Carbon-based nanomaterials: interactions with cells, brain therapies, and neural sensing

Deleted Journal, Journal Year: 2025, Volume and Issue: 20(1)

Published: Feb. 21, 2025

Abstract Carbon nanomaterials (CNMs) are characterized by their extensive surface area and extraordinary electronic, thermal, chemical properties, offering an innovative potential for biomedical applications. The physicochemical properties of CNMs can be fine-tuned through functionalization to design the bio-nano interface, allowing controlled biocompatibility or specific bioactivity. This versatility offers a transformative approach addressing inherent limitations conventional brain therapies, which frequently demonstrate low efficacy significant adverse effects. review delves into recent advances in understanding intricate interactions between carbon nanostructures cellular systems, highlighting activity therapy neuronal sensing. We provide comprehensive analysis key nanostructures, including few-layer graphene (FLG), oxide (GO), quantum dots (GQD), single- multi-walled nanotubes (SWCNT MWCNT), nanohorns (CNH), nanodiamonds (CNDs), fullerenes (C 60 ). Their unique atomic configurations modifications examined, revealing underlying mechanisms that drive highlights how deep cells catalyze neurotherapeutic solutions. By leveraging address critical challenges such as crossing blood–brain barrier, improving therapeutic accuracy, minimizing side These have significantly improve treatment outcomes disorders, paving way new era targeted effective neurological interventions.

Language: Английский

Multifunctional selenium-doped carbon dots for modulating Alzheimer's disease related toxic ions, inhibiting amyloid aggregation and scavenging reactive oxygen species

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 139333 - 139333

Published: Dec. 1, 2024

Language: Английский