Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 246, P. 114373 - 114373
Published: Nov. 14, 2024
Language: Английский
Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
This review highlights recent technological advances for progress in particle manipulation under X-force fields, and forecasts the trajectory of future developments.
Language: Английский
Citations
0
Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106279 - 106279
Published: March 1, 2025
Language: Английский
Citations
0
Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: March 25, 2025
InfoMetricsFiguresRef. Analytical ChemistryASAPArticle This publication is Open Access under the license indicated. Learn More CiteCitationCitation and abstractCitation referencesMore citation options ShareShare onFacebookXWeChatLinkedInRedditEmailBlueskyJump toExpandCollapse ReviewMarch 25, 2025Acoustofluidics: Technology Advances Applications from 2022 to 2024Click copy article linkArticle link copied!Toktam GodaryToktam GodaryC. Eugene Bennett Department of Chemistry, West Virginia University, Morgantown 26506-6201, Virginia, United StatesMore by Toktam GodaryView BiographyBrandi BinkleyBrandi BinkleyC. Brandi BinkleyView Biographyhttps://orcid.org/0000-0003-1572-1364Zhengru LiuZhengru LiuC. Zhengru LiuView BiographyOlanrewaju AwoyemiOlanrewaju AwoyemiC. Olanrewaju AwoyemiView BiographyAmanda OverbyAmanda OverbyC. Amanda OverbyView BiographyHerbi YuliantoroHerbi YuliantoroC. Herbi YuliantoroView BiographyBethany J. FikeBethany FikeC. Bethany FikeView BiographySydney AndersonSydney AndersonC. Sydney AndersonView BiographyPeng Li*Peng LiC. States*should be addressed P.L. ([email protected]).More Peng LiView Biographyhttps://orcid.org/0000-0002-8332-7142Open PDFAnalytical ChemistryCite this: Anal. Chem. 2025, XXXX, XXX, XXX-XXXClick citationCitation copied!https://pubs.acs.org/doi/10.1021/acs.analchem.4c06803https://doi.org/10.1021/acs.analchem.4c06803Published March 2025 Publication History Received 15 December 2024Accepted 13 2025Revised 27 February 2025Published online 25 2025review-article© The Authors. Published American Chemical Society. licensed CC-BY 4.0 . License Summary*You are free share (copy redistribute) this in any medium or format adapt (remix, transform, build upon) material for purpose, even commercially within parameters below:Creative Commons (CC): a Creative license.Attribution (BY): Credit must given creator.View full license*DisclaimerThis summary highlights only some key features terms actual license. It not has no legal value. Carefully review before using these materials. underCC-BY share(copy adapt(remix, below: Attribution *DisclaimerThis creator. View ACS Publications© SocietySubjectswhat subjects Article automatically applied Subject Taxonomy describe scientific concepts themes article. Fluids Liquids Microparticles Nanoparticles Quantum mechanics Special IssuePublished as part Chemistry special issue "Fundamental Applied Reviews 2025".Acoustofluidics, interplay acoustics fluid dynamics, experienced exponential growth past decade. Acoustic waves result vibration oscillation particles through which they propagate. These propagate but also exert forces on it objects their pathway. Through careful engineering wave generation propagation, often conjunction with microfluidic platforms, acoustofluidics enables precise manipulation control wide range at microscale, including biological fluids. Two typical types acoustofluidic devices bulk acoustic (BAW) surface (SAW) devices, classified based mode propagation. A BAW device includes piezoelectric transducer resonant chamber, while SAW requires patterned electrodes top substrate. Both have demonstrated extraordinary versatility effectiveness, serving powerful tools across diverse application areas such biomedical diagnostics, materials synthesis, tissue engineering. major advancements spanning January November 2024, emphasizing both technological innovations expansion domains. By showcasing breadth field ingenuity behind its numerous breakthroughs, we aim provide readers comprehensive