Application of nanoscale metal-organic coordination polymers in cancer therapy
Chemical Engineering Journal,
Journal Year:
2024,
Volume and Issue:
496, P. 154342 - 154342
Published: July 27, 2024
Language: Английский
Beyond chemotherapy: Spatiotemporal activation of metal complexes for deep-tissues precision medicine
Yida Pang,
No information about this author
Fang Zhao,
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Yuting Wang
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et al.
Coordination Chemistry Reviews,
Journal Year:
2025,
Volume and Issue:
535, P. 216664 - 216664
Published: March 30, 2025
Language: Английский
Nanosensitizer-assisted sonodynamic therapy for breast cancer
Jing Yu,
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Jun-Rui Hu,
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Yi Tian
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et al.
Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: April 7, 2025
Abstract
Breast
cancer
is
the
most
commonly
diagnosed
worldwide.
Despite
advancements
in
therapeutic
modalities,
its
prognosis
remains
poor
owing
to
complex
clinical,
pathological,
and
molecular
characteristics.
Sonodynamic
therapy
(SDT)
a
promising
approach
for
tumor
elimination,
using
sonosensitizers
that
preferentially
accumulate
tissues
are
activated
by
low-intensity
ultrasound
produce
reactive
oxygen
species.
However,
clinical
translation
of
SDT
faces
challenges,
including
limited
efficiency
resistance
posed
microenvironment.
The
emergence
nanomedicine
offers
innovative
strategies
address
these
obstacles.
This
review
discusses
enhancing
efficacy
sonosensitizers,
rational
structural
modifications,
improved
tumor-targeted
enrichment,
microenvironment
remodeling,
imaging-guided
therapy.
Additionally,
SDT-based
multimodal
therapies,
such
as
sono-chemotherapy,
sono-immunotherapy,
sono-photodynamic
therapy,
their
potential
applications
breast
treatment
summarized.
underlying
mechanisms
briefly
outlined.
Finally,
this
highlights
current
challenges
prospects
SDT,
providing
insights
into
future
may
improve
outcomes
cancer.
Graphical
abstract
Language: Английский
Recent Development of Organic Afterglow Probes for Diagnosis and Treatment of Cancer
Meiqin Li,
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Le Tu,
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Huiling Wang
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et al.
Targets,
Journal Year:
2024,
Volume and Issue:
2(4), P. 327 - 340
Published: Oct. 31, 2024
Afterglow
imaging
plays
a
crucial
role
in
the
cancer
treatment
field.
In
contrast
to
inorganic
afterglow
agents,
organic
agents
possess
easily
modifiable
structures
and
exhibit
excellent
biocompatibility,
thereby
presenting
significant
prospects
for
application
tumor
diagnosis
management.
this
review,
we
summarize
design
principles
applications
of
probes
therapy.
Finally,
discuss
future
challenges
Language: Английский