Published: Jan. 1, 2024
Language: Английский
Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4164 - 4164
Published: Nov. 30, 2024
The dietary index for gut microbiota (DI-GM) is a newly proposed metric assessing diet quality, and its relationship with biological age unclear. We hypothesize that consuming foods conducive to healthy environment may decelerate aging.
Language: Английский
Citations
5
The journal of nutrition health & aging, Journal Year: 2025, Volume and Issue: 29(3), P. 100488 - 100488
Published: Jan. 15, 2025
This study seeks to determine the association between serum uric acid (SUA) and accelerated aging among middle-aged older adults in China, as well assess relationship SUA trajectories risk of aging. We utilized data from China Health Retirement Longitudinal Study (CHARLS), selecting participants who completed follow-ups 2011 2015. Biological age was estimated using Klemera-Doubal method, determined by calculating difference an individual's biological their chronological age. Logistic regression models were employed analyze baseline levels, trajectories, aging, adjusting for potential confounding factors. A total 3,520 (average 59.00 years) included. The results indicated a significant linear positive correlation levels Compared group with lowest those highest had markedly increased (OR = 1.5, 95% CI: 1.23-1.83, P < 0.001). Further longitudinal analysis suggested that maintaining low level associated reduction indicates elevated constitute factor adults. Maintaining at low-level help slow down These findings highlight importance monitoring this demographic, providing scientific basis developing interventions delay
Language: Английский
Citations
0
Clinical Nutrition, Journal Year: 2025, Volume and Issue: 46, P. 52 - 59
Published: Jan. 20, 2025
Language: Английский
Citations
0
Journal of Nutrition, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Language: Английский
Citations
0
Biogerontology, Journal Year: 2025, Volume and Issue: 26(2)
Published: April 1, 2025
This study aimed to investigate the relationship between total antioxidant capacity (TAC) and phenotypic age acceleration (PhenoAgeAccel), a measure of accelerated biological aging, using data from National Health Nutrition Examination Survey (NHANES). Data 2003-2010 NHANES surveys, encompassing 16,395 participants, were analyzed. Principal component analysis (PCA) was used reduce dimensionality. Multivariate logistic regression models employed evaluate association TAC vitamins (α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein-zeaxanthin, vitamin A, C, E) with PhenoAgeAccel, adjusting for demographic, lifestyle, clinical factors. Smoothed curve fitting threshold effects conducted explore nonlinear log-transformed PhenoAgeAccel. Subgroup analyses performed assess potential effect modifiers based on age, gender, race, education, smoking, alcohol use, diabetes, hypertension, hyperlipidemia. The weak correlations original variables prevent PCA effectively capturing primary variability within data. Higher significantly inversely associated PhenoAgeAccel in both unadjusted adjusted models. Participants second tertile (T2) exhibited 11% lower odds compared those first (T1) (OR = 0.89, 95% CI: 0.81-0.98, P 0.0176). Intake several vitamins, including α-carotene, E, also A observed, significant protective specific range TAC. revealed no modification by most factors, except consumption. is closely higher exhibiting range, particularly among males, smokers, consumer. These findings underscore value mitigating aging process.
Language: Английский
Citations
0
Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: April 12, 2025
This study investigates the association between dietary methyl donor nutrients intake and phenotypic aging. cross-sectional comprised 27,211 adult participants from NHANES 2005-2018. The methyl-donor nutritional quality index (MNQI) was calculated by assessing of seven nutrients: protein, folate, choline, riboflavin, vitamin B6, B12, zinc. Phenotypic age acceleration (PhenoAge.Accel) using biochemical markers to assess biological Weighted generalized linear regression models were utilized associations MNQI PhenoAge.Accel, impact different demographic health characteristics evaluated through interaction effect tests. After adjusting for various potential confounding factors, a significant negative found PhenoAge.Accel (β = - 0.66; 95% CI 0.91, 0.40; P < 0.0001), indicating that an increase in is associated with slowdown PhenoAge.Accel. Furthermore, subgroup analysis indicated stronger negatively males 0.94; 1.36, 0.52) interactions (Pinteraction 0.02). In populations, PhenoAge Accel, suggesting choosing high-quality foods can help develop effective strategies enhance healthy longevity.
Language: Английский
Citations
0
Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12
Published: May 1, 2025
Background Frailty severely impacts patients’ quality of life and imposes a significant burden on healthcare systems. The Dietary Index for Gut Microbiota (DI-GM) is an emerging dietary indicator, its association with frailty has not been thoroughly investigated. Methods This study utilized data from NHANES 2007–2018 assessed the between DI-GM using multivariable weighted logistic regression, restricted cubic splines (RCS), subgroup analysis, mediation after adjusting relevant covariates. Results results indicate negative correlation frailty, each standard unit increase in reducing risk by 6% (OR = 0.940 [0.899, 0.984]). at different quartiles showed strong dose–response relationship, highest quartile showing 21.6% reduction. RCS analysis revealed linear relationship frailty. Subgroup suggested that age smoking status may influence Furthermore, albumin high-density lipoprotein (HDL) played mediating roles accounting 30.34 9.05% total effect, respectively. Conclusion negatively associated risk, HDL mediate this association. Improving be effective strategy risk.
Language: Английский
Citations
0
Published: Jan. 1, 2024
Language: Английский
Citations
0