understanding current state future directions.Advances DevelopmentClick section linkSection copied! Device FabricationFabricating methods essential functionality commercialization devices. While standard microfabrication procedures still apply, factors channel, coupling layer, matching wavelength geometry, properties unique devices.Channel impact energy efficiency Acikgoz et al. (1) evaluated effectiveness various use chip particle cell manipulation. studied include silicon, glass, epoxy fiberglass filling (FR4), polydimethylsiloxane (PDMS), poly(methyl methacrylate) (PMMA). study shows that PDMS PMMA most suitable purposes, silicon best high precision structural stability, glass good when optical clarity needed. Luzuriaga (2) reported acoustophoretic motion polystyrene can observed hybrid millifluidic resonator. resonators channels embedded hydrogel similar liquids. Fakhfouri (3) fabricated made dry film resist (DFR), improves reproducibility microchannels. generating streaming complements radiation effect, was able trap nanoparticles small 200 nm.To generate (BAW), Fuchsluger (4) lateral modes plate used an resonator device. were perform rapid focusing excited frequency 540 kHz. Qiu (5) potential lead-free Using common transducers lead zirconate titanate results environmental biocompatibility issues. experiments simulations, researcher match low power better intermediate powers. (6) position They found placing side actuation led 4-fold increase density, due symmetry breaking improvement conversion efficiency.Using interdigital (IDTs) dominant way (SAWs) IDTs "lift-off" procedure, lengthy process access clean room facilities. Rich (7) fabricating aerosol jet printing (Figure 1A). successfully printed different silver nanowires, graphene, poly(3,4-ethylenedioxythiophene) polystyrenesulfonate (PEDOT:PSS). then comparable concentration. Wang Qian (8) femtosecond laser micromachining fabricate method generates steel foil form mask directly evaporating metal substrate mask. resulting functionalities. Zhang (9) introduced novel IDT design termed unapodization. Unapodization removes apodization creating laterally uniform reduced variations smoothed-out amplitudes surface.Figure 1Figure 1. (A) Aerosol IDTs. Reprinted permission Macmillan Publishers Ltd.: NATURE, Rich, J.; Cole, B.; Li, T.; Lu, Fu, H.; Smith, B. N.; Xia, Yang, S.; Zhong, R.; Doherty, L.; Kaneko, K.; Suzuki, Tian, Z.; Franklin, A. D.; Huang, T. Microsystems & Nanoengineering 10 (1), 2. (ref (7)). Copyright 2024 International (http://creativecommons.org/licenses/by/4.0/). (B) Reusable microchannel fabrication thin layer polyamide. IOP Publishing, Mikhaylov, Martin, M. Dumcius, P.; Wang, Wu, F.; Zhang, X.; Akhimien, V.; Sun, C.; Clayton, A.; Y.; Ye, Dong, X. Reconfigurable Portable Acoustofluidic System Based Flexible Printed Circuit Board Manipulation Microspheres. Micromechanics Microengineering 2021, 31 (7), 074003. 10.1088/1361-6439/ac0515. (16)). 2021 (http://creativecommons.org/licenses/by/4.0/).High Resolution ImageDownload MS PowerPoint SlideSurface droplet Ning (10) self-assembled monolayers (SAMs) 1H,1H,2H,2H-perfluorododecyltrichlorosilane (FDTS) LiNbO3 substrates enhance performance. FDTS SAMs deposited onto via chemical vapor deposition, hydrophobic surface. Then compared untreated there driving speed therefore faster more liquid jetting. Al-Ali (11) 3-(trimethoxysilyl) propyl methacrylate (TMSPMA) silane treatment attachment substrates. modification strategy involved oxygen plasma alter chemistry improving ability bond other materials.Due cost substrates, growing need developing reusable Kuruoglu (12) detach permanent bonding between PDMS. immersing 0.1 M potassium hydroxide solution 2 h effectively significant deterioration channel after 3 cycles bonding-detachment. Another achieve separating fluidic necessitates efficient layer. Park (13) thickness phenomena. >8 times wave, will absorb almost all heat. Therefore, ensure force microchannel, needs controlled. Kolesnik (14) investigated optimal superstrate thickness. Results indicated 0.55 maximized