The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 16, 2024
An
Earth-abundant
Mn-PNP
pincer
complex-catalyzed
terpenylation
of
cyclic
and
acyclic
ketones
secondary
alcohol
1-phenylethanol
using
isoprenoid
derivatives
prenol,
nerol,
phytol,
solanesol,
E-farnesol
as
allyl
surrogates
is
reported.
The
C-C
coupling
reactions
are
green
atom-economic,
proceeding
via
dehydrogenation
alcohols
following
a
hydrogen
autotransfer
methodology
aided
by
metal-ligand
cooperation.
ACS Catalysis,
Journal Year:
2024,
Volume and Issue:
14(17), P. 13451 - 13496
Published: Aug. 26, 2024
Alcohols
are
abundant
with
versatile
structural
variety
and
have
ample
use
as
pivotal
functional
groups
in
numerous
organic
processes.
Because
of
their
frequent
occurrence
enumerable
natural
products,
bioactive
molecules,
medicinal
components,
alcohol
functionalities
provide
a
promising
scope
research
to
advance
the
operational
diversity
for
improving
clinical
success.
Recent
years
witnessed
design
modern
C–C
C–heteroatom
bond-forming
approaches
easily
accessible
commercially
available
unactivated
aliphatic
alcohols
native
adaptive
sp3
handles,
hence
offering
groundbreaking
transformative
pathways
functionalization
complex
molecular
architectures.
The
judicial
application
appropriate
activating
generate
alkyl
radical
from
through
C–O
bond
fragmentation
employ
it
potential
alkylating
agent
unfolds
unique
synthetic
strategies,
thereby
replacing
obvious
requirement
halides.
This
review
elaborately
discusses
recent
trends
regarding
using
C(sp3)-centered
various
chemical
transformations
by
exploiting
different
activation
modes
disrupter
under
photoredox
catalysis.
presentation
is
organized
nature
scaffolds,
kind
formation,
progress
achieved
this
domain
since
original
discovery
providing
illustrative
examples
mechanistic
details,
focus
on
difficulties
future
prospects.
ChemistrySelect,
Journal Year:
2024,
Volume and Issue:
9(32)
Published: Aug. 22, 2024
Abstract
Cross‐coupling
of
nitriles
and
alcohols
offers
an
environmentally
friendly
atom‐economical
method
for
the
synthesis
various
valuable
compounds.
These
compounds
include
α
‐alkylated
‐olefinated
nitriles,
primary
amines,
imines,
N
‐alkylation
amides,
‐heterocycles,
δ
‐hydroxynitriles,
olefins,
etc
.
Herein,
we
have
reviewed
recent
developments
(from
2013–date)
transition‐metal‐catalyzed
cross‐coupling
alcohols.
A
number
transition
metal
complexes
such
as
noble
metals
Ru
Ir,
well
base
Mn,
Fe,
Co,
Ni
are
presented.
Moreover,
different
product
types,
reaction
conditions
mechanisms
discussed
to
understand
catalyst
development.
ACS Omega,
Journal Year:
2025,
Volume and Issue:
10(9), P. 9649 - 9660
Published: Feb. 24, 2025
Construction
of
a
C-C
bond
via
alkylation
ketones
with
alcohol
as
the
alkylating
source
by
employing
hydrogen-borrowing
strategy
is
attracting
significant
attention
and
highly
appealing
due
to
its
simplicity,
cost-effectiveness,
environmental
benefits,
fact
that
water
only
byproduct.
The
development
heterogeneous
catalysts
based
on
nonprecious
base
metals
progressing
rapidly.
Our
newly
disclosed
manganese-doped
cerium
oxide
nanocomposite
(10
wt
%
Mn@CeO2)
stands
out
cost-efficient
air-stable
catalyst,
synthesized
through
straightforward
coprecipitation
method
employed
for
α-alkylation
primary
alcohols
strategy.
X-ray
diffraction
(XRD)
analysis
confirms
high
crystallinity
CeO2,
while
field
emission
scanning
electron
microscopy
(FE-SEM)
high-resolution
transmission
(HR-TEM)
images
reveal
MnO2
nanoparticles,
measuring
19
nm
in
size,
uniformly
decorated
rod-shaped
CeO2
which
have
size
33
nm.
photoelectron
spectroscopy
(XPS)
uncovers
presence
Mn4+
species
embedded
nanorods.
Electron
paramagnetic
resonance
(EPR)
further
indicates
surface
defects
contribute
impressive
catalytic
yield,
ranges
from
70
98%
α-alkylated
ketones.
Thermogravimetric
(TGA)
demonstrates
remarkable
thermal
stability
maintaining
up
800
°C.
Additionally,
inductively
coupled
plasma
mass
spectrometry
(ICP-MS)
no
leaching
Mn
ions,
emphasizing
heterogeneity
catalyst.
Remarkably,
10
Mn@CeO2
recycled
six
cycles
loss
activity.
This
study
underscores
synergistic
effect
between
metal
redox
pair
key
exceptional
activity
reactions,
making
promising
catalyst
sustainable
efficient
formation.
Asian Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
13(8)
Published: May 10, 2024
Abstract
Herein,
we
report
an
efficient
and
sustainable
manganese‐catalyzed
α‐C−H
bond
alkylation
methodology
to
synthesize
branched
sulfones
via
a
hydrogen
borrowing
pathway.
The
air‐stable
phosphine‐free
Mn‐catalyst,
(NNN)Mn(II)Cl
2
was
synthesized
by
using
earth‐abundant,
commercially
available,
inexpensive
precursor
MnCl
.4H
O,
stable
NNN
pincer
i.
e.
[N‐((benzimidazole‐2‐yl)methyl)quinoline‐8‐amine]
ligand
system.
Taking
benzyl
phenyl
as
substrates,
alcohol
derivatives
alkylating
agents,
range
of
were
in
40–82
%
isolated
yields
complex
the
catalyst
under
open‐air
conditions.
Control
experiments
deuterium
incorporation
studies
have
also
been
conducted
investigate
possible
reaction
mechanism
provide
evidence
for
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(46)
Published: June 12, 2024
The
synthesis
of
sulfoxide-functionalized
NHC
ligand
precursors
were
carried
out
by
direct
and
mild
oxidation
from
corresponding
thioether
with
high
selectivity.
Using
these
salts,
a
series
cationic
[Ru(II)(η
Inorganic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 26, 2024
The
search
for
an
iron
analog
of
the
established
ruthenium-based
catalysts
containing
methylene-extended
4,5-bis(diorganophosphinomethyl)acridine
ligands,
[FeHCl(CO)(L
