Graphitic Carbon Nitride: A Novel Two-Dimensional Metal-Free Carbon-Based Polymer Material for Electrochemical Detection of Biomarkers DOI Creative Commons
G. Kausalya Sasikumar, P. Raja, Peter Jerome

et al.

C – Journal of Carbon Research, Journal Year: 2024, Volume and Issue: 10(4), P. 98 - 98

Published: Nov. 27, 2024

Graphitic carbon nitride (g-C3N4) has gained significant attention due to its unique physicochemical properties as a metal-free, two-dimensional, carbon-based polymeric fluorescent substance composed of tris-triazine-based patterns with slight hydrogen content and carbon-to-nitrogen ratio 3:4. It forms layered structures like graphite demonstrates exciting unusual properties, making g-C3N4 widely used in nanoelectronic devices, spin electronics, energy storage, thermal conductivity materials, many others. The biomedical industry greatly benefited from excellent optical, electrical, characteristics, such abundance on Earth, affordability, vast surface area, fast synthesis. Notably, the heptazine phase displays stable electronic bands. Another quality this semiconductor material is fluorescence property, which also helpful preparing biosensors. Based g-C3N4, electrochemical biosensors have provided better biocompatibility, higher sensitivity, low detection limits, nontoxicity, selectivity, versatility functionalization for delicate identification target analytes. This review covers latest studies using efflorescent graphitic fabricate various biomarkers. Carbon nitrides been reported possess electroactivity massive surface-to-volume ratio, hydrogen-bonding functionality, thus allowing electrochemical-based, highly sensitive, selective platforms an entire array Considering preceding information, addresses fundamentals background numerous synthesis pathways. Furthermore, importance sensing diverse biomarkers emphasized article. discusses current status challenges future perspectives nitride-based sensors, open paths toward their practical application aspects clinical diagnostics.

Language: Английский

Supradecoration induced homogenous electrochemical sensing: development of Ru(ii) half sandwich complex as isoniazid and rifampicin dual sensor DOI Creative Commons

Mohd Mustafa,

Tabee Jan,

Mehdi Rohullah

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(9), P. 7004 - 7017

Published: Jan. 1, 2025

Homogenous electrochemical sensing using unmodified electrodes remove electrode fabrication challenges and prove effective for detecting sensitive bio-analytes without chances of surface degradation. This work envisages design optimization a ruthenium(ii) half-sandwich complex as supradecorated homogeneous sensor simultaneous detection rifampicin (RIF) isoniazid (INH) first-line anti-tuberculosis drugs in aqueous environments. The profile GCE/ruthenium(ii) was analyzed cyclic voltammetry, differential pulse voltammetry impedance spectroscopy (EIS). results indicate significant parameters corroborating enhanced propensity over bare GCE estimation RIF INH binary mixture. INZ analytical figure merit has been corroborated with their relative supra interactional propensity. Supra also predicted to be the plausible mechanism sensing. Under optimized conditions depicted limits 1.2 μM, limit 32 nM. comparative study analytes individually high sensitivity 24.57 μA μM-1 cm-2 1.69 under linear response range 0.29-3.72 μM 4.9-82.22 respectively. homogenous compared other modified analytes. A antibiotic contaminant recovery pharmaceutical formulations, municipal water supplies Dal lake spiked well unspiked observed portraying real time application expresses excellent stability reproducibility. presence potential redox active biological interfering agents confirmed selectivity towards

Language: Английский

Citations

0
Graphitic Carbon Nitride: A Novel Two-Dimensional Metal-Free Carbon-Based Polymer Material for Electrochemical Detection of Biomarkers DOI Creative Commons
G. Kausalya Sasikumar, P. Raja, Peter Jerome

et al.

C – Journal of Carbon Research, Journal Year: 2024, Volume and Issue: 10(4), P. 98 - 98

Published: Nov. 27, 2024

Graphitic carbon nitride (g-C3N4) has gained significant attention due to its unique physicochemical properties as a metal-free, two-dimensional, carbon-based polymeric fluorescent substance composed of tris-triazine-based patterns with slight hydrogen content and carbon-to-nitrogen ratio 3:4. It forms layered structures like graphite demonstrates exciting unusual properties, making g-C3N4 widely used in nanoelectronic devices, spin electronics, energy storage, thermal conductivity materials, many others. The biomedical industry greatly benefited from excellent optical, electrical, characteristics, such abundance on Earth, affordability, vast surface area, fast synthesis. Notably, the heptazine phase displays stable electronic bands. Another quality this semiconductor material is fluorescence property, which also helpful preparing biosensors. Based g-C3N4, electrochemical biosensors have provided better biocompatibility, higher sensitivity, low detection limits, nontoxicity, selectivity, versatility functionalization for delicate identification target analytes. This review covers latest studies using efflorescent graphitic fabricate various biomarkers. Carbon nitrides been reported possess electroactivity massive surface-to-volume ratio, hydrogen-bonding functionality, thus allowing electrochemical-based, highly sensitive, selective platforms an entire array Considering preceding information, addresses fundamentals background numerous synthesis pathways. Furthermore, importance sensing diverse biomarkers emphasized article. discusses current status challenges future perspectives nitride-based sensors, open paths toward their practical application aspects clinical diagnostics.

Language: Английский

Citations

0