Synergistic cancer treatment using porphyrin-based metal-organic Frameworks for photodynamic and photothermal therapy DOI
Mahsa Akbari Oryani, Mojtaba Tarin,

Leila Rahnama Araghi

et al.

Journal of drug targeting, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: Dec. 2, 2024

Recent advancements in multifunctional nanomaterials for cancer therapy have highlighted porphyrin-based metal-organic frameworks (MOFs) as promising candidates due to their unique properties and versatile applications. This overview focuses on the use of MOFs combined photodynamic (PDT) photothermal (PTT) treatment. Porphyrin-based offer high porosity, tuneable structures, excellent stability, making them ideal drug delivery therapeutic The incorporation porphyrin molecules into MOF framework enhances light absorption energy transfer, leading improved effects. Additionally, porosity allows encapsulation agents, further enhancing efficacy. In PDT, generate reactive oxygen species (ROS) upon activation, destroying cells. enable conversion heat, resulting localised hyperthermia tumour ablation. combination PDT PTT a single platform offers synergistic effects, better outcomes, reduced side selectivity. dual-modal treatment strategy provides precise spatiotemporal control over process, paving way next-generation therapeutics with enhanced efficacy Further research optimisation are needed clinical

Language: Английский

Unveiling Cutting-edge progress in coordination chemistry of the Metal-Organic frameworks (MOFs) and their Composites: Fundamentals, synthesis Strategies, electrochemical and environmental applications DOI
Valentine Chikaodili Anadebe, Abhinay Thakur, Chandrabhan Verma

et al.

Journal of Industrial and Engineering Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Zirconium-based metal–organic frameworks for electrochemical energy storage DOI

Chung-Huan Wu,

Kuan-Chu Wu,

Cheng‐Hui Shen

et al.

Coordination Chemistry Reviews, Journal Year: 2025, Volume and Issue: 538, P. 216704 - 216704

Published: April 19, 2025

Language: Английский

Citations

0
“Rust to Riches”: Harnessing iron-oxide-Zr MOF hybrid composite for enhanced oxygen evolution reaction under low pH DOI Creative Commons

Sobhna Acharya,

Harshita Bagdwal,

Ritu Ladhi

et al.

APL Materials, Journal Year: 2025, Volume and Issue: 13(5)

Published: May 1, 2025

Energy consumption has become a critical global challenge, demanding innovative and sustainable solutions. Consequently, there is an increasing demand for efficient durable electrocatalyst synthesis that can replace expensive noble metal-based catalysts water-splitting reactions. In this context, we have successfully synthesized composite material combining Zr-based metal–organic framework (MOF), UIO-66-NH2, with Fe2O3 derived from rust—a discarded waste material. The synergistic interaction between MOF enhances the catalytic performance by effectively structural advantages of active sites provided Fe2O3. results indicated was overpotential 209 mV at 10 mA/cm2 compared to pristine MOF. Moreover, demonstrated long-term durability more than 9 h under harsh acidic conditions, outperforming many conventional in terms stability, efficiency, cost-effectiveness. By transforming materials into high-performance composites, work presents approach addressing energy crisis, offering cost-effective environmentally friendly solution meet growing demands.

Language: Английский

Citations

0
Electrochemical hydrogenation and hydrogenolysis of furfural on copper electrode enhanced by surface environment modulation with metal–organic framework DOI

Yu-Shuo Lee,

Chi-Wei Huang,

Chun-Ting Yueh

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159800 - 159800

Published: Jan. 1, 2025

Language: Английский

Citations

0
Synergistic cancer treatment using porphyrin-based metal-organic Frameworks for photodynamic and photothermal therapy DOI
Mahsa Akbari Oryani, Mojtaba Tarin,

Leila Rahnama Araghi

et al.

Journal of drug targeting, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: Dec. 2, 2024

Recent advancements in multifunctional nanomaterials for cancer therapy have highlighted porphyrin-based metal-organic frameworks (MOFs) as promising candidates due to their unique properties and versatile applications. This overview focuses on the use of MOFs combined photodynamic (PDT) photothermal (PTT) treatment. Porphyrin-based offer high porosity, tuneable structures, excellent stability, making them ideal drug delivery therapeutic The incorporation porphyrin molecules into MOF framework enhances light absorption energy transfer, leading improved effects. Additionally, porosity allows encapsulation agents, further enhancing efficacy. In PDT, generate reactive oxygen species (ROS) upon activation, destroying cells. enable conversion heat, resulting localised hyperthermia tumour ablation. combination PDT PTT a single platform offers synergistic effects, better outcomes, reduced side selectivity. dual-modal treatment strategy provides precise spatiotemporal control over process, paving way next-generation therapeutics with enhanced efficacy Further research optimisation are needed clinical

Language: Английский

Citations

2