Zinc oxide nanoparticles: Pathways to micropollutant adsorption, dye removal, and antibacterial actions - A study of mechanisms, challenges, and future prospects

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: 1312, P. 138545 - 138545

Published: May 6, 2024

Language: Английский

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Comprehensive insights into mechanism of nanotoxicity, assessment methods and regulatory challenges of nanomedicines

Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)

Published: Oct. 4, 2024

Nanomedicine has the potential to transform healthcare by offering targeted therapies, precise diagnostics, and enhanced drug delivery systems. The National Institutes of Health coined term "nanomedicine" describe use nanotechnology in biological system monitoring, control, diagnosis, treatment. continues receive increasing interest for rationalized therapeutics pharmaceutical agents achieve required response while reducing its side effects. However, as advance, concerns about toxicological effects have also grown. This review explores current state nanomedicine, focusing on types nanoparticles used their associated properties that contribute nanotoxicity. It examines mechanisms through which exert toxicity, encompassing various cellular molecular interactions. Furthermore, it discusses assessment methods employed evaluate nanotoxicity, in-vitro in-vivo models, well emerging techniques. addresses regulatory issues surrounding nanotoxicology, highlighting challenges developing standardized guidelines ensuring secure translation nanomedicine into clinical settings. ethical with understanding safety profile is essential effective therapeutic applications.

Language: Английский

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Cerium Oxide Nanoparticles and Their Polymeric Composites: Advancements in Biomedical Applications

Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2024, Volume and Issue: unknown

Published: July 27, 2024

Language: Английский

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Phytonanoparticles as novel drug carriers for enhanced osteogenesis and osseointegration

Discover Nano, Journal Year: 2025, Volume and Issue: 20(1)

Published: Jan. 16, 2025

Abstract Phytonanoparticles have emerged as a promising class of biomaterials for enhancing bone regeneration and osseointegration, offering unique advantages in biocompatibility, multifunctionality, sustainability. This comprehensive review explores the synthesis, characterization, applications phytonanoparticles tissue engineering. The green synthesis approach, utilizing plant extracts reducing stabilizing agents, yields nanoparticles with intrinsic bioactive properties that can synergistically promote osteogenesis. We examine mechanisms by which phytonanoparticles, particularly those derived from gold, silver, zinc oxide, influence key molecular pathways osteogenesis, including RUNX2 Osterix signaling. discusses advanced strategies phyto-nanoparticle design, such surface functionalization stimuli-responsive release mechanisms, enhance their efficacy applications. Preclinical studies demonstrating improved osteoblast proliferation, differentiation, mineralization are critically analyzed, along emerging clinical data. Despite results, scalability, standardization, regulatory approval challenges persist. also addresses economic environmental implications production. Looking ahead, we identify research directions, developing personalized therapies, combination approaches stem cells or gene delivery, long-term safety assessments. By harnessing power plant-derived nanomaterials, represent an innovative approach to addressing complex regeneration, potential spanning dental, orthopedic, maxillofacial surgery. Graphical abstract

Language: Английский

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Development and Evaluation of SA/PVP/γ-Al₂O₃ Nanocarriers for Targeted Delivery of Curcumin in Colon Cancer Therapy

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106632 - 106632

Published: Jan. 1, 2025

Language: Английский

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New strategies for lung cancer diagnosis and treatment: applications and advances in nanotechnology

Biomarker Research, Journal Year: 2024, Volume and Issue: 12(1)

Published: Nov. 13, 2024

Lung cancer leads in causing cancer-related mortality worldwide, continually posing a significant threat to human health. Current imaging diagnostic techniques, while offering non-invasive detection, suffer from issues such as insufficient sensitivity and the risks associated with radiation exposure. Pathological diagnosis, gold standard for confirmation, also faces challenges like invasiveness high costs. In treatment, surgery, radiotherapy, chemotherapy are main modalities, each encountering related precision, environmental adaptability, side effects. Nanotechnology's advancement provides new solutions diagnosis treatment of lung cancer, promising enhance accuracy reduce effects during treatment. This article introduces types nanomaterials used field comprehensive overview current research on application nanotechnology early screening, monitoring summarizing ongoing clinical findings.

Language: Английский

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Scheelite-Type Cerium Vanadate Nanoparticles as Functional Electrode Material for Hematotoxicity Chloromycetin Detection

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(15), P. 17295 - 17304

Published: July 15, 2024

In this work, we report the synthesis of cerium vanadate (CeVO4) nanoparticles and their application in modifying screen-printed carbon electrodes (SPCEs) for electrochemical detection chloramphenicol (CPC). The physicochemical properties CeVO4 were thoroughly investigated by using X-ray diffraction (XRD), Raman spectroscopy, photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), confirming crystallinity nanostructure. Electrochemical assays demonstrated that CeVO4-modified SPCE exhibited significantly enhanced electrocatalytic performance toward CPC, as evidenced increased peak currents decreased charge-transfer resistance. A series experiments involving cyclic voltammetry differential pulse established a diffusion-controlled mechanism CPC redox reactions on modified electrode surface. sensor showed wide linear range (0.01–550 μM) limit (0.002 was lower than bare SPCE. Furthermore, displayed excellent selectivity presence potential interfering substances, remarkable stability over repeated cycling, consistent reproducibility, highlighting robustness CeVO4/SPCE sensing platform. integration into SPCEs presents significant advancement development sensitive sensors with implications environmental monitoring, food safety assessment, clinical diagnostics.

Language: Английский

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Recent advancements in nanoparticles for cancer treatment

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(3)

Published: Feb. 10, 2025

Language: Английский

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Amphotericin B Delivery Systems: Current Advances and Potential Directions in Oral Candidiasis Treatment

Precision medicine and engineering., Journal Year: 2025, Volume and Issue: unknown, P. 100021 - 100021

Published: Feb. 1, 2025

Language: Английский

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High-Pressure Single-Crystal X-Ray Diffraction Study of ErVO₄

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 28, 2025

We present an investigation into the crystal structure of ErVO4 under variable pressure conditions. The high-pressure single-crystal X-ray diffraction experiments performed employing helium as medium facilitated refinements up to 24.1(2) GPa. transition from zircon scheelite was observed at a 7.9(1) In contrast previous reports, we did not detect any sign phase coexistence. also observe second transitions previously predicted by density-functional theory occur below 20 determination dependence unit-cell parameters and volume yields precise values for linear compressibility each axis pressure-volume equation state both phases. Additional information on mechanical properties ErVO4, obtained calculations, is reported.

Language: Английский

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