Enhancing the Stability and Anticancer Activity of Escherichia coli Asparaginase Through Nanoparticle Immobilization: A Biotechnological Perspective on Nano Chitosan DOI Open Access
Fahad Alharthi,

Hussam A. Althagafi,

Ibrahim Jafri

et al.

Polymers, Journal Year: 2024, Volume and Issue: 16(23), P. 3260 - 3260

Published: Nov. 23, 2024

There is a shortage in the experimental research directly comparing effectiveness of different nanoparticles boosting asparaginase (ASNase) activity. This study assessed impact various on enhancing ASNase activity, stability, and anticancer effects through immobilization.

Language: Английский

Nanozyme-Based Cancer Nanotheranostics: Emerging Applications and Challenges in Brain Cancer Therapeutics DOI Creative Commons
Alexandra A.P. Mansur, Herman S. Mansur

Journal of Nanotheranostics, Journal Year: 2025, Volume and Issue: 6(1), P. 4 - 4

Published: Jan. 31, 2025

Regrettably, despite undeniable advances in cancer diagnosis and therapy, primary brain (or cancer) remains one of the deadliest forms malignant tumors, where glioblastoma (GBM) is known as most diffuse glioma astrocytic lineage. Fortunately, to improve this scenario, remarkable progress nanotechnology has brought new promise raised expectations treatment. Nanomedicine, principally an area amalgamating with biology medicine, demonstrated a pivotal role, starting earliest detection while also offering novel multimodal therapy alternatives. In vast realm nanotechnology, nanozymes, type nanomaterial intrinsic enzyme-like activities characteristics connecting fields nanocatalysts, enzymology, biology, have emerged powerful nanotools for theranostics. Hence, fascinating field research experienced exponential growth recent years. As it virtually impossible cover all literature on broad domain science paper, review focuses presenting multidisciplinary approach, its content extending from fundamental knowledge nanozymes enzyme-mimicking catalysis targeting cancers. Although we are at very early stages research, can be envisioned that strategic development theranostics will positively offer disruptive nanoplatforms future nano-oncology.

Language: Английский

Citations

2
A dual-mode sensing system for xanthine oxidase detection based on nitrogen-doped carbon dots and iron-cobalt oxide nanosheets DOI

Junshu Wang,

Jinying Liu, Chenyu Zhou

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 415, P. 135954 - 135954

Published: May 11, 2024

Language: Английский

Citations

5
Smartphone-Enhanced Nanozyme Sensors: Colorimetric and Fluorescence Sensing Techniques DOI Creative Commons

Tileshwar Sahare,

Nandini Singh,

Badri Narayana Sahoo

et al.

Biosensors and Bioelectronics X, Journal Year: 2024, Volume and Issue: unknown, P. 100544 - 100544

Published: Sept. 1, 2024

Language: Английский

Citations

5
Carbon-based nanozymes for cancer therapy and diagnosis: A review DOI Creative Commons
Marco Cordani, Jesús Fernández‐Lucas, Arezoo Khosravi

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139704 - 139704

Published: Jan. 1, 2025

Language: Английский

Citations

0
Biological activation of Fenton reaction in polymeric nanoreactors driven by ferrocene-containing membranes: a microenvironment dependent study DOI Creative Commons

Alejandro González Vivancos,

Yang Zhou, Uwe Lappan

et al.

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Nanocatalytic medicine for treating cancer requires effective, versatile and novel tools approaches to significantly improve the therapeutic efficiency interactions of (non-)enzymatic reactions. However, it is necessary develop nanotechnologies capable selectively killing tumour cells without harming normal cells. Their characteristics should be adaption tumours' extra- intracellular environment being specifically active. To contribute this common goal, we propose use pH- redox-responsive ferrocene containing polymersomes (FcPsomes). This allows regulation their biological activities controlled production radicals

Language: Английский

Citations

0
Optimizing cancer therapy through metal organic frameworks-based nanozymes DOI

Qinxin Zhang,

Sai Chen,

Hongwei Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141409 - 141409

Published: Feb. 1, 2025

Language: Английский

Citations

0
Phyto-assisted eco-benevolent synthesis of oxidase-mimic Cu–Mn3O4 as an antibacterial and antiproliferative agent DOI

Ankita Shome,

Salim Ali,

Debadrita Roy

et al.

Bioprocess and Biosystems Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 3, 2025

Language: Английский

Citations

0
The exploration of Nanozymes for biosensing of pathological states tailored to clinical theranostics DOI

Abdul Sayeed Khan,

Sudhir Kumar Sahu, Santosh Kumar Dash

et al.

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: unknown

Published: July 23, 2024

The nanozymes (NZs) are the artificial catalyst deployed for biosensing with their uniqueness (high robustness, surface tenability, inexpensive, and stability) obtaining a better response/miniaturization of varied sensors than traditional ancestors. Nowadays, nanomaterials broadened scale such as metal-organic frameworks (MOFs), metals/metal oxides widely engaged in generating NZ-based biosensors (BS). Diverse strategies like fluorescent, colorimetric, surface-enhanced Raman scattering (SERS), electrochemical sensing principles were implemented signal transduction NZs. Despite broad advantages, numerous encounters (like specificity, feasibility, stability, issues scale-up) affecting potentialities NZs-based BS, thus need prior attention promising exploration revolutionary outcome advanced theranostics. This review includes different types NZs, progress NZs tailored bio-sensing techniques detecting abundant bio analytes theranostic purposes. Further, discussion highlighted some recent challenges along progressive way possibly overcoming followed by commercial outbreaks.

Language: Английский

Citations

2
Frontiers of nanozymes: Enhancing cancer diagnosis and therapeutic strategies DOI

Mohd Shoab Ali,

Saurav Kumar Jha, Garima Gupta

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112043 - 112043

Published: Oct. 1, 2024

Language: Английский

Citations

1
Chiral nanoenzymes: synthesis and applications DOI
Xiaohui Niu, Jianying Zhang,

Mei Yuan

et al.

Microchimica Acta, Journal Year: 2024, Volume and Issue: 191(12)

Published: Nov. 4, 2024

Language: Английский

Citations

1