Impact of Magneto‐Mechanical Actuation on Cell Differentiation: A Study Using Wireless, 3D‐Printed Device and a Porous Ferrogel

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Abstract Cells perceive external and internally generated forces of different kinds, significantly impacting their cellular biology. In the relatively nascent field mechanobiology, impact such is studied further utilized to broaden knowledge developmental pathways, disease progression, tissue engineering, developing novel regenerative strategies. However, extensive considerations mechanotransduction pathways for biomedical applications are still broadly limited due a lack affordable technologies in terms devices simple magnetic actuatable materials. Herein, synthesizing monophasic, macroporous, situ‐fabricated gelatin‐based ferrogel reported using polyethylene glycol (PEG) coated‐iron oxide (magnetite) particles with high magnetization. Developing 3D printed, compact, wireless device capable providing wide range magneto‐mechanical actuation susceptible materials noncontact manner reported. Using ferrogel, C2C12 myoblast differentiation under actuation, significant differences myogenin, marker, expression behavior observed. Due careful design considerations, robust component selection, easy availability low‐cost precursor responsive material fabrication, device‐ferrogel combination can be easily adapted routine biological studies, thereby helping mechanobiology exciting new

Language: Английский

A comprehensive review on quantification of various biomarkers for the detection of oral carcinoma via electrochemical biosensors

Microchemical Journal, Journal Year: 2024, Volume and Issue: 207, P. 111741 - 111741

Published: Sept. 23, 2024

Language: Английский