial biofilm formation on inanimate surfaces as well mouse skin abrasion model.
Language: Английский
Citations
6
Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 189, P. 545 - 558
Published: Sept. 1, 2024
Language: Английский
Citations
1
Postępy Mikrobiologii - Advancements of Microbiology, Journal Year: 2024, Volume and Issue: 63(4), P. 223 - 238
Published: Dec. 1, 2024
Abstract Polyurethanes (PUs) are exceptionally versatile polymers widely utilized in medicine due to their outstanding mechanical properties, biocompatibility, and adaptability various applications. This article explores advanced applications of polyurethane biomaterials medicine, the challenges posed by infections associated with use, innovative surface modification techniques improve functionality. PUs employed a diverse array medical devices, including non-implantable such as wound dressings, catheters, infusion sets; short-term implants like bone stabilizers tracheostomy tubes; long-term tissue regeneration scaffolds, artificial blood vessels, heart valves. Despite many advantages, use carries significant risk infections, ventilator-associated pneumonia, infective endocarditis, urinary tract infections. An important challenge lies bacterial biofilms, which complicate treatment enhance resistance antibiotics. To address these issues, PU methods being developed, laser texturing, nanoparticle deposition antibacterial ion implantation, cold metal spraying, integration biodegradable biocompatible components, plasma modifications. These aim biomaterials’ properties thereby reducing infection risks improving clinical outcomes. underscores importance ongoing research effectively combat biomaterial-associated broaden polyurethanes. The development holds great promise for patient quality life efficacy treatments.
Language: Английский
Citations
1
Molecules, Journal Year: 2023, Volume and Issue: 28(24), P. 8040 - 8040
Published: Dec. 11, 2023
Zwitterionic polymer coatings facilitate the formation of hydration layers via electrostatic interactions on their surfaces and have demonstrated efficacy in preventing biofouling. They emerged as a promising class marine antifouling materials. However, designing multifunctional, environmentally friendly, natural products-derived zwitterionic that simultaneously resist biofouling, inhibit protein adhesion, exhibit strong antibacterial properties, reduce algal adhesion is significant challenge. This study employed two diisocyanates crosslinkers urushiol ethanolamine raw The coupling reaction with hydroxyl groups was to synthesize urushiol-based precursors. Subsequently, sulfobetaine moieties were introduced into precursors, developing friendly high-performance zwitterionic-functionalized polyurushiol coatings, denoted HUDM-SB IPUDM-SB. sulfobetaine-functionalized coating exhibited significantly enhanced hydrophilicity, static water contact angle reduced less than 60°, excellent resistance adhesion. IPUDM-SB up 99.9% against common Gram-negative bacteria (E. coli V. alginolyticus) Gram-positive (S. aureus Bacillus. sp.). achieved exceeding 95.0% four bacterial species. Furthermore, effectively inhibited growth reproduction cells by microalgae does not contain agents, making it green, biomaterial-based solution for antifouling.
Language: Английский
Citations
3
Progress in Organic Coatings, Journal Year: 2024, Volume and Issue: 191, P. 108421 - 108421
Published: March 30, 2024
Language: Английский
Citations
0