Recent advances in polydopamine-coated metal–organic frameworks for cancer therapy DOI Creative Commons

Jingchao He,

Guangtian Wang, Yongfang Zhou

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: April 1, 2025

The creation and development of classical multifunctional nanomaterials are crucial for the advancement nanotherapeutic treatments tumors. Currently, metal–organic frameworks (MOFs) modified with polydopamine (PDA) at forefront nanomedicine research, particularly in tumor diagnostics therapy, owing to their exceptional biocompatibility, expansive specific surface area, multifaceted functionalities, superior photothermal properties, which led significant advancements anti-tumor research. Consequently, a range anti-cancer strategies has been devised by leveraging capabilities MOFs, including intelligent drug delivery systems, photodynamic tailored microenvironment. In order gain deeper insight into role MOFs@PDA cancer diagnosis treatment, it is essential conduct comprehensive review existing research outcomes promptly analyze challenges associated biological applications. This will provide valuable perspectives on potential clinical settings.

Language: Английский

Recent advances in polydopamine-coated metal–organic frameworks for cancer therapy DOI Creative Commons

Jingchao He,

Guangtian Wang, Yongfang Zhou

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: April 1, 2025

The creation and development of classical multifunctional nanomaterials are crucial for the advancement nanotherapeutic treatments tumors. Currently, metal–organic frameworks (MOFs) modified with polydopamine (PDA) at forefront nanomedicine research, particularly in tumor diagnostics therapy, owing to their exceptional biocompatibility, expansive specific surface area, multifaceted functionalities, superior photothermal properties, which led significant advancements anti-tumor research. Consequently, a range anti-cancer strategies has been devised by leveraging capabilities MOFs, including intelligent drug delivery systems, photodynamic tailored microenvironment. In order gain deeper insight into role MOFs@PDA cancer diagnosis treatment, it is essential conduct comprehensive review existing research outcomes promptly analyze challenges associated biological applications. This will provide valuable perspectives on potential clinical settings.

Language: Английский

Citations

0