Luminescence “on-off-on” sensing of acute myocardial infarction biomarker miRNA-208a based on copper nanoclusters-MoS 2 FRET system DOI Creative Commons
Suzhen Zhang,

Danling Mei,

Hongming Fang

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

Abstract MiRNA-208a is a molecular marker for the early stage of acute myocardial infarction (AMI), with satisfactory specificity and relatively short time window, making it highly suitable diagnosis AMI. In this study, we designed CuNCs-cDNA-MoS2 fluorescent probe established fluorescence resonance energy transfer (FRET) enzyme-free biosensor "on-off-on" detection miRNA-208a. The results showed that limit miRNA-208a was 900 pM, linear range 1 to 10 nM. Interestingly, after addition RNase inhibitor, serum were reduced 5 minutes 380 respectively. It also has wide (1–20 nM), recovery rate 98.13 101.20%. Compared traditional methods, strategy simple, rapid, sensitive, cost-effective. summary, FRET-based sensor provides high-performance method detecting

Language: Английский

Luminescent Hydride-Free [Cu7(SC5H9)7(PPh3)3] Nanocluster: Facilitating Highly Selective C–C Bond Formation DOI
Sourav Biswas, Amit Kumar Pal, Milan Kumar Jena

et al.

Journal of the American Chemical Society, Journal Year: 2024, Volume and Issue: 146(30), P. 20937 - 20944

Published: July 9, 2024

Amidst burgeoning interest, atomically precise copper nanoclusters (Cu NCs) have emerged as a remarkable class of nanomaterials distinguished by their unparalleled reactivity. Nonetheless, the synthesis hydride-free Cu NCs and role stable catalysts remain infrequently explored. Here, we introduce facile synthetic approach to fabricate [Cu

Language: Английский

Citations

8
Luminescence “on-off-on” sensing of acute myocardial infarction biomarker miRNA-208a based on copper nanoclusters-MoS2 FRET system DOI
Suzhen Zhang,

Danling Mei,

Hongming Fang

et al.

Microchimica Acta, Journal Year: 2025, Volume and Issue: 192(3)

Published: Feb. 15, 2025

Language: Английский

Citations

0
Deciphering Electrocatalytic Activity in Cu Nanoclusters: Interplay Between Structural Confinement and Ligands Environment DOI Creative Commons
Sourav Biswas,

Yamato Shingyouchi,

Maho Kamiyama

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Ligand-protected copper nanoclusters (Cu NCs) with atomic precision have emerged rapidly due to their fascinating structural architectures and versatile catalytic properties, making them ideal for investigating structure-activity relationships. Despite potential, challenges such as stability issues limited diversity restricted deeper exploration. In this study, three distinct Cu NCs are synthesized using a one-pot reduction strategy by carefully modifying reaction conditions. Intriguingly, the same p-toluenethiol ligand produces two different geometries, while varying ligands m-aminobenzethiol-yielded clusters similar geometric architectures. These evaluated electrocatalytic CO2 reduction, uncovering diverse activities product selectivity. Experimental theoretical analyses reveal that interplay between core structure confinement surface environment governs behavior. Specifically, Cu11 NC exhibits selectivity toward HCOOH production (FEHCOOH∼45% at -1.2 V vs RHE), whereas substituting m-aminobenzethiol shifted competitive side (FEH2∼82% RHE). Conversely, altering geometry of Cu18 retaining decreases (FEHCOOH∼35% findings highlight tunability tailored applications through precise control chemistry.

Language: Английский

Citations

0
Advancing electrochemical CO2 reduction with group 11 metal nanoclusters for renewable energy solutions DOI Creative Commons
Sourav Biswas,

Yamato Shingyouchi,

Masaki Ogami

et al.

EcoEnergy, Journal Year: 2024, Volume and Issue: 2(3), P. 400 - 418

Published: July 10, 2024

Abstract Understanding the intricate relationship between structure and properties is paramount in distinguishing nanocluster (NC) materials from their counterparts. Despite progress synthesizing new NCs, sluggish exploration of potential applications persists due to difficulty stabilizing these materials. However, recent investigations have unveiled remarkable efficacy as catalysts electrochemical CO 2 reduction reactions, surpassing traditional This discovery, addressing urgent global concerns, has quickly drawn significant attention this field, leading its rapid expansion. Hence, there an need outline research landscape pinpoint effective strategies, marking a advancement. In context, our endeavor dedicated offering researchers thorough understanding recently synthesized NC We aim elucidate distinct structural architectures associated essential for catalyst design. envision that systematic review will serve guiding beacon future endeavors burgeoning field.

Language: Английский

Citations

2
Luminescence “on-off-on” sensing of acute myocardial infarction biomarker miRNA-208a based on copper nanoclusters-MoS 2 FRET system DOI Creative Commons
Suzhen Zhang,

Danling Mei,

Hongming Fang

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 12, 2024

Abstract MiRNA-208a is a molecular marker for the early stage of acute myocardial infarction (AMI), with satisfactory specificity and relatively short time window, making it highly suitable diagnosis AMI. In this study, we designed CuNCs-cDNA-MoS2 fluorescent probe established fluorescence resonance energy transfer (FRET) enzyme-free biosensor "on-off-on" detection miRNA-208a. The results showed that limit miRNA-208a was 900 pM, linear range 1 to 10 nM. Interestingly, after addition RNase inhibitor, serum were reduced 5 minutes 380 respectively. It also has wide (1–20 nM), recovery rate 98.13 101.20%. Compared traditional methods, strategy simple, rapid, sensitive, cost-effective. summary, FRET-based sensor provides high-performance method detecting

Language: Английский

Citations

0