The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(24), P. 18698 - 18706
Published: Dec. 10, 2024
A highly stereoselective protocol for the (3 + 2)-annulation of biphenyl-bridged seven-membered cyclic
Language: Английский
The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(24), P. 18698 - 18706
Published: Dec. 10, 2024
A highly stereoselective protocol for the (3 + 2)-annulation of biphenyl-bridged seven-membered cyclic
Language: Английский
Organic Letters, Journal Year: 2025, Volume and Issue: unknown
Published: March 25, 2025
A highly efficient enantioselective Michael addition of cyclic N-sulfonylimines with nitroalkenes has been developed, utilizing a bifunctional squaramide catalyst. This approach achieves remarkable results, delivering products high yields and outstanding stereoselectivities, reaching up to 97% yield, >20:1 dr, >99% ee. Furthermore, an asymmetric tandem reaction 2-nitroallylic acetates established. innovative methodology involves Michael/intramolecular aza-Michael cascade, leading the formation enantioenriched benzosultam-fused tricyclic compounds excellent stereoselectivities (up dr ee).
Language: Английский
Citations
0Published: Jan. 1, 2025
Language: Английский
Citations
0Tetrahedron Letters, Journal Year: 2025, Volume and Issue: unknown, P. 155624 - 155624
Published: May 1, 2025
Language: Английский
Citations
0Molbank, Journal Year: 2024, Volume and Issue: 2024(4), P. M1931 - M1931
Published: Dec. 5, 2024
A highly efficient method has been developed for preparing 2-((3R,9bS)-5,5-dioxido-2,3-dihydro-9bH-benzo[4,5]isothiazolo[3,2-b]oxazol-3-yl)-1-phenylethan-1-one. This enantioenriched title compound was obtained via an organocatalytic asymmetric [3+2]-cycloaddition of benzo[d]isothiazole 1,1-dioxide with (E)-4-hydroxy-1-phenylbut-2-en-1-one, using a bifunctional squaramide-based chiral catalyst. The reaction yielded 99% the product high enantioselectivity and diastereoselectivity (89:11 er >20:1 dr). structure newly synthesized confirmed by 1H-, 13C-NMR, IR mass spectral data.
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(24), P. 18698 - 18706
Published: Dec. 10, 2024
A highly stereoselective protocol for the (3 + 2)-annulation of biphenyl-bridged seven-membered cyclic
Language: Английский
Citations
0