Solid State Ionics, Journal Year: 2024, Volume and Issue: 417, P. 116714 - 116714
Published: Oct. 10, 2024
Language: Английский
Solid State Ionics, Journal Year: 2024, Volume and Issue: 417, P. 116714 - 116714
Published: Oct. 10, 2024
Language: Английский
Food Chemistry, Journal Year: 2024, Volume and Issue: 462, P. 140962 - 140962
Published: Aug. 23, 2024
Language: Английский
Citations
9Nanoscale Advances, Journal Year: 2024, Volume and Issue: 7(1), P. 13 - 41
Published: Nov. 21, 2024
This review article discusses and summarizes the synthesis applications of luminescent metal–organic frameworks (MOFs) for sensing dipicolinic acid in biological water samples.
Language: Английский
Citations
8Journal of Inorganic and Organometallic Polymers and Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 15, 2025
Language: Английский
Citations
1Applied Organometallic Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 1, 2024
ABSTRACT Within the current challenges in medicinal chemistry, creation of novel and improved therapeutic agents stands out. 2‐Cyano‐3‐(thiophen‐2‐yl)prop‐2‐enethioamide (CTPTA) ligand was complexed with palladium (II) platinum ions within nanoscale molecular formula [M (CTPTA)Cl 2 ]. H O. The CTPTA its complexes were characterized by elemental analysis, UV–Vis spectra, FTIR, mass TGA, magnetic measurement, molar conductance technique. Analysis a scanning electron microscope (SEM) revealed that nanostructure dimension both is predominantly between 10 30 nm. functions as bidentate ligand, utilizing thione sulfur, cyanide nitrogen atoms. Density functional theory employed to analyze geometric structure properties complexes. Natural population (NPA) Mulliken (MPA) methods used calculate charge distribution. cytotoxic impact results all compounds on human liver cancer (HepG2) cell line satisfactory. also tested against gram‐negative gram‐positive bacteria vitro. findings docking study supported cytotoxicity antibacterial effects. antioxidant anti‐inflammation activities synthesized had great spectrum activity. preclinical pharmacokinetic studies albino rats newly studied achieved excellent antitumor results. This clear investigated parameters, especially amelioration AFP levels, weight, oxidative stress, lobular hepatic architecture injury.
Language: Английский
Citations
6Desalination, Journal Year: 2024, Volume and Issue: 592, P. 118183 - 118183
Published: Oct. 11, 2024
Language: Английский
Citations
5Analytical Methods, Journal Year: 2024, Volume and Issue: 16(38), P. 6474 - 6486
Published: Jan. 1, 2024
The evaluation of surface-engineered mono- and bimetallic MOFs in enzyme-mimic glucose sensors for biomedical applications covers recent advancements future perspectives their nanocomposites.
Language: Английский
Citations
4Crystals, Journal Year: 2025, Volume and Issue: 15(1), P. 70 - 70
Published: Jan. 12, 2025
Paracetamol-4,4′-bipyridine cocrystals were synthesized using a solution method, reflux grinding and ultrasonic method. The structures properties characterized through the utilization of single-crystal X-ray diffraction (SXRD), powder (PXRD), polarized light microscopy (PLM), thermogravimetric analysis (TGA), elemental (EA), infrared spectroscopy (IR). results show that four methods different cocrystal morphologies, but same structure coupled with notably high purity level. All featured strong hydrogen bonds formed between paracetamol,4,4′-bipyridine water molecules. An additional notable feature is presence π...π stacking interactions pyridine rings adjacent 4,4′-bipyridine solubility paracetamol (active pharmaceutical ingredient, API) was measured discussed. In dissolution experiment, showed much faster rate than API in simulated gastric fluid media (pH = 1.2). Furthermore, pharmacokinetic (PK) behavior investigated to evaluate effectiveness this strategy for enhancing oral absorption paracetamol. vitro vivo studies revealed paracetamol-4,4′-bipyridine possessed an excellent improved profile.
Language: Английский
Citations
0Journal of Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 1029, P. 123552 - 123552
Published: Jan. 31, 2025
Language: Английский
Citations
0Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(3)
Published: Feb. 7, 2025
ABSTRACT To advance our study on the GLUT's glucose recognition binding site and enhance effectiveness of targeted anticancer compounds based encouraging findings, glycogenated metal complexes have shown promise in combating colon cancer (HCT‐116) through salicylaldehyde‐D‐glucosamine Schiff base(H 2 L), we proceed with research utilizing various cell lines different ions known for their potent effect. Newly synthesized formulae Zn (HL) , (CH 3 ) Sn(HL) [Ru(L)(HL)H O].H O are directed against two (HCT‐116 Caco‐2). Different characterization techniques used to confirm structures. DFT was structurally optimize compounds. The particle size distribution performed all chelates. All revealed remarkable activities especially ligand Ru (III) complex recording IC 50 values 21.73 μg/mL HCT‐116 49.53 Caco‐2 lines, respectively. results showed that can attract sugar‐conjugated efficiency its confirmed evaluation GSH, SOD, MDA, NO, LDH levels. high affinity glycoconjugates DNA explored using electrophoresis. Additionally, chelates significant antimicrobial activity. (II) bactericidal activity strain Helicobacter pylori . docking simulation explore active amino acids participate biological interaction.
Language: Английский
Citations
0Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113351 - 113351
Published: March 1, 2025
Language: Английский
Citations
0