coupling. Chang (15) explored n-dodecane performance microchips. With viscosity water lower tension higher boiling point, offers properties. allow reduce friction microchip fluid. n-Dodecane enhances transfer fluid, Yang co-workers (16) mechanically clamping (IDEs) circuit board (PCB) achieved reusability microchannel. polyamide 1B). allows formation flexible structures adapted applications.Fabricating first step wearable many vivo applications. Zahertar (17) consist layers polymer. Overall, combination metallic polymer advantages. Metallic ideal flexibility tuning Pang (18) Rayleigh shear horizontal SAWs generated simultaneously inclined ZnO film. two work together dual approach providing versatile platform.Advances Particle ManipulationClick copied!Acoustics been excellent tool manipulating nonbiological fluids contactless manner. mainly controlling (ARF) exerted particle. accurate characterization ARF experimental conditions important. Liu (19) proposed lookup table determining examining acoustophoresis discrete phase modulated standing fields. Edthofer (20) employed two-step measure relative mobility beads experiments. acousto-mechanical could quantitatively analyzed, showed large spread properties, indicating extra normalization may necessary calibration. FocusingFocusing continuous flow one early demonstrations Recent studies focused expanding targets. (21) developed square single source align focus nonspherical cells, ellipsoidal Euglena gracilis. 96% orientation width 7.8 μm rates up μL/min. Hammarstrom (22) protein microcrystal real-time monitoring during serial crystallography, achieving 200-fold concentration increase. (23) microflow cytometer tunnel fluorescence enhancement microreflector detection occur without sheath improved intensity AlN-Mo 1.8 8.3-fold over Si SiO2 respectively. further size had velocities exited region. phenomenon, system differentiate transit time region.Another important area improve submicron particles. Hemptinne (24) utilized frequency-sweeping techniques multiple parallel channels, overcoming influence variabilities resonance each channel. In focusing, streaming-induced drag act against focusing. When large, dominates force. However, (<1 μm), become so disrupts Gerlt (25) 1 round capillaries (500 ID) rate 5 Their simulation operating frequencies near maintaining sufficient Similarly, Lee (26) induced unidirectional vortex pattern 100 capillary 0.25 following work, smaller (50 μm) (14.9 MHz) nm ∼2 (27) Harshbarger (28) implemented feedback automatic optimization scientist operators, superior performance, 600 selecting working frequency. Devendran (29) diffractive-acoustic (DASAW) author DASAW configuration critical reducing inherent effects maintained. SortingRichter (30) activated absorbance sorter sorting tartrazine dye droplets concentrations (30 80 μM). Biconcave microlenses integrated into detection, traveling (TSAW) deflection 1000 droplets/s. Nawaz (31) utilizes (FTSAW) deformability cytometry (RT-DC) sort cells physical throughput. (FIDT)-based RT-DC platform (soRT-DC) tested white blood TBC-depleted raw diluted whole blood, purity greater than 92% viability 90%. Sethia (32) TSAWs image-based human stem cell-derived β clusters (SC-β clusters) size. SC-β ranging diameters ∼100–500 passed inlet device, pictures taken 2× magnification microscope. For separation cutoff 250 μm, setup gave 78–90% throughput 0.2 clusters/s. (33) geometrically defined active region selectively interest central stream leaving unwanted unaffected. SeparationAcoustofluidics label-free label-based separation. To date, separate kinds mammalian bacteria, viruses, extracellular vesicles. separations, possible acoustically differences size, compressibility. Wu (34) power-controlled systems microparticle separation, utilizing (SSAWs) optimize efficiency. agreement theoretical predictions microparticles varying sizes. During years, reports tilted-angle (taSSAW) taSSAW takes advantage angle direction SSAW overcome distance limit conventional Several groups numerical analysis tilt angle, prefocusing width, aperture length IDTS (35,36) (37) combined bipolar electrode-based DEP mechanical 94% maintained THP-1 yeast cells. Xue (38) divergent taSSAAW resolution. 