Plant-Derived Extracellular Vesicles: Natural Nanocarriers for Biotechnological Drugs

Processes, Journal Year: 2024, Volume and Issue: 12(12), P. 2938 - 2938

Published: Dec. 23, 2024

Plant-derived extracellular vesicles (PDEVs) are lipid bilayer nanoparticles, naturally produced by plant cells, with sizes ranging from 50 to 500 nm. Recent studies have highlighted their great potential in the biotechnological and medical fields, due natural origin, high biocompatibility intrinsic therapeutic properties. PDEVs contain a complex biological cargo of proteins, lipids, nucleic acids secondary metabolites, including antioxidants anti-inflammatory molecules, making them ideal for biomedical applications such as drug delivery. These play key role intercellular communication gene regulation, proving be particularly promising personalized medicine. ability improve stability bioavailability, optimizing targeted release minimizing side effects. Despite some challenges, compositional variability need standardized protocols, at gunsight innovative research aimed improving loading capacity specificity. This review aims provide comprehensive overview PDEVs, exploring structure, isolation methods, functional characteristics, applications, highlighting advantages over synthetic nanoparticles animal-derived vesicles, leading an sustainable solution development new approaches.

Language: Английский

Scalable membrane-based processes to isolate extracellular vesicles from lemon juice

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 133097 - 133097

Published: April 1, 2025

Language: Английский