Electron Donor–Acceptor Complex-Driven Divergent Routes to α-Amino Bicyclopentyl Iodides and Methylene Cyclobutanols DOI

Vinjamuri Srinivasu,

Koustav Pal,

S. Giri

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 24, 2024

Amines are essential due to their structural diversity and biological significance. Introducing the valuable bicyclopentane (BCP) moiety at α-position of amines offers a promising strategy for developing novel bioactive compounds. This study outlines divergent synthesis approach generate α-amino-functionalized bicyclopentyl iodides methylene cyclobutanols under mild environmentally sustainable conditions. By employing an electron donor-acceptor (EDA) complex between amine inexpensive readily available inorganic base Cs

Language: Английский

Visible-light induced selenocyclization of 2-ethynylanilines under ambient conditions: simple FeBr3 as a dual-functional catalyst DOI
Binbin Huang,

Xinye Tang,

Jiawei Yuan

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(30), P. 6198 - 6204

Published: Jan. 1, 2024

Reported herein is a visible-light induced selenocyclization of 2-ethynylanilines under ambient conditions, with simple FeBr 3 as dual-functional catalyst.

Language: Английский

Citations

7
Direct C(sp3)-H functionalization with aryl and alkyl radicals as intermolecular hydrogen atom transfer (HAT) agents DOI
Jia‐Lin Tu, Binbin Huang

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Recent years have witnessed the emergence of direct intermolecular C(sp

Language: Английский

Citations

7
Visible-light-mediated synthesis of polysubstituted pyrroles via CAr–I reduction triggered 1,5-hydrogen atom transfer process DOI
Junlei Wang,

Qinglin Xie,

Guocheng Gao

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(16), P. 4522 - 4528

Published: Jan. 1, 2024

A novel strategy for the construction of polysubstituted pyrroles has been developed through visible-light-induced single-electron reduction C Ar –I bonds and following 1,5-hydrogen atom transfer (HAT) process.

Language: Английский

Citations

6
Visible-Light-Driven Catalytic Dehalogenation of Trichloroacetic Acid and α-Halocarbonyl Compounds: Multiple Roles of Copper DOI Creative Commons

Abigail J. Thillman,

Erin C. Kill,

Alexander N. Erickson

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: 15(5), P. 3873 - 3881

Published: Feb. 19, 2025

Herein, we report the reaction development and mechanistic studies of visible-light-driven Cu-catalyzed dechlorination trichloroacetic acid for highly selective formation monochloroacetic acid. Visible-light-driven transition metal catalysis via an inner-sphere pathway features dual roles species in photoexcitation substrate activation steps, a detailed understanding their is crucial further light-driven catalysis. This catalytic method, which environmentally desired ascorbic as hydrogen atom source water/ethanol solvent, can be applied to dehalogenation variety halocarboxylic acids amides. Spectroscopic, X-ray crystallographic, kinetic have revealed mechanism copper photoexcitation, thermal first C–Cl bond, excited-state second bond chlorine transfer.

Language: Английский

Citations

0
A Novel 2-Methylimidazole Promoted Oxyacyloxylation of α-Hydroxy Ketones and Anhydrides: An Easy Access to α-Acyloxy Ketones DOI Open Access

Shi‐Wei Yu,

Zhonghao Li,

Miao-Xin Li

et al.

Catalysts, Journal Year: 2024, Volume and Issue: 14(11), P. 811 - 811

Published: Nov. 11, 2024

An efficient and operationally simple method for the synthesis of α-acyloxy ketones through readily available 2-methylimidazole-promoted reaction α-hydroxy anhydrides is developed. In reaction, act as both a substrate solvent. The new features good tolerance, mild conditions, accessible starting materials, excellent yields, providing facile green access to targets. Importantly, also avoids use reagents with pungent odors, such pyridine, in traditional esterification, which may promote development organocatalysis using nitrogen-containing heterocyclic compounds catalysts.

Language: Английский

Citations

1
Z-Selective hydrosulfoxidation of alkynes with thiols and hydrogen peroxide Enabled by a Multifunctional octamolybdate DOI

Xianghua Zeng,

Hao Xu, Yongge Wei

et al.

Journal of Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 115892 - 115892

Published: Dec. 1, 2024

Language: Английский

Citations

1
Electron Donor–Acceptor Complex-Driven Divergent Routes to α-Amino Bicyclopentyl Iodides and Methylene Cyclobutanols DOI

Vinjamuri Srinivasu,

Koustav Pal,

S. Giri

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 24, 2024

Amines are essential due to their structural diversity and biological significance. Introducing the valuable bicyclopentane (BCP) moiety at α-position of amines offers a promising strategy for developing novel bioactive compounds. This study outlines divergent synthesis approach generate α-amino-functionalized bicyclopentyl iodides methylene cyclobutanols under mild environmentally sustainable conditions. By employing an electron donor-acceptor (EDA) complex between amine inexpensive readily available inorganic base Cs

Language: Английский

Citations

0