Enhanced Biodegradability, Osteogenesis, and Angiogenesis of Zn-Li Alloys through Calcium Plasma Immersion Ion Implantation

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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Overview of biodegradable materials for bone repair and osteosarcoma treatment: From bulk to scaffolds

Biomaterials Advances, Journal Year: 2025, Volume and Issue: unknown, P. 214317 - 214317

Published: April 1, 2025

Language: Английский

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Microstructure, Mechanical Properties, and Corrosion Behavior of Zn-x wt.% Ti (x = 0, 0.3 and 1) Alloys for Biomedical Applications

Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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MOFs-based nanomaterials for bone repair and regeneration: Current status and future perspectives

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 111211 - 111211

Published: April 1, 2025

Language: Английский

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Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: April 25, 2025

Abstract The potential applications of rare earth elements (REEs) in biomedical fields have been intensively investigated. Numerous studies shown that doping biomaterials with REEs can enhance their properties. Gadolinium (Gd) is a biocompatible REE holds promise applications. This review examines the use Gd‐doped osteogenic, antimicrobial, anticancer applications, and bioimaging bioprobes, as reported literature until December 2024. included demonstrate Gd‐containing promote osteogenesis, antimicrobial properties, perform well bioimaging. Taken together, they point to considerable thus avenues for future research.

Language: Английский

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Biological Properties of Magnesium Alloys and Alloying Elements Suitable for the Development of Biodegradable Implants for Osteosynthesis (Literature Review)

TERRA ORTHOPAEDICA, Journal Year: 2025, Volume and Issue: 1(124), P. 44 - 51

Published: April 30, 2025

Background. In recent years, countries such as Japan, China, the United States, and others have been actively searching for bioresorbable materials osteosynthesis that do not require removal. According to preliminary data, biodegradable fixators possess osteoinductive osteoproliferative properties, positively influencing bone healing at fracture site. Currently, involves use of implants made steel titanium alloys. The main disadvantage is need a secondary surgical procedure remove them, which extends patient’s disability period. Objective. This study aims analyze summarize scientific research on effects metal ions tissue regeneration, vascularization, surrounding tissues when using fractures current stage. Materials Methods. Based data from scientometric databases Scopus Web Science, systematic approach, along with bibliosemantic analytical methods, was applied. Results Discussion. Modern engineering gradually shifting bioinert development implementation capable stimulating regeneration. It has established play key role in biological processes human body. particular, zinc (Zn), boron (B), zirconium (Zr) significant potential regeneration tissue. They contribute biochemical reactions involved metabolism, enhance regenerative processes, influence activity osteoblasts, osteoclasts, immune system cells, endothelial fibroblasts. degradation products magnesium (Mg)-based an important shaping microenvironment, participating complex interactions between cells. contributes effective

Language: Английский

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Biodegradable Zn-Li-Mn alloy to achieve optimal strength and ductility for bone implants

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: May 1, 2025

Language: Английский

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Machine learning-based optimization of cytotoxicity testing for assessing Zn-based biodegradable metals

Materials Today Bio, Journal Year: 2025, Volume and Issue: unknown, P. 101816 - 101816

Published: May 1, 2025

Language: Английский

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Mg-based implants with a sandwiched composite coating simultaneously facilitate antibacterial and osteogenic properties

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: 12(8), P. 2015 - 2027

Published: Jan. 1, 2024

Mg-based implants with a sandwiched coating simultaneously facilitate antibacterial and osteogenic properties due to the synergistic biological effects of TCS Mg 2+ .

Language: Английский

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Zinc-energized dynamic hydrogel accelerates bone regeneration via potentiating the coupling of angiogenesis and osteogenesis

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: April 3, 2024

Insufficient initial vascularization plays a pivotal role in the ineffectiveness of bone biomaterials for treating defects. Consequently, enhancing angiogenic properties repair holds immense importance augmenting efficacy regeneration. In this context, we have successfully engineered composite hydrogel capable promoting process To achieve this, researchers first prepared an aminated bioactive glass containing zinc ions (AZnBg), and hyaluronic acid contains aldehyde groups (HA-CHO). The was formed by combining AZnBg with gelatin methacryloyl (GelMA) HA-CHO through Schiff base bonding. This has good biocompatibility. addition, exhibited significant osteoinductive activity, activity ALP, formation calcium nodules, expression osteogenic genes. Notably, also promoted umbilical vein endothelial cell migration as well tube releasing ions. results vivo study demonstrated that implantation defect distal femur rats could effectively stimulate generation development new blood vessels, thus accelerating healing process. conclusion, zinc-containing hydrogels can promote growth angiogenesis, making it viable option critical-sized

Language: Английский

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