Facet-Engineered Copper Electrocatalysts Enable Sustainable NADH Regeneration with High Efficiency DOI
Shuo Sun, Yizhou Wu,

Yunxuan Ding

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: 147(19), P. 16630 - 16641

Published: April 30, 2025

Electrochemical regeneration of the nicotinamide cofactor (NADH) provides a sustainable approach to enzymatic reactions. However, low productivity and selectivity bioactive 1,4-NADH limit its broad applications. The hydrogenation NAD+ at electrode surface is strongly coupled conformation adsorbed NAD*, formation hydrogen (Had), Had transfer NAD*. Therefore, searching for materials with suitable NAD* conformation, energy, rapid becomes key task research. In this study, (111) facet Cu was found exhibit higher 86.4%, compared 50.4% 57.4% (100) (110) facets, respectively. Density functional theory (DFT) calculations revealed that high Cu(111) stemmed from favorable reduced barrier. Subsequently, nanowire (111)-dominant abundant grain boundaries, Cugb(111), constructed. kinetic analysis DFT demonstrated boundaries reduce reaction barrier formation. A record-high 73.5 μmol h-1 cm-2 achieved by while well-maintained 84.7%. This study elucidates effects crystal facets on regulating 1,4-NADH, providing pathway renewable energy-powered, high-efficiency green biomanufacturing.

Language: Английский

Copper‐Functionalized MIL‐101(Cr): An Efficient, Reusable, and Heterogeneous Catalyst for Chan–Lam Coupling and Amide Bond Formation DOI

Rona Moni Bora,

Lenida Kyndiah, Priyanka Borah

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(11)

Published: March 1, 2025

Abstract Efficient protocols for the synthesis of secondary amines using phenylboronic acid and aniline via Chan–Evan–Lam coupling reaction amides by oxidative amidation aldehydes with utilizing heterogeneous, recyclable MIL‐101(Cr)‐SB‐Cu catalyst have been developed. has synthesized post‐synthetic modification amino‐functionalized MIL‐101(Cr). Various spectroscopic analytical methods, such as FT‐IR, PXRD, SEM, TEM, EDX, XPS, ICP‐OES, TG were used to characterize catalyst. The showed excellent catalytic activity provided good yields desired products under mild conditions. can be reused up five consecutive runs without significant loss in its activity. Low loading, easy work‐up, gram‐scale synthesis, a simple preparation are some other advantages this approach.

Language: Английский

Citations

0
Facet-Engineered Copper Electrocatalysts Enable Sustainable NADH Regeneration with High Efficiency DOI
Shuo Sun, Yizhou Wu,

Yunxuan Ding

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: 147(19), P. 16630 - 16641

Published: April 30, 2025

Electrochemical regeneration of the nicotinamide cofactor (NADH) provides a sustainable approach to enzymatic reactions. However, low productivity and selectivity bioactive 1,4-NADH limit its broad applications. The hydrogenation NAD+ at electrode surface is strongly coupled conformation adsorbed NAD*, formation hydrogen (Had), Had transfer NAD*. Therefore, searching for materials with suitable NAD* conformation, energy, rapid becomes key task research. In this study, (111) facet Cu was found exhibit higher 86.4%, compared 50.4% 57.4% (100) (110) facets, respectively. Density functional theory (DFT) calculations revealed that high Cu(111) stemmed from favorable reduced barrier. Subsequently, nanowire (111)-dominant abundant grain boundaries, Cugb(111), constructed. kinetic analysis DFT demonstrated boundaries reduce reaction barrier formation. A record-high 73.5 μmol h-1 cm-2 achieved by while well-maintained 84.7%. This study elucidates effects crystal facets on regulating 1,4-NADH, providing pathway renewable energy-powered, high-efficiency green biomanufacturing.

Language: Английский

Citations

0