Double-Bridging Increases the Stability of Zinc(II) Metal–Organic Cages
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(45), P. 30958 - 30965
Published: Nov. 4, 2024
A
key
feature
of
coordination
cages
is
the
dynamic
nature
their
coordinative
bonds,
which
facilitates
synthesis
complex
polyhedral
structures
and
post-assembly
modification.
However,
this
can
limit
cage
stability.
Increasing
robustness
important
for
real-world
use
cases.
Here
we
introduce
a
double-bridging
strategy
to
increase
stability,
where
designed
pairs
bifunctional
subcomponents
combine
generate
rectangular
tetratopic
ligands
within
pseudo-cubic
Zn8L6
cages.
These
withstand
transmetalation,
addition
competing
ligands,
nucleophilic
imines,
under
conditions
single-bridged
congeners
decompose.
Our
approach
not
only
increases
stability
while
maintaining
structure,
but
also
enables
incorporation
additional
functional
units
in
proximity
cavity.
The
larger
cages,
are
inaccessible
as
congeners.
Language: Английский
Synthesis of a Pd2L4 Hydrazone Molecular Cage Through Multiple Reaction Pathways
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(22), P. 11861 - 11861
Published: Nov. 5, 2024
Molecular
cages
are
preorganized
molecules
with
a
central
cavity,
typically
formed
through
the
reaction
of
their
building
blocks
chemical
bonds.
This
requires,
in
most
cases,
forming
and
breaking
reversible
bonds
during
cage
formation
pathway
for
error
correction
to
drive
product.
In
this
work,
we
focus
on
both
Pd-ligand
hydrazone
implemented
structure
Pd
Language: Английский