TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: 183, P. 118112 - 118112
Published: Dec. 19, 2024
Language: Английский
Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
Centrifugal microfluidics, with its advantages of rapid and precise fluid control without the need for external pressure, is widely applied in point-of-care testing.
Language: Английский
Citations
3
ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 8, 2025
Nanomedicine is revolutionizing precision medicine, providing targeted, personalized treatment options. Lipid-based nanomedicines offer distinct benefits including high potency, targeted delivery, extended retention in the body, reduced toxicity, and lower required doses. These characteristics make lipid-based nanoparticles ideal for drug delivery areas such as gene therapy, cancer treatment, mRNA vaccines. However, traditional bulk synthesis methods LNPs often produce larger particle sizes, significant polydispersity, low encapsulation efficiency, which can reduce therapeutic effectiveness. issues primarily result from uneven mixing limited control over formation during synthesis. Microfluidic technology has emerged a solution, precise size, uniformity, efficiency. In this mini review, we introduce state-of-the-art microfluidic systems nanoparticle functionalization. We include working principles of different types systems, use LNP synthesis, cargo encapsulation, nanomedicine delivery. end, briefly discuss clinical enabled by devices.
Language: Английский
Citations
2
Physics of Fluids, Journal Year: 2025, Volume and Issue: 37(3)
Published: March 1, 2025
This paper presents a microfluidic approach that dynamically controls the hydrodynamic flow and streamlines to enable complex multi-particle manipulations within single device. The combines design of flow-through Hele–Shaw cell together with an optimization procedure find priori optimal particle pathlines, effective proportional–integral–derivative (PID) feedback controller provide real-time control over manipulations. In device, particles are manipulated forces, by using uniform through three inlets perpendicular cell. device injecting or extracting fluid inlets. geometry allows fast accurate prediction trajectory, meaning only simple PID is required correct for deviations. robustness this demonstrated implementing multiple functions including trapping, sorting, separation, assembly. affords manipulation, maximum error on order diameter particle.
Language: Английский
Citations
0
Frontiers in Natural Products, Journal Year: 2025, Volume and Issue: 4
Published: March 13, 2025
Marine algae are a rich and underexplored source of haloperoxidases, enzymes with wide ranging applications in biocatalysis, pharmaceuticals, environmental bioremediation due to their ability catalyze the halogenation organic compounds. This review focuses on recent advancements purification haloperoxidases from marine algae, highlighting both traditional innovative methods. We discussed limited exploration green algal potential for discovering novel unique properties. The examines advantages disadvantages chromatographic techniques, such as ion-exchange, size exclusion, affinity chromatography, explores emerging alternatives, including aqueous two-phase systems (ATPS) microfluidic systems, improving enzyme yield, purity, stability. use ATPS address challenges posed by alginate-rich brown is emphasized, along optimization strategies scaling up processes. growing importance sustainable chemistry approaches minimize impact while achieving high efficiency also discussed. By analyzing current identifying knowledge gaps, suggesting future research directions, this aims provide meaningful insights into industrial thereby stimulating further innovation field.
Language: Английский
Citations
0
TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118236 - 118236
Published: March 1, 2025
Language: Английский
Citations
0
Published: Jan. 19, 2025
Language: Английский
Citations
0
Physics of Fluids, Journal Year: 2025, Volume and Issue: 37(3)
Published: March 1, 2025
Precise microflow manipulation remains a significant challenge in microfluidics, despite its broad applications biomedical engineering. Metamaterial-inspired microstructures offer promising approach to advanced flow regulation, enabling precise control over fluid velocity, trajectories, and multifunctional microenvironments. This study explores the fundamental mechanisms of microfluidic manipulation, emphasizing tunable theory, disturbances induced by metamaterial microelements, regulation capabilities macroscopic topological arrays. Specifically, we introduce velocity enhancement model, direction coupled velocity-direction modulation along with their implementation mechanisms. By constructing multiscale coupling framework that integrates microscopic perturbations dynamics, this work systematically examines interplay between localized fluid–structure interactions global patterns. Leveraging approach, reveal synergistic microstructural effects enable behavior. These findings advance understanding metamaterial–fluid microsystems provide practical solutions for high-precision applications, including rapid diagnostics organ-on-chip platforms.
Language: Английский
Citations
0
ACS Materials Letters, Journal Year: 2025, Volume and Issue: unknown, P. 2172 - 2180
Published: May 7, 2025
Language: Английский
Citations
0
TrAC Trends in Analytical Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 118124 - 118124
Published: Dec. 1, 2024
Language: Английский
Citations
1
RSC Advances, Journal Year: 2024, Volume and Issue: 14(47), P. 34586 - 34593
Published: Jan. 1, 2024
Streamlined production of micro-patterned electrodes using 3D-printed shadow masks provides a faster, cost-effective solution for rapid prototyping and iterative design, supporting the advancement diverse lab-on-chip applications.
Language: Английский
Citations
0