91% success myelogenous leukemia line K562 natural killer NK92, density (39) numerically employs spiral cell/particle taSSAWs, increasing particles/cells properties.In addition taSSAW, several new designs Xia (40) designed Bessel (BIDTs) create beam 2A). Compared ∼5 intensities region, leading nanoparticle 30, 100, 400 successful enrichment SARS-CoV-2 virus saliva samples. (41) leveraged leaky pair virtual pillars employing excitation frequency, orthogonal original formed, along direction. Bigger experience bigger pass pillar. After repeated cycle, achieved. exosomes (60–80 larger ones (90–150 96%. (42) gigahertz arc-shape induce strong edge Combining trapping effect microvortices, capture 30 particles, directing 150 desired outlet. Ang (43) ceiling PDMS-based nanosieve Due impedance loss thereby 30-fold ceiling.Figure 2Figure Reproduced Becker, Wei, Rufo, Qian, Chen, Gu, Lee, P. Wong, D. W.; L. Virus Isolation Beam Excitation Separation Technology. Nano 18 (33), 22596–22607. (40)). Cell pairing Fourier synthesized harmonic resolution field. Mai, Bachman, P.-H.; M.; Harmonic Acoustics Dynamic Selective Manipulation. Nat. Mater. 2022, 21 (5), 540–546. (53)). 2022. (C) BEACON uses patterns holograms patterning. Acoustography Engineering Control Node: BEACON. Yu, Zhu, Upreti, Xu, Advanced Science 2403742. (59)) SlideFor size-based Khan (44) differential torques, enabling spherical prolate recovery purity. Undvall (45) inertial
Language: Английский
Citations
0
Biomicrofluidics, Journal Year: 2025, Volume and Issue: 19(3)
Published: May 1, 2025
Manipulation of red blood cells (RBCs) in microscale has proven to play a pivotal role various applications, such as disease diagnosis and drug delivery. Over the past decades, capabilities manipulation techniques have evolved from simple particle organisms, with numerous microfluidic-based research tools being developed for RBC manipulation. This review first introduces reported their principles, including passive microfluidic methods based on microstructures hydrodynamics, well active acoustic, optical, electrical techniques. It then focuses application scenarios these micro-scale manipulation, investigation mechanical properties, preparation carriers, control rotation, lysis. Finally, future prospects are discussed. offers comprehensive comparison techniques, aiming provide researchers different fields broad perspective guide continued development applications. seeks help diverse backgrounds stay informed about latest trends advancements field.
Language: Английский
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0
Lab on a Chip, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
All-inorganic cesium lead halide perovskites have garnered significant attention owing to their favorable optical properties. Microfluidics-based acoustic mixers are capable of achieving rapid nucleation and ultrafast growth kinetics. Nevertheless, conventional rely on the response microstructures field for mixing fluids, majority these disturbances occur in central region channel, with minimal impact fluid within side walls. This paper proposes a novel mixer that combines effects sharp corners bubbles field, thereby producing effective disturbance throughout channel. The combined effect enables micromixer achieve complete at different inlet flow ratios times as low 5 ms. superiority controlling nanocrystal formation stage was further validated through synthesis chalcogenide nanocrystals using LARP method. millisecond time facilitated subsequent growth. results demonstrate green luminescence intensity 520 nm samples synthesized is 118% higher than an intermittent reactor. broadens range applications offers promising avenue large-scale continuous high-quality lead-halide perovskite (NCs).
Language: Английский
Citations
0
Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 246, P. 114373 - 114373
Published: Nov. 14, 2024
Language: Английский
Citations
0